Rosa Pedata

University of Naples Federico II

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Angela Dinatale

Azienda Ospedaliera Universitaria Policlinico "G. Martino"

Santina Ermito

University of Bergamo

Alessandro Cavaliere

Sapienza University of Rome

Sabina Carrara

Sapienza University of Rome

Elisa Pappalardo

Azienda di Rilievo Nazionale ed Alta Specializzazione

Alessia Mammaro

Policlinico Tor Vergata

Stefania Recupero

University of Messina

Alessandra Cacciatore

Centro di Riferimento Oncologico della Basilicata

Laura Imbruglia

Azienda Socio Sanitaria Territoriale Bergamo Est

Manuela Chiara Accardi

Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele

Cooperative Institutions

Sapienza University of Rome

University of Messina

Azienda Ospedaliera Universitaria Policlinico "G. Martino"

University of Catania

Istituti di Ricovero e Cura a Carattere Scientifico

University of Bergamo

Azienda di Rilievo Nazionale ed Alta Specializzazione

University of Oxford

High Throughput Biology (United States)

Johns Hopkins University

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The management of molar pregnancy

Alessandro Cavaliere Santina Ermito Angela Dinatale Rosa Pedata

Gestational Trophoblastic Disease (GTD) originates from placental tissue and is among the rare human tumors that can be cured even in the presence of widespread metastases. GTD include a spectrum of interrelated tumors including complete and partial hydatidiform mole, invasive mole, choriocarcinoma, and placental site trophoblastic tumor, that have different propensities for local invasion and spread. Although most GTD develop after a mole, they can follow any antecedent pregnancy. Transvaginal ultrasound, routinary dosage of beta-hCG and current approaches to chemotherapy, let most women with malignant gestational trophoblastic disease to be cured and their reproductive function preserved.

Partial Hydatidiform Mole

Molar Pregnancy

Gestational Trophoblastic Disease

Mole

Trophoblastic Tumor

Trophoblastic neoplasm

Trophoblast

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Citations (33)

Hypertensive disorders of pregnancy.

PubMed (2009)

Alessia Mammaro Sabina Carrara Alessandro Cavaliere Santina Ermito Angela Dinatale

Hypertension is the most common medical problem encountered during pregnancy, complicating 2-3% of pregnancies. Hypertensive disorders during pregnancy are classified into 4 categories, as recommended by the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy: 1) chronic hypertension, 2) preeclampsia-eclampsia, 3) preeclampsia superimposed on chronic hypertension, and 4) gestational hypertension (transient hypertension of pregnancy or chronic hypertension identified in the latter half of pregnancy) (1). This terminology is preferred over the older but widely used term pregnancy-induced hypertension (PIH) because it is more precise.

Gestational hypertension

Chronic hypertension

Hypertension in Pregnancy

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Citations (113)

Fetal lung lesions diagnosis: the crucial role of ultrasonography.

PubMed (2009)

Rosa Pedata M Palermo Monica R. Maiello N Esposito Santina Ermito

Fetal lung lesions may cause significant effects of mass and may evolve into a non-immune hydrops and lead to the death of the fetus or the child. Treatment options for these severely affected infants are constantly evolving. The widespread use of ultrasound in prenatal diagnosis, in tertiary center like ours, allows us to identify the fetus, including lung lesions more 'small. Prenatal diagnosis and possible therapeutic intervention in the immediate prenatal or postnatal period has significantly changed the quality of life and the survival of fetuses and infants, especially those who were completely asymptomatic at birth.Object of our interest is the pulmonary sequestration and congenital pulmonary malformation is the second in order of frequency, with an incidence between 0.15% and 6.4% of cases.

Prenatal ultrasound

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Citations (4)

Abnormal skull findings in neural tube defects.

PubMed (2009)

Laura Imbruglia Alessandra Cacciatore Sabina Carrara Stefania Recupero Tindara La Galia

The human neural tube develops and closes during the third and fourth week after conception and is normally completed by 28 days post-conception. Malformations, knows as neural tube defects, occure, when the normal closure process fails. Several clinical types of neural tube defects are recognized, anencefaly and spina bifida being the most common. Such malformations are generally associated with cranial abnormlities.

Neural tube defect

Closure (psychology)

Neural Activity

Human skull

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Citations (4)

Management of molar pregnancy.

PubMed (2009)

Alessandro Cavaliere Santina Ermito Angela Dinatale Rosa Pedata

Gestational Trophoblastic Disease (GTD) originates from placental tissue and is among the rare human tumors that can be cured even in the presence of widespread metastases. GTD include a spectrum of interrelated tumors including complete and partial hydatidiform mole, invasive mole, choriocarcinoma, and placental site trophoblastic tumor, that have different propensities for local invasion and spread. Although most GTD develop after a mole, they can follow any antecedent pregnancy.Transvaginal ultrasound, routinary dosage of beta-hCG and current approaches to chemotherapy, let most women with malignant gestational trophoblastic disease to be cured and their reproductive function preserved.

Partial Hydatidiform Mole

Molar Pregnancy

Gestational Trophoblastic Disease

Mole

Trophoblastic Tumor

Gestational trophoblastic neoplasia

Trophoblastic neoplasm

Trophoblast

Source

Cite

Citations (30)