Quantitative relations between campylobacteria and sanitary indicating bacteria in surface waters were studied. A correlation between numbers of campylobacteria and lactose-positive bacteria was revealed.
Sensitivity of 179 strains of thermophilic Campylobacter to 21 chemotherapeutic drugs was studied. Activity of the antibacterial agents against the pathogens was estimated by the MICs. The MIC50 and MIC90 were also determined. All the Campylobacter strains were sensitive to gentamicin, chloramphenicol, neomycin, furazolidone and furagin and resistant to cefazolin, polymyxin E, rifampicin, vancomycin and bacitracin. Differences in the attitude of the Campylobacter isolates from various sources and patients of various age groups to the chemotherapeutic drugs were detected. Possible consideration of the results of comparison of R spectra of Campylobacter strains and the levels of their resistance to antimicrobial drugs as epidemiological markers is discussed.
Altogether 31 children with chronic gastritis were examined. Three diagnostic tests were employed for detecting Campylobacter pylori. The clinical signs of the disease and the endoscopic features of the gastric mucosa are described.
Step-by-step therapy of patients with pneumonia and exacerbated chronic bronchitis with amoxyclav (amoxycillin/potassium clavulanate) in a dose of 1.2 g administered intravenously dropwise every 8 hours for the first 2 days of the treatment with subsequent oral use of the drug in a dose of 625 mg thrice a day for 5 days proved to be highly efficient. The recovery and improvement were stated in 19 (95 per cent) out of 20 patients. The adverse reaction (urticaria) was observed in 1 patient. Identical results were recorded in a comparative randomized trial with the use of cefotaxime in a dose of 1.0 g intramuscularly every 8 hours for 7 days. The pharmacoeconomic estimate showed the expediency of the step-by-step therapy with the use of amoxycillin/potassium clavulanate.
Morbidity rises during the period of summer and autumn are characteristic of bacterial dysentery in Algeria. During the last 18 years no essential changes in the seasonal character of bacterial dysentery were observed in the country taken as a whole. However, in different climatic and geographical zones of the country the seasonal character of dysentery greatly varies from one zone to another and essentially differs from the seasonal character of dysentery morbidity, typical of the country as a whole for many years. The most pronounced manifestations of seasonal rises are observed in the Sahara zone. The seasonal character of dysentery is formed mainly by morbidity among patients belonging to 3 age groups. The seasonal rises of dysentery can be probably explained by the complex of social and climatic factors, as well as by the biological features of the causative agents of this disease.
The clinical course and epidemiological features of campylobacteriosis in Moscow and Moscow Province in 1986-1987 are described. The specific proportion of this infection in the structure of acute enteric infections is, on the average, 4.8%. The level of Campylobacter contamination of animals and birds and their role in the spread of campylobacteriosis have been established. The possible ways and factors of the transfer of this infection are discussed.
The results of the analysis of the epidemic situation in Campylobacter infection and the epidemiological markers of the strains of the infective agent have demonstrated that Campylobacter infection, registered as single cases among the residents of Vologda, has an epidemic character. An intensive and uncontrolled process among fowl (chickens) and the absence of effective measures of specific prophylaxis make it necessary that a system of hygienic measures be given priority in the complex of measures aimed at the prophylaxis of Campylobacter infection.
Examinations of the gastric mucosa biopsy specimens from 38 children suffering from chronic gastritis have revealed Campylobacter bacteria in 21 (55.3%). Studies of the cultural, morphologic, and biochemical characteristics of the isolated strains have identified them as C. pylori.
Analysis of morbidity of dysentery and the rest diarrheal affections according to the books for primary recording of patients at one of the large administrative territories of the Northern Africa showed that official statistics reflected only 1/13 of dysentery patients who applied for medical aid (18.2 and 236.3 per 100 000 residents, respectively). Morbidity index of the rest of diarrheal affections constituted 2424.5 per 100 000. The mean lethality in diarrhea affections (including dysentery) was 1.7%. The fact that in the examination of 439 persons who came in contact with the patients suffering from typhoid fever the causative agents of dysentery were isolated in 19 (4.3%) indicated their wide circulation among the population.
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