Jesús Herrero

Universidad de Salamanca

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R. Ruiz Beltrán

Complejo Hospitalario de Salamanca

Jorge Portugal

National Center for Injury Prevention and Control

Vicente Vicente

Instituto de Salud Carlos III

N. Riba Pagès

A. Herrero San Martín

University of South Carolina

Rosa M. Badía

Barcelona Supercomputing Center

Cándido Martín‐Luengo

Universidad de Salamanca

Francisco Sanz

Hospital General Universitario De Valencia

María Hernández

Clinica Universidad de Navarra

M. Bea Sintes

Cooperative Institutions

Universidad de Salamanca

Instituto de Salud Carlos III

Centro de Investigación Biomédica en Red

Complejo Hospitalario de Salamanca

Instituto de Investigación Biomédica de Salamanca

Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública

Institut d'Investigació Biomédica de Bellvitge

Universidad Complutense de Madrid

Universitat de Barcelona

Centre for Biomedical Network Research on Rare Diseases

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Relationship between the Duration of the Basal QRS Complex and Electrical Therapies for Ventricular Tachycardias among ICD Patients

Pacing and Clinical Electrophysiology (2009)

Javier Jiménez‐Candil M. Martínez Ruiz Jesús Herrero Víctor León Ana Martín‐Garcia

Background: In implantable cardioverter-defibrillators (ICD) patients, the duration of the basal QRS complex (QRSd) is not associated with a greater risk of developing ventricular tachyarrhythmias. QRSd could be inversely related to the effectiveness of antitachycardia pacing (ATP) because it may be associated with longer conduction times of the paced-impulses and hence, with a greater propensity to require shocks to terminate ventricular tachycardias (VTs). Methods: We followed 216 ICD patients (pacing site: right ventricular apex; QRSd ≤ 100: 34%) for 21 ± 12 months. ICD programming was standardized. QRSd was determined on the electrocardiogram (50 mm/s) at device implantation. Results: Five hundred and fifty-one VTs (cycle length: 329 ± 35 ms) occurred in 67 patients (36% had a QRSd ≤ 100 ms). ATP terminated 86% of VTs and 11% needed shocks. Mean ATP efficiency per patient was 83%. QRSd was significantly correlated with the probability of successful ATP (C-coefficient: 0.66), the best cut-off point being 100 (sensitivity and specificity of 91% and 49%). Patients with QRSd ≤ 100 had a higher ATP effectiveness (98% vs 75%; P = 0.003) and fewer VTs terminated by shocks (1% vs 23%; P = 0.003). By logistic regression, QRSd > 100 remained as an independent predictor of receiving shocks to terminate VTs (P = 0.01). According to Kaplan-Meier analysis, the occurrence of VTs was similar regardless of the QRSd (30% vs 38%; P = 0.2), but the incidence of shock due to VTs was higher in patients with a QRSd > 100 (19% vs 7%; P = 0.01). Conclusion: Since QRSd is a negative and independent predictor of effective ATP, ICD patients with QRSd > 100 ms require shocks more frequently to terminate VTs. (PACE 2010; 596–604)

Basal (medicine)

10.1111/j.1540-8159.2009.02648.x

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Citations (11)

Severe forms of mediterranean exanthematic fever. A prospective analysis of 71 patients

R. Ruiz Beltrán Jesús Herrero Almudena Sánchez

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Vascular Permeability in Boutonneuse Fever

The Journal of Infectious Diseases (1984)

Rut Menjón Ruiz Jesús Herrero A. M. Martin Francisco Sanz Ana Mateos

Boutonneuse fever

Vascular permeability

10.1093/infdis/149.6.1036

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Citations (12)

20163. INSOMNIO FATAL ESPORÁDICO: CASO CLÍNICO

Neurology Perspectives (2024)

N. Riba Pagès I. Abad Inchaurrondo V. Silva Ordovás Jesús Herrero Miquel Pujol

10.1016/s2667-0496(24)01027-5

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Kinin-Prekallikrein System in Mediterranean Spotted Fever

The Journal of Infectious Diseases (1986)

