Marie Laure Delignette‐Muller

Laboratoire de Biométrie et Biologie Evolutive

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Sandrine Charles

Laboratoire de Biométrie et Biologie Evolutive

ÉB

Élise Billoir

Centre National de la Recherche Scientifique

Jean‐Pierre Flandrois

Laboratoire de Biométrie et Biologie Evolutive

Aurélie Siberchicot

Laboratoire de Biométrie et Biologie Evolutive

C. Vernozy‐Rozand

École Nationale Vétérinaire de Toulouse

Marie Cornu

Centre National de la Recherche Scientifique

Floriane Larras

Centre d'Etudes Prospectives et d'Informations Internationales

Florent Baty

Kantonsspital St. Gallen

Philippe Veber

Laboratoire de Biométrie et Biologie Evolutive

Régis Pouillot

Center for Food Safety and Applied Nutrition

Cooperative Institutions

Université Claude Bernard Lyon 1

101

Centre National de la Recherche Scientifique

VetAgro Sup

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Laboratoire de Biométrie et Biologie Evolutive

Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail

École Nationale Vétérinaire de Toulouse

Inserm

Institut National de la Recherche Agronomique

Stress Environnementaux et Biosurveillance des Milieux Aquatiques

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Development, feeding, and sex shape the relative quantity of the nutritional obligatory symbiont Wolbachia in bed bugs

Frontiers in Microbiology (2024)

Marius Poulain Elodie Rosinski Hélène Henri Séverine Balmand Marie Laure Delignette‐Muller

The common bed bug,

Bed bug

Cimex lectularius

10.3389/fmicb.2024.1386458

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Citations (2)

Approche de Modélisation Hiérarchique pour la Description de l'Effet de la Compétition Interspécifique sur la Tolérance Chimique d'Herbacées

HAL (Le Centre pour la Communication Scientifique Directe) (2019)

Vincent Baillard Marie Laure Delignette‐Muller Cécile Sulmon Anne‐Kristel Bittebiere Cendrine Mony

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Statistical cautions when estimating DEBtox parameters

Journal of Theoretical Biology (2008)

Élise Billoir Marie Laure Delignette‐Muller Alexandre R.R. Péry Olivier Geffard Sandrine Charles

Daphnia magna

Ecotoxicity

Data set

Experimental data

10.1016/j.jtbi.2008.05.006

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Citations (47)

Assessment of Ozone or Not-Treated Wastewater Ecotoxicity Using Mechanism-Based and Zebrafish Embryo Bioassays

Journal of Environmental Protection (2018)

Adriana Wigh Sélim Aı̈t-Aı̈ssa Nicolas Creusot Hugo Terrisse Marie Laure Delignette‐Muller

Toxicity of wastewater treatment plant (WWTP) effluents is usually assessed with standardized bioassays, as e.g. the Fish Embryo Toxicity test (FET), but assessment of sub-lethal toxic effects requires to develop more adapted tests. The present work aimed to add the recording of several sub-lethal endpoints in exposed zebrafish embryo-larval stages in order to increase the sensitivity of residual toxicity evaluation of WWTP effluents using a semi-quantitative method (iFET score). This approach was complemented with the genotoxicity assessment on the exposed embryos, a sub-acute hazard particularly relevant to evaluate a potential chronic toxicity risk of low and multi-contaminated environmental matrices. Additionally, endocrine activities of effluents were quantified using human reporter cell lines. This test battery was applied to the assessment of the residual toxicity of five biological treatment effluents, further treated or not using various ozonation treatments intended to improve pharmaceutical compounds removal. Acute toxicity towards zebrafish embryos was very low. However, iFET score approach proposed was able to reveal residual toxicity through the presence of developmental abnormalities in all samples tested. Additionally, a low residual genotoxicity was measured in embryos exposed to two of the WWTP effluents when all excepted one exhibited a residual endocrine activity potential in the ng/L range providing complementary information on the occurrence of endocrine active chemicals and their reduction by different processes. To sum up, such a simplified and ecologically relevant test battery was found sensitive enough to characterize and differentiate various residual effluent’s ecotoxicity at contaminant levels of environmental concern.

Ecotoxicity

Developmental toxicity

10.4236/jep.2018.94022

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Citations (7)

Meta-transcriptomics reveals stress adaptation processes in microbial communities differing in exposure history

Floriane Larras Élise Billoir S. H. Lips S Schreiber Philippe Veber

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Dose Response for Omics [R package DRomics version 2.2-0]

Marie Laure Delignette‐Muller Élise Billoir Aurélie Siberchicot