Sevim Yener

Ümraniye Eğitim ve Araştırma Hastanesi

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Zİ

Zekeriya İlçe

Ümraniye Eğitim ve Araştırma Hastanesi

Gulam Hekimoğlu

Sağlık Bilimleri Üniversitesi

Nurullah Yücel

Sağlık Bilimleri Üniversitesi

Elif Sena Ozcan

Altınbaş University

Aytekin Kaymakçı

Ümraniye Eğitim ve Araştırma Hastanesi

Metin Eser

Ümraniye Eğitim ve Araştırma Hastanesi

Zİ

Zekeriya İLÇE

Universidad CES

Mehmet Arpacık

Sağlık Bilimleri Üniversitesi

Tayfun Aygün

University of Health Sciences Antigua

Cemile PEHLİVANOĞLU

Ümraniye Eğitim ve Araştırma Hastanesi

Cooperative Institutions

Sağlık Bilimleri Üniversitesi

Ümraniye Eğitim ve Araştırma Hastanesi

University of Health Science

University of Health Sciences

Istanbul University

University of Health Sciences Antigua

Ministry of Health

Istanbul Aydın University

Istanbul Medeniyet University

Universidad CES

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Laparoscopic Bladder Diverticulum Excision in Boys: Three Case Reports

Journal of Urological Surgery (2023)

Sevim Yener Zekeriya İlçe

Bladder diverticula can be congenital or acquired in children.In this study, we present three male patients with congenital bladder diverticulum who underwent laparoscopic diverticulum excision.The main presenting symptoms of the patients were abdominal pain and urinary tract infection.Two patients also had vesicoureteral reflux.Postoperatively, symptoms associated with the urinary system disappeared in all patients.Laparoscopic diverticulum excision is preferred as an effective surgical method in children.

10.4274/jus.galenos.2023.2023-5-1

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Self-Inflicted Intravesical Bobby Pin in a 6 Years Old Boy

Turkiye Klinikleri Journal of Case Reports (2022)

Sevim Yener Cemile PEHLİVANOĞLU Zekeriya İLÇE

Self-inflicted intravesical foreign body is a rare condition in childhood. It is more common in adult patients. Foreign bodies in the bladder can be detected for autoerotic, psychiatric, therapeutic or unclear reasons. In this case, a 6-year-old boy had treatment resistant recurrent urinary tract infection. An opaque body was detected in the pelvic location in the direct urinary system X-ray. An intravesical localized bobby pin was detected on the abdominal ultrasonography. The patient had no previous history of surgical intervention. No additional feature was detected in the physical examination of the patient. There was recurrent urinary tract infection. Infections were resistant to treatment. In the radiological imaging, a bobby pin (wire clip) located in the bladder was detected. It was visualized and removed with cystoscopy.

10.5336/caserep.2021-85827

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Analysis of Various Laparoscopic Pediatric Urology Surgeries: Five-Year Experience of a Single Institution

Cureus (2024)

Sevim Yener Zekeriya İlçe

Background In this study, we aim to report our single-center experience with laparoscopic pediatric urological surgeries. We aim to determine the feasibility of various urological and urogenital laparoscopic procedures and the tricks that increase surgical success. Methodology Data from 98 patients who underwent laparoscopic urological and/or urogenital procedures for diagnostic and therapeutic purposes in our clinic between June 2018 and February 2023 were retrospectively analyzed. All surgeries were performed by the same surgical team. Laparoscopic procedures included orchidopexy, gonadectomy, vaginoplasty, hysterectomy, pyeloplasty, nephrectomy/partial nephrectomy, ureteroneocystostomy, bladder diverticulum excision, renal cyst excision, proximal ureter stone removal, oophorectomy, ovarian detorsion, oophoropexy, and lymph node excision for diagnostic purposes. The surgical planning of the patients was based on the decisions of the pediatric nephrology, pediatric endocrinology, and pediatric oncology departments and the multidisciplinary council. Demographic characteristics of the patients, surgical indications, and intraoperative data, as well as postoperative pathological diagnoses and complications, were recorded. All patients underwent a transperitoneal approach. The duration of the operation was obtained from anesthesia records and defined as the time from the beginning of the surgical incision to the closure of the skin incision. Results Of the patients, 54 were males and 44 were females. The median age was 7.8 years. No complications other than grade 1 according to the Clavien-Dindo classification were observed in our patients. As different types of surgeries were analyzed, the mean operative duration was estimated. Conclusions The laparoscopic method should be performed by surgeons experienced in advanced surgeries in pediatric urology. It is critical to consider the difference in the size of pediatric patients in preparation for laparoscopic surgery to minimize technical and ergonomic problems. We believe that each surgery has its specific tricks and that these should be a part of laparoscopy training. Moreover, developing and sharing this information would be very useful for pediatric urologists.

