Ronald L. Johnson

Arkansas State University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Ruili Huang

National Center for Advancing Translational Sciences

Wenwei Huang

National Center for Advancing Translational Sciences

Patrick Bird

bioMérieux (United States)

James Inglese

National Institutes of Health

John Mills

bioMérieux (United States)

Jennifer Wichterman

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Christopher P. Austin

Jersey Shore University Medical Center

Jong Yeon Hwang

Korea Research Institute of Chemical Technology

Peter N. Devreotes

Johns Hopkins University

Matthew P. Scott

Stanford University

Cooperative Institutions

bioMérieux (United States)

175

QED Labs

110

National Institutes of Health

Harvard University

Johns Hopkins University

National Center for Advancing Translational Sciences

Howard Hughes Medical Institute

Stanford University

University of North Carolina at Chapel Hill

National Human Genome Research Institute

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Table 1, Final 1536-well assay protocol

Wenwei Huang Ronald L. Johnson Ruili Huang Jennifer Wichterman Jong Yeon Hwang

Table (database)

Source

Cite

Citations (0)

High-throughput screening for genes that prevent excess DNA replication in human cells and for molecules that inhibit them

Methods (2012)

Chrissie Y. Lee Ronald L. Johnson Jennifer Wichterman-Kouznetsova Rajarshi Guha Marc Ferrer

DNA re-replication

Endoreduplication

10.1016/j.ymeth.2012.03.031

Cite

Citations (12)

Temporal Changes of Largemouth Bass Alleles in a Northern Arkansas Reservoir Stocked with Florida Bass

Journal of the Arkansas Academy of Science (2009)

Ryan M. Allen Ronald L. Johnson

Southwest Electric Power Company (SWEPCO) Lake in northwest Arkansas is a thermal cooling pond for the Flint Creek Power Station. This reservoir has been regularly stocked with Florida bass (Micropterus floridanus) on top of a pre-existent largemouth bass (M. salmoides) population since its creation in 1976. Allozyme analysis of diagnostic loci in 1995-1996 revealed that 62% of the alleles were Florida bass alleles and that most fish were FX hybrids (77%). Microsatellite analysis of diagnostic loci in 2006 revealed that 78% of the alleles were Florida bass alleles and that most fish were FX-Florida hybrid bass (59%), with the remainder designated as Florida bass. The ongoing stocking of Florida bass and the possibility of a selective advantage for Florida bass alleles in a thermal pond may account for these temporal reductions in largemouth bass allele frequencies.

Source

Cite

Citations (6)

Overexpression of the cAMP receptor 1 in growing Dictyostelium cells

Biochemistry (1991)

Ronald L. Johnson Roxanne A. Vaughan Michael J. Caterina Peter J.M. Van Haastert Peter N. Devreotes

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOverexpression of the cAMP receptor 1 in growing Dictyostelium cellsRonald L. Johnson, Roxanne A. Vaughan, Michael J. Caterina, Peter J. M. Van Haastert, and Peter N. DevreotesCite this: Biochemistry 1991, 30, 28, 6982–6986Publication Date (Print):July 16, 1991Publication History Published online1 May 2002Published inissue 16 July 1991https://pubs.acs.org/doi/10.1021/bi00242a025https://doi.org/10.1021/bi00242a025research-articleACS PublicationsRequest reuse permissionsArticle Views230Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

10.1021/bi00242a025

Cite

Citations (49)

Retribution and Retaliation

Ronald L. Johnson

Retributive justice

Source

Cite

Citations (0)

G-Protein-linked Signaling Pathways Mediate Development in Dictyostelium

Cold Spring Harbor Symposia on Quantitative Biology (1992)

Ronald L. Johnson Robert E. Gundersen Dale Hereld Geoffrey S. Pitt Stuart Tugendreich

Dictyostelium is a simple model organism for developmental studies. Under conditions of growth, single amoebae comprise a homogeneous population of cells, but when deprived of nutrients, cells aggregate to form a multicellular structure consisting of several different cell types (Fig. 1). Development is first detected when amoebae migrate to central points within a monolayer and form aggregates of many thousands of cells. Cells become tightly adherent within the aggregate to create a mound, upon which a single tip forms. This structure rises, falls over, and forms a migrating pseudoplasmodium or "slug" with the tip forming the anterior end. Slugs are about a millimeter in size and crawl about the surface. This migratory phase, which can be bypassed, is influenced by multiple factors, such as light, temperature, and pH. Culmination results in a sorocarp or fruiting body, which consists of a stalk of dead vacuolated cells...

