Enrique García‐España

Parc Científic de la Universitat de València

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Antonio Bianchi

University of Florence

119

Salvador Blasco

Universitat de València

109

Javier Pitarch‐Jarque

Parc Científic de la Universitat de València

M. Paz Clares

Universitat de València

Santiago V. Luis

Universitat Jaume I

Begoña Verdejo

Universitat de València

Conxa Soriano

Universitat de València

Andrea Bencini

University of Florence

José M. Llinares

Universitat de València

Estefanı́a Delgado-Pinar

Universitat de València

Cooperative Institutions

Universitat de València

206

Centre National de la Recherche Scientifique

Parc Científic de la Universitat de València

Consejo Superior de Investigaciones Científicas

University of Florence

Rede de Química e Tecnologia

Universitat Politècnica de València

Universitat Jaume I

Universidad de Granada

Universidade Nova de Lisboa

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Steady-state fluorescence emission studies on polyazacyclophane macrocyclic receptors and on their adducts with hexacyanocobaltate(III)

Journal of the Chemical Society. Dalton transactions (1995)

Alexandra Bernardo A. Jorge Parola Fernando Piña Enrique García‐España Victor Marcelino

The steady-state fluorescence emission spectra of the azacyclophanes 2,5,8,11-tetraaza[12] paracyclophane (L1), 2,6,9,13-tetraaza[14]paracyclophane (L2), 14,15,17,18-tetramethyl-2,5,8,11-tetraaza[12]paracyclophane (L3) and 16,17,19,20-tetramethyl-2,6,9,13-tetraaza[14]paracyclophane (L4) as a function of pH have been measured. The fully protonated species of each cyclophane gives the highest fluorescence-emission quantum yield. The shapes of the titration curves have been explained by the existence of an electron-transfer quenching effect from a non-protonated amine to the benzene chromophore. This effect is greater for macrocycles in which the first deprotonated amine group is closer to the benzene. The association constants for the interaction of the four fully protonated macrocycles with K3[Co(CN)6] have been measured either by potentiometry or from fluorescence-emission measurements, and increase in the order L3≈ L4 < L1≈ L2. The photoaquation quantum yields of K3[Co(CN)6] have been measured in the presence of the macrocycles L1 and L2, and indicate that three of the CN nitrogens of the complex are involved in adduct formation with the fully protonated macrocycles, as supported by molecular modelling.

Chromophore

Quantum yield

Cyclophane

10.1039/dt9950000993

Cite

Citations (29)

CCDC 1009324: Experimental Crystal Structure Determination

The Cambridge Structural Database (2015)

Laura Acosta-Rueda Estefanía Delgado‐Pinar Javier Pitarch‐Jarque Alexis Rodríguez Salvador Blasco

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Crystal (programming language)

10.5517/cc12w8v2

Cite

Citations (0)

CCDC 2192965: Experimental Crystal Structure Determination

The Cambridge Structural Database (2023)

Valeria Dantignana M. Carmen Pérez-Segura Pau Besalú‐Sala Estefanía Delgado‐Pinar Álvaro Martínez‐Camarena

10.5517/ccdc.csd.cc2clytr

Cite

Citations (0)

CCDC 2192963: Experimental Crystal Structure Determination

The Cambridge Structural Database (2023)

Valeria Dantignana M. Carmen Pérez-Segura Pau Besalú‐Sala Estefanía Delgado‐Pinar Álvaro Martínez‐Camarena

10.5517/ccdc.csd.cc2clyrp

Cite

Citations (0)

CCDC 2192964: Experimental Crystal Structure Determination

The Cambridge Structural Database (2023)

Valeria Dantignana M. Carmen Pérez-Segura Pau Besalú‐Sala Estefanía Delgado‐Pinar Álvaro Martínez‐Camarena

10.5517/ccdc.csd.cc2clysq

Cite

Citations (0)

Receptors for Nucleotides

Supramolecular chemistry (2012)

Enrique García‐España Raquel Belda Jorge González‐García Javier Pitarch Antonio Bianchi

Abstract Recognition and activation of nucleotides by polyammonium receptors constitute an important target in supramolecular chemistry since the very beginning of this field. Nucleotides have three components: (i) the polyphosphate chain, (ii) the sugar moiety, and (iii) the nucleobase, which permit their multipoint binding through attractions between opposite charges, hydrogen bonding, π‐stacking, CH–π interactions, and so on. In this chapter, different receptors for nucleotides, most but not all of them consisting polyamines, are examined, focusing on their molecular structure that enables different binding modes to be operated. Also, a number of examples of nucleotide binding through metal complex formation are presented and discussed. The ATPase and/or kinase activity of abiotic molecules, in particular, of the macrocycle O‐BISDIEN, is briefly introduced. In the last part of the chapter, examples of receptors that are able to selectively sense nucleotides through different operational mechanisms are presented.

