Supplementary Figure S21 showing that removal of mutant TRP53 does not impact the growth and survival of Eu-Myc mouse lymphoma cells in vitro and in vivo

Gain of function

Loss function

10.1158/2159-8290.25184435.v1

Cite

Citations (0)

Supplementary Data Figure S28 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells

Zilu Wang Matteo Burigotto Sabrina Ghetti François Vaillant Tao Tan

Supplementary Figure S28 showing that removal of mutant TP53 has no impact on the response of tumors derived from human colon cancer derived organoids to 5-FU in vivo

Gain of function

Loss function

10.1158/2159-8290.25184411

Cite

Citations (0)

Supplementary Data Table S8 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells

Zilu Wang Matteo Burigotto Sabrina Ghetti François Vaillant Tao Tan

Supplementary Table S8 showing the impact of removal of mutant KRAS in human cancer cell lines in vitro by CRISPR/Cas9 by mining the DepMap database

Gain of function

Table (database)

10.1158/2159-8290.25184363.v1

Cite

Citations (0)

Supplementary Data Figure S3 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells

Zilu Wang Matteo Burigotto Sabrina Ghetti François Vaillant Tao Tan

Supplementary Figure S3 showing that removal of mutant TP53 does not impair the ability of diverse human cancer cell lines to adapt to conditions of stress

Gain of function

Loss function

10.1158/2159-8290.25192850.v1

Cite

Citations (0)

Supplementary Data Figure S15 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells

Zilu Wang Matteo Burigotto Sabrina Ghetti François Vaillant Tao Tan

Supplementary Figure S15 showing that removal of mutant TP53 does not impair in vivo tumor growth of certain human cancer cell lines

Gain of function

Loss function

10.1158/2159-8290.25192895

Cite

Citations (0)

Supplementary Data Figure S11 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells

Zilu Wang Matteo Burigotto Sabrina Ghetti François Vaillant Tao Tan

Supplementary Figure S11 showing that removal of mutant TP53 does not cause a competitive growth disadvantage in diverse human cancer cell lines in culture

Gain of function

10.1158/2159-8290.25192907

Cite

Citations (0)

Supplementary Data Figure S13 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells

Zilu Wang Matteo Burigotto Sabrina Ghetti François Vaillant Tao Tan

Supplementary Figure S13 showing that mutant TP53 deficient human cancer cell lines retain the machinery to respond to the activation of wt TP53

Gain of function

10.1158/2159-8290.25192901

Cite

Citations (0)