E Stroe

Universitäts Frauenklinik

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Document Type

Co-Authors

D Drafta

Albert Einstein College of Medicine

A Cristoveanu

Institute of Endocrinology

A Tache

Centre Hospitalier Universitaire de Besançon

I Klepsch

Institute for Diagnosis and Animal Health

Serban Am

M Oprescu

Spitalul Clinic Judetean de Urgentã Craiova

C Ciocîrdia

Institutul Național de Endocrinologie C.I. Parhon

A. E. Schindler

Krasnoyarsk State Medical University

M Bunea

Clinical Emergency Hospital Bucharest

Elena Neacşu

Horia Hulubei National Institute for R and D in Physics and Nuclear Engineering

Cooperative Institutions

Institute of Endocrinology

Institutul Național de Endocrinologie C.I. Parhon

Clinical Emergency Hospital Bucharest

Universitäts Frauenklinik

Institutul Clinic Fundeni

Carol Davila University of Medicine and Pharmacy

Institutul Oncologic Bucuresti

Institut für Medizinische Informatik, Biometrie und Epidemiologie

Essen University Hospital

Klinik für Frauenheilkunde

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Research Field

Hepatic and extrahepatic steroid metabolism in extracorporeal circulation with and without hypothermia in dogs.

PubMed (1969)

Milcu Sm E Păuşescu D Drafta E Stroe C Ciocîrdia

Extracorporeal circulation

Extracorporeal

Liver circulation

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Citations (1)

Adrenal function in early and metastatic breast cancer: dexamethasone suppression of plasma cortisol.

PubMed (1981)

Drafta Ds E Stroe Schindler Ee T Teodosiu L Gozariu

Plasma cortisol, 17-hydroxyprogesterone (17-OH-P), progesterone, FSH, LH and prolactin were determined by RIA, in 14 cancer patients without metastases aged between 40 and 74 years (6 cases of breast cancer: T123, N01, M0 and 8 with other forms of cancer). The cancer patients were investigated: (A) under basal conditions, (B) after three days' adrenal suppression by dexamethasone, 3 mg/day and (C) immediately after local radiation therapy (4500 rads). The basal mean hormonal values in these patients showed increased cortisol, decrease 17-OH-P and normal values of progesterone, FSH, LH and prolactin. Plasma cortisol was significantly reduced by adrenal suppression with a percentage reduction of 19.44 without differences between breast cancer patients and patients with other forms of cancer; adrenal suppression induced an increase of 17-OH-P only in male cancer patients. The only significant hormonal changes after local radiation therapy were increased plasma 17-OH-P values in both female and male cancer patients. A second group investigated in the present study consisted of 11 patients (6 castrated and 5 postmenopausal women) with metastatic breast cancer and presented increased plasma cortisol values, decreased 17-OH-P values, and a great scatter in the estrone values, some of them being very high.

Basal (medicine)

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Citations (7)

Urinary, plasma and adrenal tissue steroids in a male patient with Cushing's syndrome due to adrenal carcinoma.

PubMed (1978)

D Drafta Federico Franchi M. Luisi E Stroe

The dynamics of urinary and plasma steroids (CPB and RIA) were simultaneously studied in a 36-yr-man with Cushing's syndrome due to adrenal carcinoma. The markedly increased basal excretion of 5-pregnenetriol, PG, PGT, DHA, THS and corticosteroids with nonsignificant changes during the endocrine tests decreased to normal levels after tumour removal. The basal low level of plasma testosterone, with nonsignificant changes during the endocrine tests, rose progressively after surgery. The steroid content of adrenal carcinoma tissue determined by CPB and RIA after LH-20-Sephadex CC separation revealed important proportion of unconjugated 17-OH-P.

Basal (medicine)

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Citations (2)

[Macromastia of puberty and mammary hyperreceptivity].

PubMed (1967)

C Wolfshaut E Nedelniuc A Cristoveanu I Klepsch E Stroe

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Citations (0)

Clinical features of psychiatric disorders in Parkinson’s disease

Psihiatru ro (2024)

E Stroe Raluca Pretorian

Parkinson's disease (PD) is essentially characterized by the motor symptoms in the form of resting tremor, rigidity and bradykinesia. However, over the years it has been recognized that motor symptoms are just the "tip of the iceberg" of the clinical manifestations of PD. Besides motor symptoms, PD is characterized by many non-motor symptoms, which include cognitive decline, psychiatric disturbances (depression, psychosis and impulse control disorders), sleep difficulties, autonomic failures (gastrointestinal, cardiovascular, urinary, thermoregulation), and pain syndrome. This review evaluates the various aspects of psychiatric disorders, including cognitive decline and sleep disturbances, in patients with PD. The prevalence rate of various psychiatric disorders is high in patients with Parkinson's disease. Evidence also suggests that the presence of psychiatric morbidity is associated with poorer outcome. To conclude, this review suggests that psychiatric morbidity is highly prevalent in patients with Parkinson's disease. Hence, a multidisciplinary approach must be followed to improve the overall outcome of this disease. Further studies are required to evaluate the efficacy of various other measures for the management of psychiatric morbidity in patients with Parkinson's disease.

10.26416/psih.77.2.2024.9738

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HORMONE ELIMINATION IN ASYMPTOMATIC CLIMACTERIC

Serban Am E Stroe I Klepsch A Cristoveanu

Climacteric

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388. Effect of hormonal therapy on plasma progesterone and 17β-estradiol levels in cows suffering from cystic ovarian degeneration

Journal of Steroid Biochemistry (1978)

V.P. Dixit D Drafta E Stroe S. K. Khar F. Seiciu