Antonio Martino

Magna Graecia University

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Giovanni Cammarota

Agostino Gemelli University Polyclinic

Roberto Petri

Universidade Federal do Rio de Janeiro

Rossella Cianci

Università Cattolica del Sacro Cuore

Antonio Gasbarrini

Università Cattolica del Sacro Cuore

Massimo Vecchiato

University of Udine

Antonio Ziccarelli

Ospedale Santa Maria della Misericordia di Udine

Renato Capasso

University of Naples Federico II

Paola Valentino

Magna Graecia University

Gautam Maharajan

Marianna Iorio

University of Naples Federico II

Cooperative Institutions

Istituti di Ricovero e Cura a Carattere Scientifico

152

University of Naples Federico II

137

University of Siena

118

Sapienza University of Rome

University of Campania "Luigi Vanvitelli"

Università Cattolica del Sacro Cuore

Agostino Gemelli University Polyclinic

Federico II University Hospital

Collaborative Group (United States)

Vita-Salute San Raffaele University

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Rectus sheath hematoma, rare condition, difficult diagnosis and multidisciplinary treatment: report of 5 cases

BMC Geriatrics (2011)

Antonio Martino Ciro De Martino Anna Pisapia Gautam Maharajan Marco Evangelista

Background Rectus sheath hematoma is a rare condition. It encompasses a wide spectrum of severity (self-limiting to fatal) depending on its size, etiology, and the development of complications. It has multiple possible etiologies including, frequently, coagulation disorders or anticoagulation therapy. It enters into the differential diagnosis of abdominal pain but it’s frequently difficult to diagnose and radiological imaging is often required. Methods We report a series of five patients that came to our hospital within a 8-month period. The patients were between 63 to 78 years old. One of them was in therapy with warfarin, one was in therapy with acetilsaliciliate and clopidogrel and in an another patient, a coagulation disorder was detected. Diagnosis was suspected in all cases by clinical exam and ultrasonography, but CTscan was necessary in three cases. All patients underwent conservative treatment, mainly pain relief and rest. In two cases blood transfusion was performed and in two cases clotting abnormalities were corrected with vitamin K and fresh frozen plasma. After being discharged, patients were followed up on as outpatients. Results All patients were treated conservatively. Average hospitalization was 10 days (range 5-17 days). The patient healed within three months at least. One patient developed infection of the hematoma and was treated with ultrasound-guided aspiration and antibiotics. Conclusions Rectus sheath hematoma is a rare but important entity in the differential diagnosis of abdominal pain. Interdisciplinary awareness of this condition is essential, as it is frequently difficult to diagnose, leading to delay in treatment or unneeded surgery. CT-scan is the gold-standard investigation. Treatment options are variable and include conservative treatment, intravascular embolization and surgery. Frequently an interdisciplinary team approach is needed.

Multidisciplinary team

10.1186/1471-2318-11-s1-a29

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Citations (1)

Soil washing with solutions of humic substances from manure compost removes heavy metal contaminants as a function of humic molecular composition

Chemosphere (2019)

Alessandro Piccolo Riccardo Spaccini Antonio Martino Francesco Scognamiglio Vincenzo Di Meo

Amendment

10.1016/j.chemosphere.2019.03.019

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Citations (98)

Recovery and characterization of the humate-like salified polymeric organic fraction (lignimerin) from Kraft cellulose mill wastewater

Chemosphere (2007)

M.C. Díez Olga Rubilar Mara Cea Rodrigo Navia Antonio Martino

Paper mill

Fraction (chemistry)

Characterization

10.1016/j.chemosphere.2007.03.013

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Citations (7)

High flow nasal oxygen vs. conventional oxygen therapy over respiratory oxygenation index after esophagectomy: an observational study

Journal of Thoracic Disease (2024)

Cristian Deana Massimo Vecchiato Francesco Bellocchio Annarita Tullio Antonio Martino

Cristian Deana, Massimo Vecchiato, Francesco Bellocchio, Annarita Tullio, Antonio Martino, Antonio Ziccarelli, Vincenzo Patruno, Marika Pascolo, Flavio Bassi, Marta Pontoni, Paola Raimondi, Lorenzo Cereser, Luigi Vetrugno, Roberto Petri, Alessandro Uzzau

Esophagectomy

Oxygen therapy

10.21037/jtd-23-1176

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Citations (2)

Nifedipine for local use in conservative treatment of anal fissures

Diseases of the Colon & Rectum (1999)

Carmine Antropoli Pasquale Perrotti Mauro Rubino Antonio Martino Giovanni Stefano

PURPOSE: This study was performed according to a prospective, randomized, double-blind, multicenter design. The aim was to test the efficacy of local application of nifedipine gela in healing acute anal fissure by relaxing the internal anal sphincter. METHODS: Two hundred eighty-three patients who gave informed consent were recruited; they received a clinical examination. A questionnaire to evaluate the symptoms and the pain was administered, and a proctoscopy and anorectal manometry were performed. Patients treated with nifedipine (n=141) used topical 0.2 percent nifedipine gel every 12 hours for three weeks. The control group, consisting of 142 patients, received topical 1 percent lidocaine and 1 percent hydrocortisone acetate gel during therapy. Manometry was performed before and on Days 14 and 21. Anal pressures were measured by recording resting and squeeze pressures. RESULTS: Results obtained were as follows: total remission from acute anal fissure was achieved after 21 days of therapy in 95 percent of the nifedipine-treated patients (P <0.01), as opposed to 50 percent of the controls (P <0.01), and previously elevated maximum resting anal pressures decreased from a mean value ± standard deviation of 72.5±10.07 mmHg to 50.5±10.03 mmHg in the nifedipine group. This represents a mean reduction of 30 percent (P <0.01). We also observed a significant decrease in squeeze pressures in nifedipine-treated patients (from a mean ± standard deviation of 130.5±19.25 mmHg to 108.5±18.55 mmHg, a mean reduction of 16.8 percent; P <0.01). No changes in anal pressures were observed in the control group. We did not observe any systemic side effect or significant anorectal bleeding in patients treated with nifedipine. CONCLUSIONS: Our study clearly demonstrates that the therapeutic use of nifedipine, which at present is used only in cardiovascular pathologies, should be extended with local use to the conservative treatment of anal fissures.

Anorectal manometry

10.1007/bf02236693

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Citations (148)

Nitrogen metabolism during liver regeneration

Biochimica et Biophysica Acta (BBA) - General Subjects (1993)

Marco Lorenzi Antonio Martino Filippo Carlucci Antonella Tabucchi Brunetta Porcelli

Allantoin

Alanine

Gluconeogenesis

Isoleucine

10.1016/0304-4165(93)90072-g