Meropi Kontogianni

Harokopio University of Athens

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Michael Georgoulis

Harokopio University of Athens

Nikos Yiannakouris

Harokopio University of Athens

Ioanna Kechribari

Harokopio University of Athens

Demosthenes B. Panagiotakos

Harokopio University of Athens

Mary Yannakoulia

Harokopio University of Athens

George Papatheodoridis

National and Kapodistrian University of Athens

ΑA

Αlexandra Alexopoulou

Hippocration General Hospital

Kallirroi Lamprou

Evangelismos Hospital

Ioannis Gioulbasanis

University of Rijeka

Evangelia Fappa

University of Peloponnese

Cooperative Institutions

National and Kapodistrian University of Athens

183

Harokopio University of Athens

156

Charité - Universitätsmedizin Berlin

Laiko General Hospital of Athens

Inserm

Instituto de Salud Carlos III

Istituti di Ricovero e Cura a Carattere Scientifico

Ghent University

University of Milan

University College London

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Blood Leptin and Adiponectin as Possible Mediators of the Relation Between Fat Mass and BMD in Perimenopausal Women

Journal of Bone and Mineral Research (2004)

Meropi Kontogianni Urania Dafni John G. Routsias Fotini N. Skopouli

Fat mass is a predictor of BMD; however, the mechanisms involved remain uncertain. Two adipokines, leptin and adiponectin, were examined as potential mediators of this relation in 80 perimenopausal women. Adiponectin did not exert any effect on BMD, whereas leptin exerted a negative one, with insulin acting as a confounder to this relation.Fat mass is an important determinant of bone density, but the mechanism involved in this relation is uncertain. Leptin and adiponectin, as circulating peptides of adipocyte origin, are potential contributors to this relation. We investigated the role of leptin and adiponectin in mediating fat mass effects on the skeleton of perimenopausal women.Twenty-five premenopausal and 55 postmenopausal, healthy women (42-68 years old) participated in our study. Lumbar spine BMD (BMD(L2-L4)) and total body BMC (TBBMC) were measured with DXA, leptin levels with ELISA, and adiponectin levels with radioimmunoassay (RIA). Additionally, body composition analysis was performed, as well as measurements of several hormones.It was shown that serum leptin levels were negatively correlated with BMD (beta = -0.005, p = 0.027) and TBBMC (beta = -14.32, p = 0.013). The above correlation was observed only when serum insulin levels were included, as an independent variable, in the regression analysis model. Adiponectin was not significantly correlated with BMD(L2-L4) nor with TBBMC, either in the presence or absence of insulin.Circulating adiponectin does not seem to exert any effect on bone mass. In contrast, circulating leptin showed a negative correlation with bone mass, dependent on serum insulin levels.

10.1359/jbmr.040107

Cite

Citations (204)

Improvements in Plasma Tumor Necrosis Factor-Alpha Levels after a Weight-Loss Lifestyle Intervention in Patients with Obstructive Sleep Apnea

Life (2022)

Michael Georgoulis Nikos Yiannakouris Ρωξάνη Τέντα Ioanna Kechribari Kallirroi Lamprou

Obstructive sleep apnea (OSA) and systemic inflammation typically coexist within a vicious cycle. This study aimed at exploring the effectiveness of a weight-loss lifestyle intervention in reducing plasma tumor necrosis factor-alpha (TNF-a), a well-established modulator of systematic inflammation in OSA. Eighty-four adult, overweight patients with a diagnosis of moderate-to-severe OSA were randomized to a standard care (SCG, n = 42) or a Mediterranean lifestyle group (MLG, n = 42). Both groups were prescribed continuous positive airway pressure (CPAP), while the MLG additionally participated in a 6-month behavioral intervention aiming at healthier weight and lifestyle habits according to the Mediterranean pattern. Plasma TNF-a was measured by an immunoenzymatic method both pre- and post-intervention. Drop-out rates were 33% (n = 14) for the SCG and 24% (n = 10) for the MLG. Intention-to-treat analysis (n = 84) revealed a significant decrease in median TNF-a only in the MLG (from 2.92 to 2.00 pg/mL, p = 0.001). Compared to the SCG, the MLG exhibited lower follow-up TNF-a levels (mean difference adjusted for age, sex, baseline TNF-a and CPAP use: -0.97 pg/mL, p = 0.014), and further controlling for weight loss did not attenuate this difference (p = 0.020). Per protocol analyses (n = 60) revealed similar results. In conclusion, a healthy lifestyle intervention can lower plasma TNF-a levels in patients with OSA.

