Siyu Song

University of British Columbia

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Fuchao Yu

Kunming University of Science and Technology

Zhilai Zhang

Kunming University of Science and Technology

Menglin Peng

Kunming University of Science and Technology

Zhichao Pei

Northwest A&F University

Cara H. Haney

University of British Columbia

Yuxin Pei

Northwest A&F University

Yongchao Wang

Yunnan Normal University

Mingshuai Zhang

Kunming University of Science and Technology

Yuanzheng Wei

Kunming University of Science and Technology

Yanhong Wang

North University of China

Cooperative Institutions

Chinese Academy of Sciences

University of Chinese Academy of Sciences

Kunming University of Science and Technology

University of British Columbia

Northwest A&F University

Fudan University

Central South University

Peking University

Dalian University of Technology

Huazhong University of Science and Technology

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Mechanical Properties and Microstructure of Mechanical Sand Concrete at High Temperature based on Electron Microscopy

Journal of Physics Conference Series (2023)

Siyu Song Zhongbo Tang Jiayuan Zhang Hao Li Xiujiang Yang

Abstract For sustainable development, sand-mixed concrete has been paid more and more attention by researchers. In order to study the mechanical properties of sand-gravel concrete, five temperature levels of natural cooling and water cooling were considered, and the mechanical properties of sand-stone concrete after high temperature were tested.. In order to study the mechanical properties of desert sand concrete after high temperature, this paper designs a single factor test with the replacement rate of desert sand as the variable. Five temperature levels are considered, and natural cooling and watering cooling are adopted to test the mechanical properties of desert sand concrete after high temperature. The influences of temperature, desert sand replacement rate, cooling method and fly ash content on compressive strength, axial compressive strength and static compressive elastic modulus of desert sand concrete after high temperature were analyzed, and the deterioration model of strength and elastic modulus of desert sand concrete after high temperature was established. From high temperature post-voltage voltage specimen sampling, X-ray diffraction (XRD) analysis and scanning electron microscopy (SEM) observation, from the micro level desert sand concrete after high temperature macro performance deterioration mechanism to explain.

Properties of concrete

10.1088/1742-6596/2510/1/012024

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Citations (0)

Oriented and reversible immobilization of His-tagged proteins on two- and three-dimensional surfaces for study of protein–protein interactions by a QCM biosensor

Sensors and Actuators B Chemical (2015)

Xueming Li Siyu Song Yuxin Pei Hai Dong Teodor Aastrup

Quartz Crystal Microbalance

Surface protein

Protein crystallization

10.1016/j.snb.2015.10.096

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Citations (20)

Plasmonic Focusing in Nanostructures

Plasmonics (2014)

Jie Li Chaojie Yang Jiaming Li Ziwei Li Shuai Zu

Plasmonic lens

Ray

Nanophotonics

10.1007/s11468-014-9692-5

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Citations (8)

NBS-Mediated C(sp2)-H Bond Chlorination of Enaminones: Using DCE as Chlorine Source

International Journal of Molecular Sciences (2024)

Menglin Peng Yunhua Xie Siyu Song Zhilai Zhang Yuanzheng Wei

Commercial DCE is excavated as both a "Cl" source and a solvent for the vinyl C(sp

10.3390/ijms252212073

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Natural products targeting AMPK signaling pathway therapy, diabetes mellitus and its complications

Frontiers in Pharmacology (2025)

Min Li Lu Ding L. Cao Zepeng Zhang Xueyan Li

Diabetes mellitus (DM) ranks among the most prevalent chronic metabolic diseases, characterized primarily by a persistent elevation in blood glucose levels. This condition typically stems from either insufficient insulin secretion or a functional defect in the insulin itself. Clinically, diabetes is primarily classified into type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM), with T2DM comprising nearly 90% of all diagnosed cases. Notably, the global incidence of T2DM has surged dramatically over recent decades. The adenylate-activated protein kinase (AMPK) signaling pathway is crucial in regulating cellular energy metabolism, marking it as a significant therapeutic target for diabetes and related complications. Natural products, characterized by their diverse origins, multifaceted bioactivities, and relative safety, hold considerable promise in modulating the AMPK pathway. This review article explores the advances in research on natural products that target the AMPK signaling pathway, aiming to inform the development of innovative antidiabetic therapies.

