Gurdeep Singh Dhooria

Dayanand Medical College & Hospital

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Deepak Bhat

Dayanand Medical College & Hospital

Puneet A. Pooni

Dayanand Medical College & Hospital

Shruti Kakkar

Dayanand Medical College & Hospital

Siddharth Bhargava

Dayanand Medical College & Hospital

Harmesh Singh Bains

Punjab Institute of Medical Sciences

Karambir Gill

Dayanand Medical College & Hospital

Kamal Arora

Dayanand Medical College & Hospital

Nancy Goel

Dayanand Medical College & Hospital

Harmeet Pal Singh Dhooria

Dayanand Medical College & Hospital

Kamaldeep Arora

Dayanand Medical College & Hospital

Cooperative Institutions

Dayanand Medical College & Hospital

Post Graduate Institute of Medical Education and Research

Public Works Department Buildings and Roads

Institute of Medical Sciences

Government Medical College

All India Institute of Medical Sciences

Cleveland Clinic

Government Medical College and Hospital

Max Super Speciality Hospital

Medanta The Medicity

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CLINICAL PROFILE AND OUTCOME IN CHILDREN OF DENGUE HEMORRHAGIC FEVER IN NORTH INDIA

Iranian Journal of Pediatrics (2008)

Gurdeep Singh Dhooria Deepak Bhat Harmesh Singh Bains

Objective: The number of dengue fever (DF)/dengue hemorrhagic fever (DHF) cases reported in India has risen in recent years. This study was undertaken to evaluate clinical profile and outcome of children admitted with DHF/dengue shock syndrome (DSS), in the 2006 DHF epidemic in Ludhiana, Punjab. Methods: Eighty one children with dengue hemorrhagic fever were hospitalized in the Pediatric Department of Dayanand Medical College and Hospital, Ludhiana, India. All patients were diagnosed, managed and monitored according to a standard protocol. Findings: Children between 10-15 years were most commonly afflicted (59%). Infants were the least affected sub-group (3.7%). Ninety two percent of all children were of DHF and 8% cases presented in DSS. The common symptoms seen were fever (91%), vomiting (41%), poor intake (21%), abdominal pain (16%) and significant bleeding (15%). Hepatomegaly was present in 60% of cases. 85% of cases had petechiae alone, 15% had evidence of significant bleeding manifestation. Gastrointestinal bleeding was the commonest observed bleeding. The complications seen were liver dysfunction (14.8%), coagulopathy (3.7%), renal dysfunction (3.7%), and acute respiratory distress syndrome (2.4%) and disseminated intravascular coagulation (1.2%). Mortality in the study was 3.7%. Refractory shock and coagulopathy were seen in all cases with poor outcome. Conclusion: Increased awareness, better transport facilities and case management according to the WHO guidelines, is needed to further reduce mortality of DHF/DSS cases.

Dengue hemorrhagic fever

Gastrointestinal bleeding

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Abstract P-179: CLINICAL PROFILE AND OUTCOME OF CRITICALLY SICK CHILDREN OF TROPICAL FEVER ADMITTED IN PICU OF A TERTIARY CARE HOSPITAL

Pediatric Critical Care Medicine (2018)

Deepak Bhat Gurdeep Singh Dhooria Shruti Kakkar Saurabh Verma

Aims & Objectives: To study the clinical profile and out come of sick children of tropical fever Methods This was a prospective observational study conducted over the post monsoon months of august to November 2017 at the PICU of Dayanand Medical College and Hospital,which is a teaching tertiary care hospital in the northern part of India. Clinical features, laboratory parameters and final outcome were studied and analsed Results Out of a total of 201 patients admitted with diagnosis of tropical fever,45 (22.3%) got admitted in the PICU..Fever,pain abdomen and vomiting were the most common presenting symptoms.Bleeding at presentation was seen in 28.8% children,shock in 73.3%,ascites in 46.6%,respiratory complications in 42.2% and anemia in 66.6%.The underlying etiology was dengue fever(33.3%),scrub typhus(6.6%),malaria(4.4%), leptospirosis(4.4%) and swine flu(2%).Out of 45 children,10(22.2%) died,33 (73.3%) were transferred to ward and 2 (4.4%) left against medical advice. Conclusions During the post monsoon months there is a surge in the patients of tropical fever.Some of these patients are sick and if managed in PICU with standard protocols,many of them can be saved.