10.3390/life12081252

Cite

Citations (2)

Αξιολόγηση εργαστηριακών δεικτών

Meropi Kontogianni Μαρία Γιαννακούλια Kalliopi Zafeirenia Karatzi Evangelia Fappa Μερόπη Κοντογιάννη

ΚΛΙΝΙΚΗ ΔΙΑΤΡΟΦΗ Ι [ΧΑΡΟΚΟΠEΙΟ ΠΑΝEΠΙΣΤΗΜΙΟ, ΣΧΟΛΗ EΠΙΣΤΗΜΩΝ ΥΓEΙΑΣ ΚΑΙ ΑΓΩΓΗΣ, ΤΜΗΜΑ EΠΙΣΤΗΜΗΣ ΔΙΑΙΤΟΛΟΓΙΑΣ - ΔΙΑΤΡΟΦΗΣ]

Source

Cite

Citations (0)

OC53 - Dietary patterns and risk of childhood overweight/obesity or metabolically unhealthy childhood obesity: A systematic review and meta-analysis

Meropi Kontogianni Athanasia Kyrkili

10.26226/m.6671b5796ad8b7afd6ba70bd

Cite

Citations (0)

PP139-MON PREVALENCE OF NUTRITIONAL RISK AND NUTRITIONAL SCREENING IN GREEK HOSPITALS: PRELIMINARY RESULTS

Clinical Nutrition Supplements (2012)

Michail Chourdakis E. Mavridou Ioannis Doundoulakis Meropi Kontogianni Dimitrios Kouvelas

10.1016/s1744-1161(12)70478-7

Cite

Citations (0)

FRI-076 Physical frailty diagnosed by short physical performance battery test is an independent poor prognostic factor of 360-day mortality in patients with liver cirrhosis

Journal of Hepatology (2024)

Eleni Geladari Theodoros Alexopoulos Larisa Vasilieva Meropi Kontogianni Roxani Tenta

10.1016/s0168-8278(24)00861-4

Cite

Citations (0)

An international study of clinical, demographic and competence-related determinants of communication with professionals

Research Square (Research Square) (2024)

Juan Ignacio Arrarás Johannes M. Giesinger Omar Shamieh Iqbal Bahar Michael Koller

Abstract Purpose: This study aims to identify the clinical and demographic determinants of patients’ communication with professionals in an international sample of cancer patients. Methods: Cancer patients completed EORTC communication questionnaire QLQ-COMU26 to assess ten areas of communication with their doctor or nurses plus another item to assess how competent they felt when communicating with professionals. Bivariable analyses and multivariable linear regression models were performed separately for each QLQ-COMU26 area. Results: 988 patients from 15 centres in 13 countries (five cultural areas) were included in the study. Higher age was related to higher level of communication in eight QLQ-COMU26 areas. Males reported higher level of communication in three areas. Lower levels of studies and a higher level of perceived competence when communicating with professionals were related to higher level of communication in the ten QLQ-COMU26 areas. Communication was of a higher level with nurses than with doctors in four areas. Having received previous treatment with the same doctor or group of nurses was related to higher communication levels in seven areas. Lack of comorbidity was related to higher communication levels in two areas. Various differences in determinants were found among tumour sites Conclusion Our regression model has shown several relationships between communication and the demographic and clinical variables that may help to identify patients at risk of poor communication. Future studies could focus on communication at diagnosis and in follow-up, and on areas such as assessing the particularities of communication between patient and professionals in relation to each cancer type.

10.21203/rs.3.rs-4456065/v1

Cite

Citations (0)

Sustained improvements in the cardiometabolic profile of patients with obstructive sleep apnea after a weight-loss Mediterranean diet/lifestyle intervention: 12-month follow-up (6 months post-intervention) of the “MIMOSA” randomized clinical trial

Nutrition Metabolism and Cardiovascular Diseases (2023)

Michael Georgoulis Nikos Yiannakouris Ioanna Kechribari Kallirroi Lamprou Eleni Perraki

Mediterranean Diet

10.1016/j.numecd.2023.02.010

Cite

Citations (10)

M.611 Epidemiology of overweight and obesity in a Greek adult population; The Attica study

Atherosclerosis Supplements (2004)