A cardiovascular epidemiologic survey has been carried out in three different areas (Sakutocho, Sanyo-cho and Osafune-cho) of Okayama Prefecture since 1966. Cerebro-cardiovascular risk factors were investigated using data obtained in the first examination.The following results were obtained:1. Sixty-six cerebro-cardiovascular accidents (CCA) occurred in 1906 subjects over a ten year period (1966 to 1976); of these, 33 were cerebrovascular accidents (CVA) and 33 were cardiac accidents. The prevalence rate was the highest in Sakuto-cho and the lowest in Sanyocho. This reflected the degree of control of blood pressure.2. Cardiovascular accidents had a slightly higher prevalence rate in females than in males.3. CCA in males showed a positive correlation to increase in relative body weight. In females, there was no significant relationship between CCA and relative body weight.4. Compared to subjects with normal urinalysis, the prevalence rate of CCA was 1.7 in subjects with proteinuria and 3.2 in those with glucosuria.5. CCA occurred more frequently in both the systolic hypertension group and the group with combined systolic and diastolic hypertension.
We report here an autopsy case of sporadic adult‐onset Hallervorden‐Spatz syndrome, also known as neurodegeneration with brain iron accumulation type 1 (NBIA1), without hereditary burden. A 49‐year‐old woman died after a 27‐year disease course. At the age of 22, she suffered from akinesia, resting tremor, and rigidity. At the age of 28, she was admitted to our hospital because of worsening parkinsonism and dementia. Within several years, she developed akinetic mutism. At the age of 49, she died of bleeding from a tracheostomy. Autopsy revealed a severely atrophic brain weighing 460 g. Histologically, there were iron deposits in the globus pallidus and substantia nigra pars reticulata, and numerous axonal spheroids in the subthalamic nuclei. Neurofibrillary tangles were abundant in the hippocampus, cerebral neocortex, basal ganglia, and brain stem. Neuritic plaques and amyloid deposits were absent. Lewy bodies and Lewy neurites, which are immunolabeled by anti‐α‐synuclein, were absent. We also observed the presence of TDP‐43‐positive neuronal perinuclear cytoplasmic inclusions, with variable frequency in the dentate gyrus granular cells, frontal and temporal cortices, and basal ganglia. TDP‐43‐positive glial cytoplasmic inclusions were also found with variable frequency in the frontal and temporal lobes and basal ganglia. The present case was diagnosed with adult‐onset NBIA‐1 with typical histological findings in the basal ganglia and brainstem. However, in this case, tau and TDP‐43 pathology was exceedingly more abundant than α‐synuclein pathology. This case contributes to the increasing evidence for the heterogeneity of NBIA‐1.
Papers presented at this session include: temperature distributions in asphalt pavements (himeno,k, watanabe,t and maruyama,t); transient effects in low temperature induced failure and fracture initiation in a pavement structure (selvadurai,aps, phang,wa and au,mc); cold climate performance of Canadian airport pavements (haas,r, lee,h and meyer,f); applications of a method for evaluation of low temperature tensile properties of asphalt concrete (anderson,ko and leung,sc); evaluation of bearing capacity of asphalt pavement with low-temperature transverse cracking (kasahara,a and yoshida,h); laboratory investigations of low temperature cracking susceptibility of asphalt concrete (janoo,vc and chamberlain,ej); results of laboratory tests on amir compacted asphalt slabs (abd el halim,ao, mshana,g and sithole,v). For the covering abstract of the conference see IRRD 807037.
Vectorcardiograms were recorded with the Frank lead system during laparoscopy. Pneumoperitoneum produced the following significant vectorcardiographic changes: (1) The maximum spatial QRS vector increased in magnitude and shifted horizontally and slightly anteriorly. (2) The L/W ratio of the frontal QRS loop decreased. (3) The scalar data of each X, Y, Z lead of the QRS loop increased. In particular, the increases in R of all three leads and in S of lead Z were significant. These results suggest that the changes in the cardiac anatomic position due to lift of the diaphragma and a decrease of left ventricular end-diastolic volume might produce these vectorcardiographic changes during laparoscopy.
The mechanical properties of a rock or a soil are different in a narrow area. However, it is difficult to get their sample and to perform a various types of tests from the view points of time and economy. Thus, in this study, Equotip hardness test is focused. Because the test is easy to measure, it is possible to carry on the test at several points in a short time. Additionally, the cost performance of the test is excellent. In this article, the compression test for several artificial specimens is conducted, Equotip hardness test is also conducted before and after the compression test. Through the comparison between the measured data by the Equotip hardness test and the various properties, it turned out that the various properties can be presumed by Equotip hardness test.
