Solution-processed semiconductors have opened promising avenues for next-generation semiconductor and optoelectronic industries. Colloidal quantum dots (QDs) as one of the most typical materials are widely utilized for the design and development of light-emitting diodes, photodetectors, and solar cells. Recently, an emerging process of PbS QD ink has been employed to attain world record power conversion efficiency by surface passivation using a PbI2 ligand to form PbI2–PbS and the process optimization in the field of photovoltaics. However, the bonding and debonding of the ligands on the surface of PbS QDs are dynamic reversible processes in an ink environment. The uncoordinated Pb2+ defects induced by unbonded PbS QDs serve as the recombination sites. Thus, the present ink process leaves much room for the enhancement by surface passivation of PbS QDs. Herein, we devise an efficient strategy with a supplementary phenethylammonium iodide (PEAI) ligand for the formation of the PEAI–PbS interface in PbS QD ink-processed solar cells. This newly developed method can not only improve the passivation on the QD surface by iodine ions but also simultaneously enhance the carrier collection efficiency by a graded energy alignment between PbI2–PbS and PEAI–PbS layers. The corresponding power conversion efficiency of the optimized device has significantly increased by approximately 20% more than the control device. As a result, such a robust and efficient method regarded as a strategic candidate can overcome the bottleneck of imperfect passivation caused by a large specific surface area and loose bonding ligands, eventually promoting the industrial application of QDs.
In this Letter, we investigate the terahertz (THz) electro-optic Kerr effect (KE) dynamics in LaAlO3 (LAO), a widely used substrate for thin-film preparation. We show that the KE dynamics strongly depend on the material anisotropy due to interference between THz field-induced and strain-induced optical birefringence. Such interference leads to quasi-phase matching conditions of the KE, which becomes strongly frequency dependent. Depending on the THz frequency, the KE exhibits a uni- and bipolar shape of the quadratic response. The demonstrated effects will be present in a wide variety of materials used as substrates in different THz pump laser-probe experiments and need to be considered in order to disentangle the different contributions to the measured ultrafast dynamic signals.
Drug-targeting strategies can increase the efficacy and reduce the side effects and toxicity of conventional chemotherapy or may lead to new radiolabeled molecules useful for diagnosis and therapy. To identify and characterize new carrier molecules, we evaluated a peptide that had been identified by phage display technology.The peptide p160 (VPWMEPAYQRFL) was prepared by solid-phase peptide synthesis and radiolabeled with (125)I or (131)I. The radiolabeled peptide and derivatives of it were used to study binding and internalization in vitro and to assess their distribution in tumor-bearing mice.Cell-binding assays on the human neuroblastoma cell line WAC 2 indicated the affinity and specificity of (125)I-labeled p160 toward neuroblastoma cells. Binding of the (125)I-labeled p160 was inhibited up to 95% by the unlabeled peptide. Furthermore, 50% of the total bound activity was internalized into the neuroblastoma cells. Biodistribution studies on nude mice showed a higher tracer accumulation in tumors than in most organs. Perfusion of the animals reduced uptake in all tissues, whereas tumor uptake remained constant. Fluorescence-activated cell-sorting studies with fluorescein isothiocyanate-labeled p160 demonstrated an increased fluorescence signal. Investigation of the binding properties of the fragments p160-8-1, p160-8-2, and p160-8-3 indicated that the sequence EPAYQR might be of significance for the binding of p160.These data indicate that the p160 peptide is an attractive candidate for the development of a neuroblastoma-specific vector that can be used for drug targeting or radiopeptide-based diagnosis and therapy.
The frontier knowledge of mechanical engineering and petroleum equipment is constantly updated, which puts forward the requirements for increasing the teaching knowledge points of mechanical specialty in petroleum colleges and universities.The certification of engineering education requires the control of theoretical class hours on the premise of student-centered.In order to explore the teaching strategies of mechanical specialty in petroleum industry colleges and universities under this new situation, the new knowledge in the field of mechanical engineering from design, manufacturing to application, and the frontier development trend in the field of petroleum machinery and equipment are combed.Combined with the requirements of the current machinery industry for personnel training, the case teaching method of integrating new knowledge of mechanical engineering into the professional course of petroleum machinery is proposed, and the teaching content is designed.The teaching method of this paper has been practiced and achieved a good effect.It is recognized that the application of case-based teaching method and the integration of new mechanical engineering knowledge into the specialized courses of petroleum machinery specialty can effectively solve the contradiction between the increase of knowledge points and the control of class hours under the new situation, and can train students' ability to comprehensively apply multi-disciplinary knowledge to solve complex engineering problems according to the requirements of professional certification, which is conducive to the cultivation of mechanical engineering talents meet the requirements of industrial development.
To study the distribution law of circumferential residual stress after casing expansion, using the finite element explicit dynamic analysis method analyzed the expansion process of expandable casings under different expansion rates. The analysis obtained key technical parameters of circumferential residual stress, average circumferential residual stress and elastic recovery along the wall thickness direction after casing expansion. It is recognized that the maximum residual tensile stress after casing expansion locates in the middle part of the casing thickness direction. The maximum residual compressive stress locates in the outer wall of the casing. When the expansion rate exceeds 18%, the increase in expansion rate will not lead to an increase in circumferential residual stress after casing expansion. The elastic recovery after casing expansion will reduce the circumferential stress during the expansion process. Considering collapse strength and the influence of elastic recovery on casing patch sealing performance after casing expansion, 23% is the most suitable expansion rate, which can effectively reduce the circumferential residual stress and improve the casing collapse strength. The analysis in this paper can provide bases for the calculation of casing collapse strength after expansion.
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