Zhijian Qain

University of Chicago

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Chongxu Zhang

University of Chicago

Theodore Christoforidis

National and Kapodistrian University of Athens

James Lee

Twin Cities Orthopedics

Tzu‐Pin Shentu

University of Chicago

Evgeny Berdyshev

National Jewish Health

Carlos Ng

University of Illinois Chicago

Ibra S. Fancher

University of Delaware

Yue Sheng

Second Xiangya Hospital of Central South University

David Eddington

University of Illinois Chicago

Pappasani V. Subbaiah

University of Chicago

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University of Chicago

University of Illinois Chicago

National Jewish Health

University of Colorado Denver

University of Illinois Urbana-Champaign

Illinois College

University of Eastern Finland

University of Miami

Center for Systems Biology

Miami VA Healthcare System

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Proatherogenic Flow Increases Endothelial Stiffness via Enhanced CD36-Mediated Uptake of Oxidized Low-Density Lipoproteins

Arteriosclerosis Thrombosis and Vascular Biology (2017)

Elizabeth Le Master Ru‐Ting Huang Chongxu Zhang Yedida Bogachkov Cassandre Coles

Disturbed flow (DF) is well-known to induce endothelial dysfunction and synergistically with plasma dyslipidemia facilitate plaque formation. Little is known, however, about the synergistic impact of DF and dyslipidemia on endothelial biomechanics. Our goal was to determine the impact of DF on endothelial stiffness and evaluate the role of dyslipidemia/oxLDL (oxidized low-density lipoprotein) in this process.

CD36

Endothelial Dysfunction

Dyslipidemia

Scavenger Receptor

10.1161/atvbaha.117.309907

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