Pediatric urology

Pyeloplasty

Nephrology

10.7759/cureus.63806

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Copy Number Alterations Associated with Schinzel-Giedion Syndrome: Case Report

Journal of Contemporary Medicine (2024)

Elif Sena Ozcan Gulam Hekimoğlu Sevim Yener Nurullah Yücel

Schinzel-Giedion syndrome (SGS) is a highly recognizable syndrome characterized by severe mental retardation, distinctive facial features, multiple congenital malformations, and higher-level neurological deficits. Comprehending SGS is essential for customized medical treatment, genetic counseling, and furthering developmental problem research. Enhanced understanding leads to better assistance for impacted people and their families, which improves results overall. In this study, we present a case of SGS associated with 2q35-q37 duplication, 4q34.1 duplication, and 9p24.3-24.1 deletion.

10.16899/jcm.1439851

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Gündüz İdrar Kaçırması Olan Çocukların Üriner Sistem Ultrasonografisi, Üroflowmetri ve İşeme Günlüğü Sonuçlarının Değerlendirilmesi

Online Türk Sağlık Bilimleri Dergisi (2023)

Sevim Yener Zekeriya İlçe

Objective: The study aimed to examine the results of urinary system ultrasonography, uroflowmetry, and voiding diary for children with daytime urinary incontinence. Materials and Methods: Patients aged 5-17 with daytime urinary incontinence were retrospectively analysed. Urinary system ultrasonography, uroflowmetry, and a two-day voiding diary were recorded. Comorbid diseases and surgeries were determined using a detailed history. Results: Of the 1805 patients included in the study, 1039 (57.6%) were female, 766 (42.4%) were male, and the mean age was 7.9 ± 2.8 years. Abnormal USG findings were detected in 385 (21.3%) patients. The highest bladder capacity detected in the voiding diary was below the expected bladder capacity in 41.2% of the patients; in comparison, the bladder capacity measured in the uroflowmetry was low in 65.4%. Constipation was the most common in the gastrointestinal system diseases group. In previous surgery, adenoidectomy was the most common procedure. Conclusions: We suggest that these patients should be evaluated not only with bladder USG but also with upper urinary system USG. Pathology can also be detected in the upper urinary system. We think that a well-structured voiding diary provides sufficient data regarding bladder volume instead of bladder volume measured by bladder ultrasonography and/or uroflowmetry.

Abdominal ultrasonography

10.26453/otjhs.1325034

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Bilateral Tek Sistem Ektopik Üreter: Erken Tanı ve Başarılı Tedavi

Online Türk Sağlık Bilimleri Dergisi (2022)

Sevim Yener Aytekin Kaymakçı Zekeriya İlçe

Bilateral tek sistem ektopik üreter(BTSEÜ) ,ürolojideki en nadir durumlardan biridir. Şimdiye kadar 80'den daha az olgu bildirilmiştir. Altta yatan anomaliye göre değişkenlik göstermekle birlikte bu hastalarda inkontinansın yönetimi zordur. Trigon ve mesane boynu bölgesinin yetersiz gelişmesi nedeniyle üriner kontinans ve uzun kuru aralıkların elde edilmesi son derece nadirdir. Burada üriner diversiyona veya mesane boynu rekonstrüksiyonuna gerek kalmadan sadece üreterik reimplantasyon yapılarak tatmin edici üriner kontinans ve mesane kapasitesiyle birlikte normal böbrek fonksiyonları sağlanan BTSEÜ olgusu sunulmuştur.

