Jen‐Fu Huang

Chang Gung Memorial Hospital

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Chien‐Hung Liao

Chang Gung University

Chih‐Yuan Fu

Linkou Chang Gung Memorial Hospital

Chi‐Tung Cheng

Linkou Chang Gung Memorial Hospital

Chih-Po Hsu

Linkou Chang Gung Memorial Hospital

Chi‐Hsun Hsieh

Linkou Chang Gung Memorial Hospital

Ling‐Wei Kuo

Linkou Chang Gung Memorial Hospital

Chun‐Hsiang Ou Yang

Chang Gung University

Chien-An Liao

Chang Gung Memorial Hospital

Chia‐Cheng Wang

Chang Gung University

Szu-An Chen

Chang Gung University

Cooperative Institutions

Virginia Department of Environmental Quality

138

Accreditation Council for Graduate Medical Education

130

Pediatric Oncology Group

119

Chang Gung University

Chang Gung Memorial Hospital

Linkou Chang Gung Memorial Hospital

Society of Thoracic Surgeons

Memorial Hospital of South Bend

Weatherford College

New York Proton Center

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The Impact of Selenium Supplementation on Trauma Patients—Systematic Review and Meta-Analysis

Nutrients (2022)

Jen‐Fu Huang Chih-Po Hsu Chun-Hsiang Ouyang Chi‐Tung Cheng Chia‐Cheng Wang

This study aimed to assess current evidence regarding the effect of selenium (Se) supplementation on the prognosis in patients sustaining trauma. MEDLINE, Embase, and Web of Science databases were searched with the following terms: "trace element", "selenium", "copper", "zinc", "injury", and "trauma". Seven studies were included in the meta-analysis. The pooled results showed that Se supplementation was associated with a lower mortality rate (OR 0.733, 95% CI: 0.586, 0.918, p = 0.007; heterogeneity, I2 = 0%). Regarding the incidence of infectious complications, there was no statistically significant benefit after analyzing the four studies (OR 0.942, 95% CI: 0.695, 1.277, p = 0.702; heterogeneity, I2 = 14.343%). The patients with Se supplementation had a reduced ICU length of stay (standard difference in means (SMD): -0.324, 95% CI: -0.382, -0.265, p < 0.001; heterogeneity, I2 = 0%) and lesser hospital length of stay (SMD: -0.243, 95% CI: -0.474, -0.012, p < 0.001; heterogeneity, I2 = 45.496%). Se supplementation after trauma confers positive effects in decreasing the mortality and length of ICU and hospital stay.

Web of science

Subgroup analysis

10.3390/nu14020342

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Citations (12)

Contemporary management and prognosis of great vessels trauma

Injury (2019)

Szu-An Chen Jen‐Fu Huang Yu‐San Tee Shao‐Wei Chen Shang‐Yu Wang

10.1016/j.injury.2019.03.054

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Citations (3)

Impact of Deferred Surgical Intervention on the Outcome of External Laryngeal Trauma

The Annals of Thoracic Surgery (2014)

Chien‐Hung Liao Jen‐Fu Huang Shao-Wei Chen Chih‐Yuan Fu Li‐Ang Lee

Decompensation

Trauma Center

Major trauma

10.1016/j.athoracsur.2014.04.079

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Citations (3)

Feasibility of non-operative management for patients sustained blunt splenic traumas with concomitant aortic injuries

European Journal of Trauma and Emergency Surgery (2023)

Jen‐Fu Huang Chia‐Cheng Wang Shu-Yueh Shen Chih‐Yuan Fu Chih-Po Hsu

Concomitant

Sports medicine

10.1007/s00068-023-02403-9

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Citations (1)

Timely surgical fixation confers beneficial outcomes in patients’ concomitant flail chest with mild-to-moderate traumatic brain injury: a trauma quality improvement project analysis – a cohort study

International Journal of Surgery (2023)

Chien-An Liao Ling‐Wei Kuo Jen‐Fu Huang Chih‐Yuan Fu Szu-An Chen

Traumatic flail chest results in respiratory distress and prolonged hospital stay. Timely surgical fixation of the flail chest reduces respiratory complications, decreases ventilator dependence, and shortens hospital stays. Concomitant head injury is not unusual in these patients and can postpone surgical timing due to the need to monitor the status of intracranial injuries. Reducing pulmonary sequelae also assists in the recovery from traumatic brain injury and improves outcomes. No previous evidence supports that early rib fixation can improve the outcome of patients with concomitant flail chest and traumatic brain injury.Can early rib fixation improve the outcome of patients with concomitant flail chest and traumatic brain injury?Adult patients with blunt injuries from the Trauma Quality Improvement Project between 2017 and 2019 were eligible for inclusion. Patients were divided into two treatment groups: operative and nonoperative. Inverse probability treatment weighting was used to identify the predictors of mortality and adverse hospital events.Patients in the operative group had a higher intubation rate [odds ratio (OR), 2.336; 95% CI, 1.644-3.318; p <0.001), a longer length of stay (coefficient β , 4.664; SE, 0.789; p <0.001), longer ventilator days (coefficient β , 2.020; SE, 0.528; p <0.001), and lower mortality rate (OR], 0.247; 95% CI, 0.135-0.454; p <0.001).Timely rib fixation can improve the mortality rate of patients with flail chest and a concomitant mild-to-moderate head injury.

Flail Chest

Concomitant

Abbreviated Injury Scale

10.1097/js9.0000000000000271

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Citations (2)

Is massive hemothorax still an absolute indication for operation in blunt trauma?

