Mary Wu Chang

University of Connecticut

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Co-Authors

Seth J. Orlow

New York University

Hideko Kamino

New York University

Andrea L. Zaenglein

Penn State Milton S. Hershey Medical Center

Helen T. Shin

Hackensack Meridian Health

Melinda Jen

Children's Hospital of Philadelphia

Julie V. Schaffer

Hackensack University Medical Center

Ilona J. Frieden

University of California, San Francisco

Tor Shwayder

Henry Ford Hospital

Sarah Kamsiah Zemlok

University of Connecticut

Lorin A. Bibb

Vanderbilt University Medical Center

Cooperative Institutions

Harvard University

Boston Children's Hospital

Children's Hospital of Philadelphia

American Academy of Dermatology

University of Pennsylvania

New York University

UConn Health

Boston Children's Museum

University of California, San Francisco

Medical University of South Carolina

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Research Field

Vitiligo: A Practical Review

Journal watch (2009)

Mary Wu Chang

The authors of this clinical practice article summarize the subtypes, natural history, and treatment of vitiligo, a common and disfiguring disease marked by loss of epidermal melanocytes. Vitiligo has a worldwide prevalence of 0.5%; half of all patients present before 20 years of age. Diagnosis is clinically based, with Wood’s lamp examination helpful in patients with lighter skin. Skin biopsy is rarely needed. Nonsegmental vitiligo (NSV; aka generalized vitiligo) and segmental vitiligo (SV) differ clinically and in their responsiveness to treatment. SV is …

Vitiligo

AKA

Clinical Practice

10.1056/jd200901070000001

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Citations (0)

Don't Just Eat Dirt, Breathe Dirt!

Journal watch (2011)

Mary Wu Chang

Studies have shown that growing up on a farm is associated with reduced risk for asthma, possibly through stimulation of the innate immune system in

Dirt

10.1056/jd201104010000001

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Safety of Propranolol for Severe Infantile Hemangioma: A Prospective Cohort Study

Journal watch (2016)

Mary Wu Chang

Infantile hemangioma (IH) is a common, benign vascular tumor characterized by rapid proliferation shortly after birth and eventual spontaneous

Infantile hemangioma

10.1056/nejm-jw.na40281

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Etanercept for Pediatric Psoriasis

Journal watch (2006)

Mary Wu Chang

Psoriasis is common in children, but most systemic medications have not been systematically studied in the pediatric population. Etanercept, a soluble

10.1056/jd200604250000002

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A Randomized, Controlled Trial of Oral Propranolol for Infantile Hemangioma

Journal watch (2015)

Mary Wu Chang

Infantile hemangiomas (IH) affect up to 10% of infants. A rapid proliferative phase is followed by slow spontaneous involution. Approximately 12% of IH

Infantile hemangioma

10.1056/nejm-jw.na36986

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Citations (0)

Updated Classification of Hemangiomas and Other Vascular Anomalies

Lymphatic Research and Biology (2003)

Mary Wu Chang

Vascular anomalies comprise a widely heterogenous group of tumors and malformations. Great confusion has arisen because of the term hemangioma has been and is continued to be used to represent a multitude of vascular entities. This review presents the updated classification of vascular anomalies with the goal of clarifying the term hemangioma. In addition, newer clinical concepts in hemangiomas and other vascular tumors is presented. Hemangioma subtypes and hemangioma variants are also discussed, and a brief review of pyogenic granuloma and Kaposiform hemangioendothelioma is provided. Finally, the immunohistochemical marker GLUT1 is reviewed, a marker that heralds a new era in vascular anomalies research.

Vascular Tumors

Confusion

Pyogenic granuloma

Hemangioendothelioma

10.1089/153968503322758067

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Citations (75)

“Acquired Port-Wine Stains” Can Morph into Morphea

Journal watch (2011)

Mary Wu Chang

Port-wine stains (PWSs) are common birthmarks caused by capillary malformations of the skin. They present at birth as flat, pink, red, or maroon

Port wine

Morphea

10.1056/jd201104010000002

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Citations (0)

Does Isotretinoin Increase the Risk for Celiac Disease

Journal watch (2014)

Mary Wu Chang

The vitamin A metabolite retinoic acid plays an important role in the immune regulation of the gut and seems to promote inflammatory responses to

Isotretinoin

10.1056/nejm-jw.na35452

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Nevus Sebaceus: To Excise or Not to Excise?

Journal watch (2014)

Mary Wu Chang

Nevus sebaceus (NS) is a common hamartomatous birthmark found in up to 1% of dermatology patients. NS is usually noted on the head and neck region at

Excise

10.1056/nejm-jw.na33257

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Vincristine for Kasabach-Merritt Phenomenon

Journal watch (2003)

Mary Wu Chang

Kasabach-Merritt phenomenon (KMP) is characterized by profound thrombocytopenia, consumptive coagulopathy, and hemolytic anemia. KMP is not associated with infantile hemangioma but is triggered in most cases by a growing vascular tumor, usually kaposiform hemangioendothelioma or tufted angioma. The mortality rate is approximately 30%, management is difficult, and an optimal treatment has not been identified. The literature has been …

Consumptive Coagulopathy

Infantile hemangioma

Kasabach–Merritt syndrome

Vascular Tumors

Microangiopathic hemolytic anemia

10.1056/jd200306250000009

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