Vicente Vicente Adrián Alegre Richard Ruiz Jesús Herrero Jorge Portugal

Journal Article Kinin-Prekallikrein System in Mediterranean Spotted Fever Get access V. Vicente, V. Vicente Department of Medicine, University Hospital, University of Salamanca, Spain Please address requests for reprints to Dr. Vicente, Division of Haematology, Hospital Clinico, Salamanca 37007, Spain Search for other works by this author on: Oxford Academic PubMed Google Scholar A. Alegre, A. Alegre Department of Medicine, University Hospital, University of Salamanca, Spain Search for other works by this author on: Oxford Academic PubMed Google Scholar R. Ruiz, R. Ruiz Department of Medicine, University Hospital, University of Salamanca, Spain Search for other works by this author on: Oxford Academic PubMed Google Scholar J. I. Herrero, J. I. Herrero Department of Medicine, University Hospital, University of Salamanca, Spain Search for other works by this author on: Oxford Academic PubMed Google Scholar J. Portugal, J. Portugal Department of Medicine, University Hospital, University of Salamanca, Spain Search for other works by this author on: Oxford Academic PubMed Google Scholar I. Alberca I. Alberca Department of Medicine, University Hospital, University of Salamanca, Spain Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 154, Issue 3, September 1986, Page 541, https://doi.org/10.1093/infdis/154.3.541 Published: 01 September 1986

10.1093/infdis/154.3.541

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Deleterious effect of trimethoprim-sulfamethoxazole in Mediterranean spotted fever

Antimicrobial Agents and Chemotherapy (1992)

R. Ruiz Beltrán Jesús Herrero

and Drancourt have recently published an update of antimicrobial therapy of rickettsial diseases in Antimicro- bialAgents and Chemotherapy (6).The authors cite some of our research in the treatment of Mediterranean spotted fever (MSF).We consider it of interest to broaden the reference that mentions the inefficacy of trimethoprim-sulfamethoxazole (TS) for treating this rickettsiosis.MSF is a tick-transmitted infectious disease caused by Rickettsia cononii, a gram-negative, strictly intracellular bacterium belonging to the spotted fever group of rickett- siae.MSF used to be considered a mild disease, but in the 216 patients we have studied, infections in 5% evolved into a severe form and 2.7% of the patients died.Since previous

Sulfamethoxazole

Trimethoprim

10.1128/aac.36.6.1342

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Citations (40)

PersonalityDisorders Associated W ithAddictive Behaviour: Examining the Influence ofthe DrugAddiction Course and its Implications

Jesús Herrero

Comorbidityis a central aspect in current psychopathology.In the field ofdrugaddictions, different studies have shown a high prevalence ofpersonalitydisorders in this population.The goal ofthe present investigation was centered on analyzing the relation between different personalitydisorders and the consumption duration.The subjects were 1094 drugaddicts that were evaluated in a rehabilitation and treatment unit (Proyecto Hombre’s Therapeutic Community).Personalitydisorders were ascertained usingthe M illon Clinical M ultiaxial Inventory IISpanishversion (MCMI-II).The difficulties ofstudyingthe relation amongduration ofaddiction and personality are presented, and clinical implications ofstudyfindings are discussed.

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Evaluation of ciprofloxacin and doxycycline in the treatment of mediterranean spotted fever

European Journal of Clinical Microbiology & Infectious Diseases (1992)

R. Ruiz Beltrán Jesús Herrero

Medical microbiology

10.1007/bf01961857

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Citations (59)

Morbilidad psiquiátrica en consumidores de cocaína y heroína reclutados en la comunidad Psychiatric morbidity among cocaine and heroin users in the community

Silvia Tortajada Jesús Herrero Antònia Domingo‐Salvany Gemma Molist Gregorio Barrio

Coca

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Naturally Acquired Immunity: A Means of Resistance to Mediterranean Spotted Fever?

The Journal of Infectious Diseases (1991)

Jesús Herrero R. Ruiz Beltrán Almudena Sánchez-Gómez

Figure l.Interleukin-2 (IL-2) enables human herpesvirus-S (HHV-6) replication in monoclonal antibody 64.I-treated mature thyrnocytes.Cultures were photographed 7 days after infection.PHA.phytohemagglutinin.Triggering through the T cell receptor complex is thought to represent the natural mode of activation ofT cells by antigens.The inability ofthymocytes to synthesize IL-2 as a result ofCD3 cross-linking by MAb 64.1 is advantageous, since this system can be used for identifying discrete stages of the interaction between HHV-6 and its host cells.

Acquired resistance

10.1093/infdis/164.3.618

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Citations (2)