myalgia

Etiology

10.1097/01.pcc.0000537636.54400.a6

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Citations (1)

Oral cyclophosphamide therapy in 100 children with steroid-sensitive nephrotic syndrome: experience from a developing country

Pediatric Nephrology (2021)

Jasjeet Sandhu Deepak Bhat Gurdeep Singh Dhooria Puneet A. Pooni Siddharth Bhargava

Nephrology

10.1007/s00467-021-05052-5

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Utilization of the renal angina index in PICU of a developing country for prediction of subsequent severe acute kidney injury

Pediatric Nephrology (2018)

Raina Kaur Gurdeep Singh Dhooria Puneet A. Pooni Deepak Bhat Siddharth Bhargava

Nephrology

Unstable angina

10.1007/s00467-018-4001-8

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Citations (19)

Review of: "Acute Kidney Injury in Pediatric Patients with COVID-19; Clinical Features and Outcome"

Gurdeep Singh Dhooria

Striking incidence of AKI in covid patients, out of 187 patients included, 72 patients had AKI.

2019-20 coronavirus outbreak

10.32388/rovqe3

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Head drop and flaccid weakness in infantile nephrotic syndrome

Indian Journal of Nephrology (2018)

Gurdeep Singh Dhooria

Dropped head syndrome (DHS) is a relatively rare condition, with a broad differential diagnosis. We report here a case of infantile nephrotic syndrome with DHS caused by severe hypokalemia. Electrocardiogram showed flat T- and U-waves. Multiple factors including recurrent diarrhea, prolonged diuretic and corticosteroid use, hypomagnesemia, poor intake, and malnutrition caused hypokalemia in the case. Head drop and flaccid weakness resolved completely after potassium and magnesium supplementation. Potassium levels should be monitored and corrected promptly in these settings.

Muscle weakness

10.4103/ijn.ijn_198_16

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ACUTE HEMORRHAGIC LEUKOENCEPHALITIS SECONDARY TO SEVERE DIABETIC KETOACIDOSIS

Deepak Bhat Gurdeep Singh Dhooria Shruti Kakkar

Acute hemorrhagic leukoencephalitis is a fulminant demyelinating disease and commonly considered as a rare and severe variant of acute disseminated encephalomyelitis.It is also known as Weston-Hurst syndrome and is an excessive immunological response of unknown etiology.So far, an association with diabetic ketoacidosis has not been reported. ACUTE HEMORRHAGIC LEUKOENCEPHALITISSECONDARY TO SEVERE DIABETIC KETOACIDOSIS CASE REPORT An 8 year old female child presented to our emergency department with complaints of cough for 4 days, difficulty in breathing and altered sensorium for 2 days.Child was earlier admitted in our hospital and diagnosed as a case of IDDM and discharged on subcutaneous insulin.examination child was in altered sensorium.Vitals included a Heart rate of 180/mt with sinus rhythm, weak peripheral pulses ,Blood Pressure of 88/50 mmHg, capillary refill time of 3 seconds, respiratory rate of 50/mt with subcostal retractions.Glasgow coma scale was E3M5V3.Blood sugar of 300mg/dl and blood ketone level of 6.9.Renal functions showed an creatinine 1.38, BUN of 144.Child was managed as a case of severe DKA with pulmonary infection.Child got intubate on 2 and started ventilation.Patient was started on peritoneal dialysis on day 3. Patient was extubated on day 8. On day 12 child had seizures and had to be reintubated and again put on ventilator support.MRI brain done showed hemorrhagic leukoencephalitis (Image 1).Child was started on pulse dexamethasone for 3 days, got extubated on day 14.

