Summary. Having demonstrated in an earlier work that an artificial colloidal solution causes a systematic deviation in the THUNBERG Ci‐curve, the author poses the question: is the influence of the colloid content determined by a law, and does such a law concern also the Ci‐estimation in blood serum? Solutions of alb. ovi pulv. gummi arab. and gall of swine to which was added 10 γ/ml of Ci caused a systematic deviation of the Ci‐curve. The systematic deviation increased if the concentration of a given colloidal solution was increased. Different colloidal solutions in the same concentration caused systematic deviations of unequal degree. The figure for the expression the level line of the X‐curve/the level line of the standard curve called the level quotient, determines which tubes ought to be considered when estimating the Ci‐content of the X‐solution. By a higher figure of the level quotient the point for the exact value is regularly displaced upwards on the curve. Simultaneously the for the estimation of the Ci‐value best combination of several consecutive tubes is displaced upwards on the curve. The systematic deviation of the Ci‐curve is due to an acceleration of the reaction process in the upper part of the curve and a simultaneous retardation of the process in its lower part. A change in the colloidal properties of a given colloidal solution affects the degree of the systematic deviation. Parallel estimations of Ci in blood serum according to THUNBERG and according to PSV show that the same laws rule the systematic deviation in artificial colloidal solutions and in blood serum. This shows that the systematic deviation of the serum curve is due to the serum colloids. Parallel Ci‐estimations with the THUNBERG and PSV methods on venous blood of man gave almost identical results.

Value (mathematics)

Absolute deviation

Line (geometry)

10.1111/j.1748-1716.1945.tb00290.x

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