10.3389/fphar.2025.1534634

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Construction of 1,4-Dihydropyridines: The Evolution of C4 Source

Topics in Current Chemistry (2023)

Siyu Song Yongchao Wang Fuchao Yu

Synthon

DHPS

Broad spectrum

10.1007/s41061-023-00440-x

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Citations (7)

Nbs-Mediated C(Sp2)-H Bond Chlorination of Enaminones: Using Dce as Chlorine Source

Fuchao Yu Menglin Peng Yunhua Xie Siyu Song Zhilai Zhang

10.2139/ssrn.4952016

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[Major blood vessel excision and reconstruction in the treatment of retroperitoneal neoplasms].

PubMed (1998)

Wei Zheng Siyu Song F Liang

To summarize the experience in the treatment of retroperitoneal tumors involving major blood vessels.Twenty five cases with retroperitoneal tumors involving major blood vessels were treated by excision of the tumor and the major blood vessel involved followed by vascular reconstruction.After a careful preoperative evaluation and necessary preparation, the tumor together with the involved blood vessels in all patients are successfully resected and the severed major blood vessels reconstructed. There was no operative death.Retroperitoneal neoplasm involving major blood vessels is not a contraindication for surgical resection. The tumor and the involved vessel can be removed en bloc followed by vascular reconstruction. The risk of local tumor recurrence can thus be minimized and better survival achieved.

Contraindication

Retroperitoneal space

Surgical oncology

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QCM Biosensor Based on Polydopamine Surface for Real-Time Analysis of the Binding Kinetics of Protein-Protein Interactions

Polymers (2017)

Chunli Wu Xueming Li Siyu Song Yuxin Pei Lili Guo

A quartz crystal microbalance (QCM) biosensor based on polydopamine (PDA) surface was developed for real-time analysis of the binding kinetics of protein-protein interactions. The biosensor was fabricated by simply immersing the gold sensor chip into an aqueous dopamine solution at pH 8.5 leading to a spontaneous deposition of PDA film onto the sensor chip surface, which was followed by incubation with the protein to immobilize it onto the PDA-coated sensor chip surface via Michael addition and/or Schiff base reactions. In this paper, the interaction between monoclonal anti-myoglobin 7005 antibody (IgG1) and its antigen human cardiac myoglobin was used as a model system for real-time analysis of biomolecule interactions on the biosensor surface. The kinetic parameters of the interaction between anti-myoglobin 7005 and myoglobin were studied on the biosensor surface, which were consistent with the results obtained via amine coupling. The biosensor based on PDA surface has excellent regenerability, reproducibility, and specificity. Compared with the most frequently/typically used amine coupling method for immobilization of proteins on carboxylated substrates, the modification methodology presented in this paper is simple, mild and is not subjected to the limitations of the isoelectric point (pI) of the protein. In addition, the PDA biosensor chip can be easily reused, which makes QCM biosensor analysis more efficient and cost effective.

Quartz Crystal Microbalance

Biomolecule

Receptor–ligand kinetics

Surface Modification

10.3390/polym9100482

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Citations (18)

Influence of Particle Size in Talc Suppression by a Galactomannan Depressant

Minerals (2018)

Zhixiang Chen Guohua Gu Shuangke Li Siyu Song Chongqing Wang

Flotation behavior of different sizes of particles may follow different trends. The influence of particle size in talc suppression by a depressant galactomannan was studied in this research. The flotation response and mechanism were examined by flotation tests, modified flotation rate constant and entrainment recovery calculation, laser particle size experiments, adsorption tests, and advancing contact angle measurement as well as scanning electron microscopy (SEM) and energy dispersive X-ray spectrometry (EDS). The maximum recovery increased with particle size increases in the absence of galactomannan FPY (Fenugreek polysaccharide). The obviously suppressed effect was observed for the size fraction of −74 + 38 μm after reacting with FPY, but low efficiency was received for −38 μm and −10 μm, respectively. Laser particle size analysis indicated that the FPY has a certain function for the flocculation of fine particles. It is beneficial for reducing recovery by entrainment. EDS and advancing contact angle test results showed that the difference in contact angles probably is a result of genuine differences in the quantity of O and Mg bearing surface species, while the contact angle varied with particle size fraction in the absence of FPY. Adsorption and SEM test results demonstrated that in the case of −74 + 38 μm, the depressant adsorption density on the mineral surface is higher than the other two size fractions. On the whole, FPY probably is not enough of a depressant for talc suppression.

Depressant

Talc

Particle (ecology)

10.3390/min8040122

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Citations (8)