Diabetic ketoacidosis

10.26226/morressier.5b5f433cb56e9b005965b850

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ABSTRACT 595

Pediatric Critical Care Medicine (2014)

Deepak Bhat Gurdeep Singh Dhooria

Background and aims: neonatal septicemia is a common cause of mortality in infants.This case report highlights a rare species of pseudomonas causing sepsis in a neonate. Aims: to report a case of neonatal septicemia caused by a rare species of pseudomonas. Methods: case report. Results: A 1 month old neonate,was admitted in our emergency with complaints of erythematous rash over body on the day of admission.On examination multiple bullous eruptions were seen in bilateral; infraaxillary areas with few showing peeling of overlying skin also.To begin with there was only single lesion on left side(pea sized) but subsequently multiple lesions appeared with rupturing of some of them.There was no apparent history of trauma,insect bite,drug intake,fever,feeding difficulties etc.Vitals included RR-60/mt,HR-159/mt,CFT-2secs,Temp-98.1 deg F,alert baby.In birth history,child was a term SGA baby delivered by LSCS.Rest of the systemic examination was normal.Initial impression of bullous impetigo was kept.Other investigations done revealed a CRP of 22.6 mg/dl(normal range 0–6 mg/dl).Blood culture grew pseudomonas stutzeri.Child was given IV Ceftazedime as per sensitivity. Patient was discharged in a stable condition. Conclusions: pseudomonas stutzeri has rarely been reported as a cause of neonatal septicemia.

Pseudomonas stutzeri

Impetigo

Neonatal Sepsis

10.1097/01.pcc.0000449321.75585.a9

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Pulmonary functions in normal school children in the age group of 6-15 years in north India.

PubMed (2010)

Sandeep Budhiraja Daljit Singh Puneet A. Pooni Gurdeep Singh Dhooria

Lung function tests have become an integral part of assessment of pulmonary disease. As few studies on pulmonary function tests have been carried out in young children in India, the study was carried out in normal urban and rural school children in Ludhiana district of North India to determine pulmonary functions in the age group 6-15 years and to find its correlation with regards to age, sex, height and weight.The study group included 600 normal children between 6-15 years age from different urban and rural schools in the region. A preformed questionnaire was interviewed and detailed general physical and systemic examination was done. Pulmonary function tests were measured by using Micromedical Gold standard fully computerized portable auto spirometer (Superspiro Cat No. SU 6000).The present study shows, all the three independent variables (age, weight and height) have linear positive correlation with lung function parameters, both for boys and girls. Lung function values in boys were significantly higher as compared to that of girls. Urban children had higher lung function parameters than rural children except IRV, FEF(25%). Among all anthropometric parameters, height was the most independent variable with maximum coefficient of correlation.Equations derived from the present study for estimation of the expected values of lung function will help to interpret the observed lung function values in children of North India.

Spirometer

Gold standard (test)

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Multidimensional impact on families of children with steroid‐sensitive nephrotic syndrome

Journal of Paediatrics and Child Health (2017)

Gurdeep Singh Dhooria Harmeet Singh Deepak Bhat Harmesh Singh Bains Ravinder Kumar Soni

Aim Children with nephrotic syndrome ( NS ) have prolonged disease course with relapses requiring frequent visits and prolonged steroid therapy with their long‐term concerns. All these factors affect the child and their families in many domains of functioning. The objective of this study was to assess multidimensional impact on families of children with nephrotic syndrome using ( PedsQL ) Family Impact Module ( FIM ). Methods This cross‐sectional study was conducted in a paediatric nephrology clinic of a tertiary care hospital. Fifty cases of steroid‐sensitive nephrotic syndrome between age group of 2–18 years were included, and equal age–sex matched healthy children were taken as controls. Baseline demographic factors including age, gender and education status, modified Kuppuswamy's socio‐economic status were collected and clinical variables of NS cases were recorded. FIM is a parent‐reported instrument that measures the impact of paediatric chronic health conditions on care giver's HRQOL and their family function. Mean FIM scores were compared among the cases and controls, and different predictive factors affecting family impact (FI) were analysed. Results The FI total score showed significantly lower scores in cases (mean score: 60.76 ± 15.66) as compared to controls (mean 100). Among the individual groups, lowest scores were found in two domains, namely ‘worry’ and ‘emotional function’ with mean scores of 46.20 ± 20.66 and 46.80 ± 24.61, respectively, although other domains were also significantly affected. Conclusion FI score should be evaluated in all cases of NS as parenting such children may significantly affect all domains of family functioning.

Affect

Worry

Cross-sectional study

10.1111/jpc.13445

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Citations (10)