10.26453/otjhs.1080441

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Cornelia De Lange Syndrome with left heart hypoplasia: a case study

Journal of Emergency Medicine Case Reports (2024)

Elif Sena Ozcan Sevim Yener Gulam Hekimoğlu Nurullah Yücel Zekeriya İlçe

Cornelia de Lange syndrome (CdLS) is characterized by slow growth that can lead to short stature. Despite mutations in the NIPBL, RAD21 or SMC3 genes, CdLS is thought to be inherited in an autosomal dominant manner. Findings include intellectual disability and bone abnormalities in the upper extremities and distinct facial features. It has similar characteristics to autism spectrum disorder, which is a developmental condition that affects communication and social interaction. The physical and clinical findings of a one-and-a-half-year-old girl patient diagnosed with CdLS were reported. In addition to NIPBL gene mutation, atrioventricular septal defect (AVSD), an overriding aorta, and a hypoplastic left heart (HLH) were observed in our case. This study revealed the patient's physical and clinical findings consistent with the diagnosis of CdLS. Additionally emphasized HLH. The importance of performing corrective surgery immediately following the evaluation of congenital heart diseases in CdLS patients can be emphasized.

Growth retardation

Girl

10.33706/jemcr.1395190

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X-Linked Intellectual Disability with NEXMIF Gene Mutation and Developmental Delay with GNAO1 Gene Mutation: Case Report

Medical Research Reports (2024)

Tayfun Aygün Sevim Yener Nurullah Yücel Gulam Hekimoğlu Metin Eser

X-linked intellectual disability (XLID) is a genetically heterogeneous disorder. Currently, 162 genes linked to XLID have been found, but the cause of XLID is still unclear. While the GNAO1 gene is crucial for hypotonia, epilepsy, developmental delay, and movement disorders, the NEXMIF gene, also known as KIAA2022, has associations with XLID, autism, and epilepsy. The subject of the study, a 5-year-old girl has lots of congenital defects, including a cleft palate, anal atresia, hypotonia in her lower limbs, and thumb missing. A variety of eye abnormalities, such as scoliosis, finger malformations, and craniofacial dysmorphism. Radiological tests revealed substantial heart problems, bilateral renal hypoplasia, and brain abnormalities. She met milestones more later than her contemporaries, indicating clear developmental deficits. The NEXMIF and GNAO1 genes both include heterozygous frameshift variants that were discovered through genetic research using next-generation sequencing. The complex and varied clinical signs of XLID are shown in this case. The clinical picture is further complicated by the co-occurrence of mutations in the NEXMIF and GNAO1 genes, which emphasizes the need for an approach to offer suitable therapy solutions. Future studies are necessary to understand the complex interactions between these genes and how they affect XLID and related symptoms.

10.55517/mrr.1439712

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Bebekte Over Sliding Herni Onarımı için İdeal Ameliyat Zamanı

Online Türk Sağlık Bilimleri Dergisi (2022)

Mehmet Arpacık Ceyhan Şahin Fatma Tuğba Güvenç Sevim Yener Aytekin Kaymakçı

Objective: Ovarian sliding hernia is usually operated on emergently or early. Recently, elective surgery has been recommended. However, the ideal time for surgery has not been clarified. The study aims to determine the ideal surgery timing for an infant's ovarian sliding hernias.Materials and Methods: The data of non-reducible inguinal hernia in female infants revived who were operated on at our clinic between 2011 and 2021. The data of ovarian sliding hernias were evaluated for age, clinical findings and surgical outcomes.Results: Of the 76 non-reducible inguinal hernias, 85.5% (n = 65) were found to have sliding hernias of the ovary. The age range of ovarian sliding hernias were 0–3 months 76.9% (n = 50), 3–6 months 23.1% (n = 15) and 6-12 months %0 (n=0). No ovarian torsion was detected in the age group 0-3 months, ovarian torsion was detected in one patient in age group 3–6 months, who also complained of restlessness, swelling in the groin, and tenderness.Conclusion: Although ovarian sliding hernia is more common in 0–3 months, ovarian torsion was not detected in any patient in this period. Surgery for ovarian sliding hernia should be delayed until three months of age.

Groin

10.26453/otjhs.1162059

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