Objective This study was conducted to evaluate the effects of fish oil omega-3 fatty acid supplementation on mental health parameters and metabolic status of women with polycystic ovary syndrome (PCOS).Methods This randomized double-blind, placebo-controlled trial was conducted on 60 women with PCOS, aged 18–40 years old. Participants were randomly assigned into two groups to receive either 2 × 1000 mg/day fish oil omega-3 fatty acid (n = 30) or placebo (n = 30) after lunch for 12 weeks. Metabolic profiles were quantified at baseline and after the 12-week intervention.Results Compared with the placebo, omega-3 fatty acid intake led to a significant improvement in Beck Depression Inventory [β (difference in the mean outcomes measures between treatment groups after intervention) –1.05; 95% CI: –1.84, –0.26; p = .01], general health questionnaire (β –1.68; 95% CI: –3.12, –0.24; p = .02) and depression anxiety and stress scale (β –2.03; 95% CI: –3.60, –0.46; p = .01). Omega-3 fatty acid supplementation significantly decreased serum insulin levels (β –2.09 µIU/mL; 95% CI: –3.77, –0.41; p = .01), homeostasis model of assessment-insulin resistance (β –0.74; 95% CI: –1.13, –0.34; p < .001), total testosterone (β –0.23 ng/mL; 95% CI: –0.39, –0.06; p = .03) and hirsutism (β –0.75; 95% CI: –1.17, –0.33; p = .001), and significantly increased the quantitative insulin sensitivity check index (β 0.01; 95% CI: 0.003, 0.02; p = .008) compared with the placebo. Additionally, omega-3 fatty acid intake resulted in a significant decrease in high sensitivity C-reactive protein (β –1.46 mg/L; 95% CI: –2.16, –0.75; p < .001) and malondialdehyde (β –0.28 µmol/L; 95% CI: –0.52, –0.05; p = .03); also significant rises in plasma total glutathione (β 59.09 µmol/L; 95% CI: 7.07, 111.11; p = .02) was observed compared with the placebo. Omega-3 fatty acid supplementation did not change other metabolic parameters.Conclusion Overall, omega-3 fatty acid supplementation for 12 weeks to patients with PCOS had beneficial effects on mental health parameters, insulin metabolism, total testosterone, hirsutism and few inflammatory markers and oxidative stress.
Editing a long period program for makingefficient the supply part has a positive effect on the country ,s economy and developing Iran,s function in the world energy market.one of the greatest consequenses in making efficient the supply part is yield,s improvement and the reduction of producing environmental pollatants orginated from producing energy .
Several approaches in energy distribution section are presented: spontaneous production of electricity and heat .cooling the entered air into the gas turbine .usage the expansion turbine and choosing the appropriate mixture in distribution of energy carriers are some of approaches.
In the present study long-term program of using the simultaneous production units of heat and electricity that is prepared according to the minimization of the total economic prices of energy –supllying system.investment component operating cost and fuel prices has been considered.
In termoeconomic part, photovoltaic system because of having better efficiency was put under consideration.It show that the suspense ofbuilding itwith the power 703 wh will cost 18620000 Rials a month that It’s durability is between 10 to 12years .also we compared this suspens with the consumptional electric price during 12 years.
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