Multicellular organism

Slug

10.1101/sqb.1992.057.01.022

Cite

Citations (15)

Table 4, Profiling results for ML209 in a panel of 21 nuclear receptors for antagonistic activity

Wenwei Huang Hang Wang Ronald L. Johnson Ruili Huang Erika Englund

Profiling (computer programming)

Table (database)

Source

Cite

Citations (0)

Evaluation of VIDAS® Immuno-Concentration Salmonella/VIDAS Salmonella Immunoassay Method for Detection of Salmonella in Selected Foods: Collaborative Study

Journal of AOAC International (2002)

Wendy A Lepper Ann Schultz Michael S Curiale Ronald L. Johnson J Agin

Abstract The VIDAS Immuno-concentration Salmonella (ICS)/VIDAS Salmonella (SLM) immunoassay method for the detection of Salmonella was compared to the Bacteriological Analytical Manual (BAM)/AOAC culture method in a collaborative study. Thirty-two laboratories participated in the evaluation. Each laboratory tested one or more of the 6 test products: milk chocolate, nonfat dry milk, dried whole egg, soy flour, ground black pepper, and ground raw turkey. The 2 methods were in agreement for 1266 of the 1440 samples. Of the 174 samples not in agreement, 69 were VIDAS ICS/SLM-positive and BAM/AOAC-negative and 105 were VIDAS ICS/SLM-negative and BAM/AOAC-positive.

10.1093/jaoac/85.3.609

Cite

Citations (4)

Optical Distribution Manifolds For Phased Array Antennas

Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE (1988)

Joel L. Guggenmos Ronald L. Johnson Bernard D. Seery

A conceptual space-fed architecture is presented that may offer potential advantages over conventional constrained-feed approaches. Fiber or free space optics may be used to control switching functions, distribute signals, achieve beam steering, or injection lock impact avalanche and transmit time (IMPATT) diodes. Fiber optics and monolithic optical technology may reduce weight, size, power, and cost if the high performance required for signal distribution to array elements is achieved.

Beam steering

Free-Space Optical Communication

SIGNAL (programming language)

Phased-array optics

10.1117/12.944197

Cite

Citations (1)

Identification of Aminothienopyridazine Inhibitors of Tau Assembly by Quantitative High-Throughput Screening

Biochemistry (2009)

Alex Crowe Wenwei Huang Carlo Ballatore Ronald L. Johnson Anne‐Marie L. Hogan

Inclusions comprised of fibrils of the microtubule- (MT-) associated protein tau are found in the brains of those with Alzheimer's disease (AD) and other neurodegenerative tauopathies. The pathology that is observed in these diseases is believed to result from the formation of toxic tau oligomers or fibrils and/or from the loss of normal tau function due to its sequestration into insoluble deposits. Hence, small molecules that prevent tau oligomerization and/or fibrillization might have therapeutic value. Indeed, examples of such compounds have been published, but nearly all have properties that render them unsuitable as drug candidates. For these reasons, we conducted quantitative high-throughput screening (qHTS) of approximately 292000 compounds to identify drug-like inhibitors of tau assembly. The fibrillization of a truncated tau fragment that contains four MT-binding domains was monitored in an assay that employed complementary thioflavin T fluorescence and fluorescence polarization methods. Previously described classes of inhibitors as well as new scaffolds were identified, including novel aminothienopyridazines (ATPZs). A number of ATPZ analogues were synthesized, and structure-activity relationships were defined. Further characterization of representative ATPZ compounds showed they do not interfere with tau-mediated MT assembly, and they are significantly more effective at preventing the fibrillization of tau than the Abeta(1-42) peptide which forms AD senile plaques. Thus, the ATPZ molecules described here represent a novel class of tau assembly inhibitors that merit further development for testing in animal models of AD-like tau pathology.

Tau protein

Tau Pathology

10.1021/bi9006435

Cite

Citations (101)