A. Yule

University of London

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S. Skirrow

University of Nottingham

Hagop Bessos

Scottish National Blood Transfusion Service

J P Ackers

London School of Hygiene & Tropical Medicine

B. Andrews

University of Southern Queensland

R.H. BonDurant

University of California, Davis

M C Gellan

University of London

Haima Mylvaganam

Haukeland University Hospital

Charles Lacey

Hull York Medical School

R.H. BonDuran

University of California, Davis

J. A. Carney

Leeds General Infirmary

Cooperative Institutions

University of London

University of California, Davis

London School of Hygiene & Tropical Medicine

University College London

University College Hospital

University of Bergen

Haukeland University Hospital

University of York

Leeds General Infirmary

University of Leeds

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Direct Comparisons between a Radio-Immune Antiglobulin Test, an Enzyme-Linked Antiglobulin Test, and a Haemagglutination Assay: Application to the Screening of Anti-RBC Sera and Monoclonal Antibodies

Vox Sanguinis (1983)

Hagop Bessos A. Yule

Direct comparative studies between a radio-immune antiglobulin test (RIAT), an enzyme-linked antiglobulin test (ELAT) and a haemagglutination assay (HA) were carried out using anti-RBC hybridoma culture supernatants, monoclonal antibodies of established specificity, and immune mouse sera. The direct comparisons revealed that in many cases, RIAT and ELAT were slightly more sensitive than HA for the detection and study of anti-RBC antibodies. RIAT and ELAT detect non-agglutinating antibodies and sub-agglutinating concentrations of antibodies which would be missed if HA is used as the only screening test for hybridoma supernatants.

Coombs test

10.1159/000465321

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Citations (0)

Sensitivity of Trichomonas vaginalis, Tritrichomonas foetus and Giardia intestinalis to bacitracin and its zinc salt in vitro

Transactions of the Royal Society of Tropical Medicine and Hygiene (1994)

B. Andrews Haima Mylvaganam A. Yule

The activity of bacitracin in vitro against Giardia intestinalis, Trichomonas vaginalis and Tritrichomonas foetus was enhanced 5-10 times by equimolar concentrations of zinc. Bacitracin and bacitracin zinc activity was tolerant to either aerobic or anaerobic culture conditions and equally effective against T. vaginalis isolates sensitive or insensitive to metronidazole. This enhancement was not due to zinc toxicity and was zinc dose dependent.

Tritrichomonas foetus

Bacitracin

Trichomoniasis

Giardia

Trichomonas

10.1016/0035-9203(94)90239-9

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Citations (16)

Development and preliminary assessment of a polyclonal antibody-based enzyme immunoassay for the detection of Tritrichomonas foetus antigen in breeding cattle

Veterinary Parasitology (1989)

A. Yule S. Skirrow J Staats R.H. BonDurant

Tritrichomonas foetus

Polyclonal antibodies

10.1016/0304-4017(89)90026-5

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Citations (10)

Detection of Trichomonas vaginalis antigen in women by enzyme immunoassay.

Journal of Clinical Pathology (1987)

A. Yule M C Gellan J D Oriel J P Ackers

An enzyme immunoassay (EIA) was developed for the detection of Trichomonas vaginalis antigen in vaginal swabs. Four hundred and eighty two women attending a sexually transmitted disease (STD) clinic were tested; 44 (9.1%) were positive by culture, 32 (6.6%) were positive by wet film examination, and 54 (11.2%) were considered to be positive for trichomonal antigen by EIA. Taking culture as the reference method, the EIA had a sensitivity of 93.2% and a specificity of 97.5%. The predictive value of a positive test was 82% and that of a negative test was 99.3%.

Trichomonas

Trichomonas Vaginitis

False Negative Reactions

10.1136/jcp.40.5.566

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Citations (25)

Direct Comparisons between a Radio‐Immune Antiglobulin Test, an Enzyme‐Linked Antiglobulin Test, and a Haemagglutination Assay: Application to the Screening of Anti‐RBC Sera and Monoclonal Antibodies

Vox Sanguinis (1983)

Hagop Bessos A. Yule

Abstract. Direct comparative studies between a radio‐immune antiglobulin test (RIAT), an enzyme‐linked antiglobulin test (ELAT) and a haemagglutination assay (HA) were carried out using anti‐RBC hybridoma culture supernatants, monoclonal antibodies of established specificity, and immune mouse sera. The direct comparisons revealed that in many cases, RIAT and ELAT were slightly more sensitive than HA for the detection and study of anti‐RBC antibodies. RIAT and ELAT detect non‐agglutinating antibodies and sub‐agglutinating concentrations of antibodies which would be missed if HA is used as the only screening test for hybridoma supernatants.

Coombs test

10.1111/j.1423-0410.1983.tb04484.x

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Citations (5)

New rapid latex agglutination test for diagnosing Trichomonas vaginalis infection.

Journal of Clinical Pathology (1988)

J. A. Carney P. Unadkat A. Yule R Rajakumar Charles Lacey

A newly developed latex agglutination test for Trichomonas vaginalis infection was compared for sensitivity, specificity, efficiency, and positive and negative predictive values with microscopy, culture, and an enzyme linked immunosorbent assay (ELISA) in the diagnosis of 395 women attending a genitourinary medicine clinic. T vaginalis infection was diagnosed in 42 (11%) women. The sensitivities of both the latex agglutination test and the ELISA were 95% compared with 74% for microscopy and 76% for culture. The latex test was specific and showed no cross reaction with a wide range of other genital tract infections. The latex agglutination test can detect antigen in both soluble and insoluble forms, and as it is simple to perform, can be undertaken during routine examination without recourse to special equipment or training. Further evaluation is required.

Latex fixation test

Agglutination (biology)

Trichomonas Vaginitis

Trichomonas

10.1136/jcp.41.7.806

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Citations (33)

Bovine Trichomoniasis

Parasitology Today (1989)

A. Yule S. Skirrow R.H. BonDuran

Trichomoniasis

Tritrichomonas foetus

Trichomonas

10.1016/0169-4758(89)90298-6

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Citations (106)