Aims: Transcatheter based aortic valve replacement (AVR) is a promising procedure to reduce operative risk especially in old patients with significant comorbidities. We report the initial series of transapical and transfemoral-AVR including 1 year follow up.
Devices for hydrodynamic simulation are required in a variety of studies such as device evaluation, cardiovascular modeling and for student training. Most studies today use different, incompatible circuits, which must be redesigned for every new application. To obtain a universal apparatus, a unitized system with standard connectors was developed. Three types of connectors were selected: 1″ flange connectors, ½″ tubing connectors and Luer-connectors with a 2 mm lumen. The complete system consists of reservoirs, throttles, valve holders, adapters for Doppler ultrasound probes, and converters to link these basic diameters. The apparatus can be driven by membrane, centrifugal and geared pumps. The system has successfully been used in echocardiographic studies of stenosis and valvular insufficiency, for pulse propagation in vascular grafts, and to test the hydraulic performance of cardiac assist devices. Flow rates between 0.1 and 30 l/min and pressure gradients up to 250 mmHg were achieved. In practical use, the system can be adapted to suit various investigations, with minimal expense. Standardization of the parts and connectors results in simple documentation and good reproducibility.
Letters and Corrections1 October 1983Clonidine and HyperhidrosisFRIEDRICH CONRAD, M.D., HOLGER BAUMGARTNER, M.D., CHRISTIAN WIEDERMANN, M.D., GEORG KLEIN, M.D.FRIEDRICH CONRAD, M.D., HOLGER BAUMGARTNER, M.D., CHRISTIAN WIEDERMANN, M.D., GEORG KLEIN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-99-4-570_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Because emotional sweating is under sympathetic control (1), clonidine, known to inhibit sympathetic tone (2), could be useful in the treatment of excessive emotional sweating (hyperhidrosis), a disorder that is still a therapeutic problem (1). Several reports imply a possible inhibition of sweating by clonidine in various conditions, including diabetic gustatory sweating (3, 4). In the summer of 1979, we tested clonidine in six hyperhidrotic patients (three palmar, two plantar, and one axillar) who had considered surgical sympathectomy. Informed consent was obtained before the study.Intravenous clonidine, 1.8 mg/kg body weight, was tested twice (single blind) in...References1. QUINTON P. Sweating and its disorders. Ann Rev Med. 1983;34:429-52. CrossrefMedlineGoogle Scholar2. LOWENSTEIN J. Clonidine. Ann Intern Med. 1980;92:74-7. LinkGoogle Scholar3. JANKASTANDLMEHNERT HEH. Clonidine effect on diabetic gustatory sweating. Ann Intern Med. 1979;91:130. LinkGoogle Scholar4. WALLAND A. Inhibition of sudomotor transmission in the cat's stellate ganglion by activation of somadendritic α2-adrenoceptors. In: BOCK KD, ed. Catapresan (Clonidine). Aulendorf: Editio Cantor; 1983:92-110. (Arzneimittel-Forschung/Drug Research Vol. 28). Google Scholar5. SHIHLIN CM. Effects of cholinomimetic drugs on sudomotor, metabolic, respiratory, vasomotor, and temperature response in palmar hyperhidrosis. J Neurosurg. 1980;53:684-9. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTherapie der HyperhidrosisHyperhidrose und SchweißdrüsenerkrankungenHyperhidrosis und SchweißdrüsenerkrankungenInhibiting noradrenergic overactivity by inhibition of thromboxane and concomitant activation of opiate receptors via dietary meansCorrection: Incorrect Dosage 1 October 1983Volume 99, Issue 4Page: 570-570KeywordsBody weightEmotionsSympathectomy Issue Published: 1 October 1983 PDF downloadLoading ...
