acute flacced paralysis (AFP) cases were reported in 1994～1999 in Hainan Province. The positive isolation rate of non-polio enteroviruses(NPEV)was 27.17%(47/173). Through identification, all of the NPEV could be classified as Coxsackie virus A9(1 case), Coxsackie B2(2 cases), B3(1 case), B6(2 cases)ECHO virus 11 types(31 cases), enterovirus(EV)type 70(1 case), type 71(1 case), Adenovirus? (3 cases). However, the virus strains of 5 AFP cases could not be classified. In the 47 AFP cases, 68 09% of them were male cases. Most of the cases were children of small age groups. The ages of 87 23% cases were smaller than 3 years old. 95 74%(45/47)cases had been immunized with OPV≥3 times. 32 AFP cases who were infected by NPEV only appeared one limb paralysis. 2 of them after 60 days of disease onset had residual paralysis who were infected respectively by ECHO 7 and EV 71 viruses. NPEV infection is one of the important reasons of AFP cases. It should be noticed greatly by clinic doctors, staff of EPI and parents of children. Early diagnosis, early treatment and early recovery should be accomplished.
Case records of hospitalized children (age 4 to 18 years) with acute rheumatic fever on Oahu, HI, were reviewed for the 4-year period from Oct 1, 1980, to Sept 30, 1984. Ninety-eight cases met the modified Jones criteria. The overall incidence of rheumatic fever was 13.4 hospitalized children per 100,000 children per year and that for recurrent attacks was 2.5. Of the 98 with rheumatic fever, 73 had polyarthritis, 33 had carditis, and ten had chorea. Polynesian/part-Polynesian children accounted for 76 of the 98 cases. The incidence of rheumatic fever in Hawaiian/part-Hawaiian was 18.0 and for Samoan children was 206 hospitalized children per 100,000 per year. The relative risks were 7.7 and 88 times that of the white children, respectively. Rheumatic fever continues to cause significant morbidity in children in Hawaii, especially in Polynesian children.
To assess the occurrence of acute rheumatic fever (RF) among the ethnic groups of Hawaii, the case records of hospitalized children with RF in Oahu were reviewed for the period from October 1976 to September 1980. One hundred four of the records met the modified Jones criteria. Incidence rates per 100,000 children were as follows: Japanese, 0; white, 9; Filipino, 9.1; Hawaiian and part-Hawaiian, 27.2; and Samoan, 96.5. Carditis was most common among Samoan children; it occurred in nine of 18 children. A streptococcal, throat culture program for children with respiratory infections was in progress in 60% of Oahu's public schools during this period of time. Children with positive cultures were excluded from school until the start of treatment. However, RF occurred with equal frequency in participating and nonparticipating schools. Rheumatic fever continues to be a substantial problem among Polynesian children in Hawaii, and it is apparent that the school-based primary prevention program used in Hawaii to control streptococcal disease has not altered the frequency of RF among them.
Objective To investigate the risk factors of inflammatory bowel disease(IBD).Methods Totally 150 patients with IBD(IBD group) and the same number of controls(control group) were enrolled between 2007 to 2010 in our hospital.A questionnaire was designed to survey 26 factors including diets,education,occupation,health status.smoking,breast feeding,family history of IBD,history of intestinal infection,appendectomies,measles,use of non-steroidal anti-inflammatory drugs(NSAID).The results were analyzed using multivariate conditional Logistic analysis.Results Multivariate conditional Logistic regression analysis showed that the risk factors of IBD included history of intestinal infection(OR=5.704,95%CI(1.710,10.953)),milk(OR=3.624,95%CI(1.474,8.907)),and mental stress(OR=3.972,95%CI(1.593,12.898)).Sea food significantly reduced the morbidity of IBD(OR=0.78,95%CI(0.121,2.309)).Conclusion Intestinal infection history,milk,and mental stress are the independent risk factors of IBD,and seafood may be a protective factor.
ObjectiveTo investigate the quality of life (QOL) of the epilepsy patients and the factors affected the QOL.Methods200 cases were investigated using the Quality of Life in Epilepsy Inventory 10 (QOLEI 10) and the Washington Psychosocial Seizure Investigate (WPSI). 200 healthy persons were chosen as normal control group. ResultsThe QOL of the patient group were significantly poor as compared with that of normal control group( P0.01). The factors that the patients always faced with were disability in the attack control, short in money, unemployment, restriction of movement, disability in intercommunication, psychological disorder (depress, strain, anxiety, dread, shame feel, cognitional dysfunction, etc.), as well as the difficult to get professional curtains, taking medicine improperly and side effects of the medicine. Conclusions The factors mentioned, which were usually neglected by many doctors, do affect the QOL of epilepsy patients, and hinder the epilepsy treatment effectively.
A case of congenital ankyloglossia (tongue-tie) associated with retruded mandible, glossoptosis, and cleft palate is presented. A surgical procedure is outlined for reconstruction of the tongue-tie condition and complications and their management are discussed.
Objective To dicuss clinical application value of quantitative detection of HBV DNA.Methods HBV DNA was detected by fluorescence quantitative PCR. Results Quantitative range of 285 sample was 1.62 ×10 3～9.42×10 10 with different serum marker models. The patients with HBsAg+ were 275 ( 96.5 %),Only HBcAb+or all HBV M- was 5 respectively (1.75%). Conclusion FQ PCR is useful method for understanding HBV duplication and therapeutic effect.
Objective To study the human papillomavirus type 6/11(HPV6/11) infectious status of patients with vaginitis.Methods Fluoresence quantitative PCR(FQ PCR) was used to measure HPV 6/11-DNA in 258 secretion samples. Results 94 samples were positive with a positive rate of 36.43%. 78 of 94 samples were tesed out over 10 5 copy/ml.Conclusion Middle and old aged patients do not go to hospital until their virus infectious dagree is serious. FQ PCR is suitable for clinical application because of its high sensitivity, rapidity and accuracy.
Five cases are described of acute rheumatic fever meeting the modified Jones criteria with evidence of second or third degree atrioventricular block (AVB). One patient required a temporary transvenous pacemaker and two patients were treated with corticosteroids. One patient had an associated valvulitis. There was no long-term sequelae due to the AVB in any of the patients. The duration of the advanced degree AVB had a range of about 2 to 12 days. The cause of this advanced degree AVB is uncertain. Advanced degree AVB with acute rheumatic fever appears to be self limited in most instances. Unlike rheumatic valvulitis, it is not associated with significant permanent morbidity.
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