Nucleobase

Moiety

Molecular Recognition

Polyphosphate

10.1002/9780470661345.smc066

Cite

Citations (7)

1,10-Dimethyl-1,4,7,10,13,16-hexaazacyclooctadecane L and 1,4,7-trimethyl-1,4,7,10,13,16,19-heptaazacyclohenicosane L1: two new macrocyclic receptors for ATP binding. Synthesis, solution equilibria and the crystal structure of (H₄L)(ClO₄)₄

Journal of the Chemical Society. Perkin transactions II (1994)

Antonio Andrés Carla Bazzicalupi Andrea Bencini Antonio Bianchi Vieri Fusi

The synthesis of two new methylated ligands 1,10-dimethyl-1,4,7,10,13,16-hexaazacyclooctadecane L and 1,4,7-trimethyl-1,4,7,10,13,16,19-heptaazacyclohenicosane L1 is described. Basicity constants and protonation enthalpies of both ligands have been determined by potentiometric and microcalorimetric measurements in 0.15 mol dm–3 NaClO4 at 298.1 K. The protonated forms of these cyclic polyamines bind ATP in solution. The equilibrium constants of the species formed have been determined (0.15 mol dm–3 NaClO4, 298.1 K). The results presented for L and L1 are compared with those previously obtained for the related ligands 1,4,7,10,13,16-hexaazacyclooctadecane, 1,4,7,10,13,16,19-heptaazacyclohenicosane and 1,4,7,13-tetramethyl-1,4,7,10,13,16-hexaazacyclooctadecane. Among these macrocycles Lis a selective receptor for ATP binding.The crystal structure of the compound (H4L)(ClO4)4[space group P21/c, a= 9.257(4), b= 8.600(2). c= 17.990(10)Å, β= 101.74(4)°, V= 1402(1)Å3, Z= 2] shows that the four charged ammonium groups point inside the macrocyclic cavity.

10.1039/p29940002367

Cite

Citations (28)

Thermodynamic and fluorescence emission studies on chemosensors containing anthracene fluorophores. Crystal structure of {[CuL1Cl]Cl}2·2H2O [L1 = N-(3-aminopropyl)-N ′-3-(anthracen-9-ylmethyl)aminopropylethane-1,2-diamine]

Journal of the Chemical Society. Dalton transactions (1999)

Alexandra Bernardo Fernando Piña Beatriu Escuder Enrique García‐España M.L. Godino-Salido

The co-ordination capabilities toward hydrogen ions, Co2+, Ni2+, Cu2+, Zn2+ and Cd2+ of the novel receptor 2,6,9,13-tetraaza[14](9,10)anthracenophane (L) and of its open-chain counterpart N-(3-aminopropyl)-N′-3-(anthracen-9-ylmethyl)aminopropylethane-1,2-diamine (L1) is described. Stepwise protonation constants of the cyclic receptor (L) are lower than those of the open-chain receptor (L1) . Quenching effects of the fluorescence emission occur upon first and second deprotonation of L and upon second deprotonation of L1. Stability constants of the Co2+, Ni2+, Cu2+, Zn2+ and Cd2+ complexes follow the Irving–Williams trend and are intermediate between those of triethylenetetraamine with terminal primary amino groups and those of the α,ω-dibenzylated receptor 1,12-dibenzyl-1,5,8,12-tetraazaciclododecane. Luminescence studies show that complexation of Cu2+ and Ni2+ by L1 yield CHEQ effects (chelation enhanced quenching) while complexation of Zn2+ and Cd2+ produce CHEF effects (chelation enhanced fluorescence). The magnitude of these effects depends on the strength of the co-ordination. Crystals of {[CuL1Cl]Cl}2· 2H2O are triclinic, space group P, with a = 13.307(1), b = 13.305(1), c = 16.538(2) Å, α = 104.94(1), β = 111.67(1), γ = 102.76(1)°, R1 = 0.0885, wR2 = 0.2667. The crystal structure of {[CuL1Cl]Cl}2·2H2O shows a very strongly axially distorted square pyramidal co-ordination geometry in which the Cu2+ cation is co-ordinated by all the nitrogen donors of the receptor and a chloride ion disposed at the apical position of the square pyramid. The asymmetric unit is formed by two slightly different [CuL1Cl]+ cations with an arrangement that shows π-stacking of their anthracene sub-units.

Triclinic crystal system

10.1039/a808649d

Cite

Citations (28)

Thermodynamic, kinetic, and structural study of the ligational properties of the macrobicyclic aza-ligand 4,7,10,17,23-pentamethyl-1,4,7,10,13,17,23-heptaazabicyclo[11.7.5]pentacosane (L1) and of its macrocyclic precursor 1,4,7,13-tetramethyl-1,4,7,10,13,16-hexaazacyclooctadecane (L2). Crystal structure of [Zn(L1)(H2O)](BPh4)2

Inorganic Chemistry (1993)

Andrea Bencini Antonio Bianchi Paolo Dapporto Vieri Fusi Enrique García‐España

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThermodynamic, kinetic, and structural study of the ligational properties of the macrobicyclic aza-ligand 4,7,10,17,23-pentamethyl-1,4,7,10,13,17,23-heptaazabicyclo[11.7.5]pentacosane (L1) and of its macrocyclic precursor 1,4,7,13-tetramethyl-1,4,7,10,13,16-hexaazacyclooctadecane (L2). Crystal structure of [Zn(L1)(H2O)](BPh4)2Andrea Bencini, Antonio Bianchi, Paolo Dapporto, Vieri Fusi, Enrique Garcia-Espana, Mauro Micheloni, Piero Paoletti, Paola Paoli, Agustin Rodriguez, and Barbara ValtancoliCite this: Inorg. Chem. 1993, 32, 12, 2753–2760Publication Date (Print):June 1, 1993Publication History Published online1 May 2002Published inissue 1 June 1993https://pubs.acs.org/doi/10.1021/ic00064a028https://doi.org/10.1021/ic00064a028research-articleACS PublicationsRequest reuse permissionsArticle Views91Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts

10.1021/ic00064a028

Cite

Citations (28)

Triazolopyridines. Part 28. The ring–chain isomerization strategy: triazolopyridine- and triazoloquinoline–pyridine based fluorescence ligands

Tetrahedron (2012)

Rafael Ballesteros‐Garrido Estefanía Delgado‐Pinar Belén Abarca Rafaél Ballesteros Frédéric R. Leroux

Derivative (finance)

10.1016/j.tet.2012.03.029

Cite

Citations (15)