Objective To explore the effects of mild hypothermia on tumor necrosis factor alpha(TNF-α),interleukin-6(IL-6) and intedeukin-10(IL-10)in serum of patients with severe traumatic brain injury and its clinical significance.Methods Mild hypothermia was used within 24 hours after injury to keep the rectal temperature at 33℃-35℃ for five days in 28 patients who suffered from severe brain injury with GCS score of 3-8(mild hypothermia group).And 20 patients who suffered from Severe brain injury with GCS score of 3-8 were taken as control group.The dynamic changes of Serum TNF-α,IL-6 and IL-10 at days 1,3 and 5 respectively after trauma were monitored using ELISA.Results Levels of serum TNF-α and IL-6 decreased more significantly in the mild hypothermia group than those in the control group(P0.05),but levels of serum IL-10 increased in mild hypothermia group(P0.05).Conclusion Mild hypothermia can regulate serum cytokines levels in patients with severe brain injury and hence reduce incidence of multiple organ dysfunction syndrome.
Objective To investigate the serum detection of the serum glutamate dehydrogenated shuttle antibody(GAD-Ab), islet cell antibody(ICA) and insulin auto antibodies(IAA) and its clinical significance in patients with diabetes. Methods The serum GAD-Ab, ICA, IAA of 41 cases of type 1 diabetes、45 patients with type 2 diabetes mellitus(NIDDM) patients and 46 healthy human were determined by ELISA method. Results The positive rate of type 1 diabetes mellitus group GAD-Ab, ICA, IAA were 75.6%, 36.6%, 24.4%; the positive rate of type 2 diabetes mellitus group of 3 kinds of antibodies were 8.9%, 11.1%, 11.1%; the control group of healthy human GAD-Ab, ICA, IAA were negative. Results in patients with type 1 diabetes, serum GAD-Ab, ICA, IAA positive rate was higher than that of type 2 diabetic patients and healthy controls. Conclusion The serum GAD-Ab, ICA, IAA detection had important clinical significance in early diagnosis and prediction of type 1 diabetes mellitus;It was an important serological index in differential diagnosis of type 1 diabetes and type 2 diabetes mellitus; and GAD-Ab, ICA, IAA joint detection could improve the positive rate, to avoid missed diagnosis.
A new image edge detection algorithm which is based on the theory of fuzzy gradient is proposed in the paper.The steps of the algorithm is as follows:firstly,the original gray image is changed into fuzzy matrix by the normalized tangent function;secondly,gradient matrix of the fuzzy matrix mentioned above is computed;thirdly,the fuzzy gradient matrix which is also called fuzzy set of the gradient matrix is obtained using sine function;and in the end,appropriate threshold which is identified by genetic algorithm based on normalized real-coded is used to segment the fuzzy gradient set into two subsets:the edge point set and non-edge point set.At this point,the image edge points are obtained.To test the speed and accuracy of the algorithm for detecting edge of micro-part image,the experiments have been done taking different kinds of micro-gear as the subjects.The experimental results show that the detecting accuracy is better than 10 μs and the processing time is generally about 1 s.Compared with Canny or Pal-King algorithms,it could be concluded that the performance of proposed new algorithm is the best.
Objective: To avaluate the trends and the clinical changes in tuberculosis of pharynx and larynx, Methods: The clinical data of 39 patients with pathologically confirmed tuberculosis of pharynx and larynx were retrospectively analyzed. Results: Thirty-nine patients had many different features as compared with those of the past in such aspects as age, local lesion, and clinical manifestations. All patients were cure by anti-tuberculosis medicine. Conclusion: Tuberculosis of pharynx and larynx is unrecognized for the diversity feature. Early biopsy examination would avoide misdiagnosis.
This paper contributes to the recently renewed debate over the relation between sciences and humanities. My major focus is to assess four debates about science, namely, J. Rousseau's critique about science, W. Windelband and H. Rickert's distinction between natural science and cultural science, C. P. Snow's study about two cultures, and the science war. On the basis, this paper points out that in order to resolve the problem of the relation between sciences and humanities, we must introduce existential and contextual concept.
Objective To study the effect of clinical nursing path( CNP) in health education on patients with Gallbladder polyps undergoing endoscopic retrograde cholangio——pancreatography( ERCP). Methods From January 2009 to December 2013,230 patients with ERCP were divided randomly into control and experimental groups,with 115 cases in each group. The patients in the control group were givenhealth education in the traditional way,while the patients in the experiment group were given health education via CNP. Comparisons were conducted on the perception of the situation and satisfaction of care during ERCP. Results The length of hospital stay in the experimental group was significantly less than that of the control group. The awareness of ERCP in the experimental group was significantly superior to that of the control group. Significant difference was also observed on nursing satisfaction between the two groups. Conclusion Health education via CNP for ERCP patients helps reduce patient anxiety and enhance the patient 's understanding of the depth of disease,improve patient and with the level and quality of health education nurse.