Injury (2020)

Jen‐Fu Huang Chih-Po Hsu Chih‐Yuan Fu Chun‐Hsiang Ou Yang Chi‐Tung Cheng

Hemothorax

Chest tube

Chest injury

Therapeutic effect

10.1016/j.injury.2020.12.016

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Citations (3)

Deep Learning for Automated Detection and Localization of Traumatic Abdominal Solid Organ Injuries on CT Scans

Deleted Journal (2024)

Chi‐Tung Cheng Hou-Hsien Lin Chih-Po Hsu Huan‐Wu Chen Jen‐Fu Huang

Abstract Computed tomography (CT) is the most commonly used diagnostic modality for blunt abdominal trauma (BAT), significantly influencing management approaches. Deep learning models (DLMs) have shown great promise in enhancing various aspects of clinical practice. There is limited literature available on the use of DLMs specifically for trauma image evaluation. In this study, we developed a DLM aimed at detecting solid organ injuries to assist medical professionals in rapidly identifying life-threatening injuries. The study enrolled patients from a single trauma center who received abdominal CT scans between 2008 and 2017. Patients with spleen, liver, or kidney injury were categorized as the solid organ injury group, while others were considered negative cases. Only images acquired from the trauma center were enrolled. A subset of images acquired in the last year was designated as the test set, and the remaining images were utilized to train and validate the detection models. The performance of each model was assessed using metrics such as the area under the receiver operating characteristic curve (AUC), accuracy, sensitivity, specificity, positive predictive value, and negative predictive value based on the best Youden index operating point. The study developed the models using 1302 (87%) scans for training and tested them on 194 (13%) scans. The spleen injury model demonstrated an accuracy of 0.938 and a specificity of 0.952. The accuracy and specificity of the liver injury model were reported as 0.820 and 0.847, respectively. The kidney injury model showed an accuracy of 0.959 and a specificity of 0.989. We developed a DLM that can automate the detection of solid organ injuries by abdominal CT scans with acceptable diagnostic accuracy. It cannot replace the role of clinicians, but we can expect it to be a potential tool to accelerate the process of therapeutic decisions for trauma care.

Youden's J statistic

Trauma Center

10.1007/s10278-024-01038-5

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Citations (10)

Management of acute cholecystitis in patients older than the expected life expectancy: Is the Tokyo Guidelines 2018 still practical?

Research Square (Research Square) (2024)

Yau-Ren Chang Yu‐Tung Wu Szu-An Chen Chih‐Yuan Fu Chih-Po Hsu

Abstract Background As the global population ages, the incidence of acute cholecystitis is increasing. Tokyo Guidelines 2018 are established as the standard for managing this condition. However, the applicability in elderly patients, who often have comorbidities and higher surgical risks, is uncertain. This study assesses the feasibility of using the guidelines to manage acute cholecystitis in patients aged 85 and older. Methods We conducted a retrospective analysis on patients aged ≥ 85 diagnosed with acute cholecystitis between 2011 and 2021. Patient demographics, disease severity, comorbidities, and treatment outcomes were examined. Patients were categorized into three groups based on severity and adherence to recommendations. Results Among 166 elderly patients with acute cholecystitis, guideline compliance varied by severity. Adherence to the guidelines resulted in better outcomes, including shorter hospital stays and fewer complications, for mild (group I) and moderate (group II) cases. Severe cases (group III) had similar outcomes regardless of guideline adherence. Conclusions This study suggests that the Tokyo Guidelines 2018 is applicable to elderly patients aged 85 and older with acute cholecystitis. Better outcomes were observed when patients followed the guidelines, particularly in mild and moderate cases. Tailoring treatment to individual needs is paramount for optimizing outcomes in severe cases within this age group.

10.21203/rs.3.rs-3918012/v1

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How much could a low COVID-19 pandemic change the injury trends? A single-institute, retrospective cohort study

BMJ Open (2021)

Ling‐Wei Kuo Chih‐Yuan Fu Chien-An Liao Chien‐Hung Liao Yu‐Tung Wu

Objectives COVID-19 has changed the epidemiology of trauma. However, Taiwan is a country with a low COVID-19 threat, and people’s daily lives have remained mostly unchanged during this period. The purpose of this study is to investigate whether the trend of trauma incidence and the service of trauma care is affected by the relatively minor COVID-19 pandemic in Taiwan. Design A single-institute, retrograde cohort study. Setting An observational study based on the trauma registry of Chang Gung Memorial Hospital (CGMH). Participants Trauma patients presented to the emergency department of CGMH in the period of 1 January to 30 June 2020 (week 1 to week 26) were designated as the COVID-19 group, with 1980 patients in total. Patients of the same period in 2015–2019 were designated as the pre-COVID-19 group, with 10 334 patients overall. Primary and secondary outcome measures The primary outcome is the incidence of trauma admission. Differences in trauma mechanism, severity, location and outcome were also compared in both groups. Results A decrease in trauma incidence during March and April 2020 was noticed. Significant change (p<0.001) in trauma mechanisms was discovered, with decreased burn (5.8% vs 3.6%) and assault (4.8% vs 1.2%), and increased transport accidents (43.2% vs 47.2%) and suicide (0.2% vs 1.0%) in the COVID-19 cohort. A shift in injury locations was also found with a 5% decrement of workplace injuries (19.8% vs 14.8%, p<0.001). Conclusion The limited COVID-19 outbreak in Taiwan has led to a decreased incidence of trauma patients, and the reduction is mostly attributed to the decline in workplace injuries.

Trauma Center

Pandemic

Major trauma

10.1136/bmjopen-2020-046405

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Citations (13)

Contents

The Annals of Thoracic Surgery (2014)

Lawrence T. Goodnough Jerrold H. Levy Susan D. Moffatt‐Bruce Chadrick E. Denlinger Robert M. Sade

10.1016/s0003-4975(14)01351-4

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Citations (0)