Harun Kılıç

Sakarya University

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Ramazan Akdemir

Sakarya University

115

Sadık Açıkel

University of Health Sciences

Huseyin Gündüz

Sakarya University

Ekrem Yeter

OLVG

Mehmet Doğan

Erzincan University

Murat Aksoy

Sakarya University

Mehmet Bülent Vatan

Sakarya University

Yusuf Can

Sakarya University

ÖK

Özlem Karakurt

Balıkesir University

GÇ

Göksel Çağırcı

Antalya Eğitim ve Araştırma Hastanesi

Cooperative Institutions

Sakarya University

Ministry of Health

Sağlık Bilimleri Üniversitesi

Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi

Hacettepe University

Sakarya Eğitim ve Araştırma Hastanesi

Türkiye Yüksek İhtisas Hastanesi

University of Health Science

State Hospital

Institute of Cardiology

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Yırtılmış sağ koroner Valsalva sinüsü anevrizmasının perkütan yolla kapatılması

Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology (2012)

Ramazan Akdemir Ekrem Yeter Harun Kılıç Ahmet Göktuğ Ertem

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Transcatheter closure of congenital coronary arterial fistulas in adults

Coronary Artery Disease (2008)

Harun Kılıç Ramazan Akdemir Asuman Biçer Mehmet Doğan

Objectives We have described our experience with transcatheter occlusion of congenital coronary arterial fistulas in adults. Methods Six symptomatic patients, mean aged 41±12 years (four men, two women) underwent transcatheter occlusion of fistulas. All had chest pain or dyspnea on exertion. Four of the patients had single fistula. Two of the patients had multiple fistulas. The fistulas originated from the left anterior descending coronary artery in four patients, and from the circumflex artery in two. They all drained into the pulmonary trunk. Graft stenting was used in two patients who had multiple fistulas, and coils in four who had a single fistula. The coils were implanted through a microcatheter, which was passed through a JL 4 8F guiding catheter. Results Coils were used to completely occlude fistulas. Two 3.0×20 mm coronary graft stents were deployed in the coronary arteries to occlude the fistulas. The procedures were uncomplicated. At follow up, all patients underwent coronary angiography, and one of the patients with coil embolization and one of the patients with graft stenting had small residual flow. Patient's chest pain or dyspneas have resolved after the procedure. Conclusion Transcatheter closure in adults of congenital coronary fistulas with graft stents and coils are safe and effective, and can be regarded as an acceptable alternative to surgery.

Closure (psychology)

Cardiac catheterization

10.1097/mca.0b013e3282f19ad8

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Multisided Cardiac Hemangiomas Mimicking Biatrial Thrombus: Atypically Located Cardiac Hemangiomas of Left Atrial Appendage and Right Atrium

Journal of the American Society of Echocardiography (2009)

Sadık Açıkel Mehmet Doğan Ramazan Akdemir Harun Kılıç Asuman Biçer Yeşilay

Appendage

Atrium (architecture)

10.1016/j.echo.2008.12.025

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Association between Epicardial Adipose Tissue Thickness and Left Ventricular Diastolic Functions

Sakarya Medical Journal (2020)

Sabiye Yılmaz Saadet DEMİRTAS INCİ Kahraman Coşansu Huseyin Gündüz Harun Kılıç

Objective: Epicardial adipose tissue (EAT) has been found to be associated with the diastolic dysfunction in recent years, but this relationship has not been fully elucidated. Echocardiography is a non-invasive, simple, cost effective and accessible approach to assess EAT thickness, which can be performed easily. The aim of this study was to evaluate the effectiveness of EAT on prediction of diastolic dysfunction . Materials and Methods: A total of 138 patients without any cardiovascular, inflammatory, autoimmune and cancer disease, were enrolled. Our study was performed in the Cardiology clinic of Sakarya University Training and Research Hospital between May 2019 and December 2019. Subjects were divided into two groups, those with and without diastolic dysfunctions . Conventional echocardiography parameters and tissue Doppler imaging (TDI) were performed to evaluate left ventricular functions. EAT thickness on the free wall of the right ventricle in parasternal long-axis view were measured using transthoracic echocardiography. Results: In comparison with the non- diastolic dysfunction group, patients with diastolic dysfunction had significantly higher epicardial fat thickness (5.98±1.52 mm vs 4.32±1.03 mm; p<0.001). The multivariate regression analysis indicated that EAT independently predicts diastolic dysfunction (OR, 0.278, 95%CI 0.396 to 1.400) Conclusions: According to the findings of this study, EAT thickness is an independent predictor for the development of diastolic dysfunction in patients without cardiovascular disease.

Parasternal line

Tissue Doppler echocardiography

10.31832/smj.732042

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Diabetic Patients Have Increased Perioperative Cardiac Risk in Heart-Type Fatty Acid-Binding Protein-Based Assessment

Medical Principles and Practice (2014)

Münevver Sarı Harun Kılıç Özlem Karakurt Arıtürk Nuray Yazıhan Ramazan Akdemir

Objective: To test the potential role of heart-type fatty acid-binding protein (H-FABP) in detecting increased perioperative cardiac risk in comparison with cardiac troponin I (cTnI) in the early postoperative period. Subjects and Methods: Sixty-seven patients who had clinical risk factors and underwent elective intermediate - or high-risk noncardiac surgery were included in this study. Serum specimens were analyzed for H-FABP and cTnI levels before and at 8 h after surgery. None of the patients had chest pain; 27 had a history of ischemic heart disease, 3 of heart failure, 5 of cerebrovascular diseases, 40 of diabetes and 46 of hypertension. Results: The mean duration of the operations was 2.33 ± 1.27 h (range 1-6). In the postoperative period, 27 (40.3%) patients had increased H-FABP levels (≥7.5 ng/ml); the median preoperative serum H-FABP level was 0.13 ng/ml (<0.1-5.9) and the median postoperative H-FABP level was 6.86 ng/ml (<0.1-13.7). Only 1 (1.5%) patient had cTnI >0.1 µg/l during the postoperative period. Correlation analysis revealed that the presence of diabetes was associated with an increased H-FABP level (r = 0.30, p = 0.01). Of the 27 patients with H-FABP ≥7.5 ng/ml, 21 (87%) had diabetes. There was no significant correlation with other clinical risk factors, type or duration of surgery. Conclusion: The H-FABP levels significantly increased in the postoperative period. Most patients with increased postoperative H-FABP levels were diabetic. High H-FABP levels could alert clinicians to increased perioperative cardiovascular risk and could prevent underdiagnosis, especially in diabetic patients.

10.1159/000368756

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OP-202 [AJC » Percutaneous coronary interventions] A simple Approach to Life-Threatening Complication: Catheter Induced Left Main Coronary Artery Dissection

The American Journal of Cardiology (2017)

Direnç Yılmaz Mehmet Akif Çakar Ersan Tatlı Kahraman Coşansu Yusuf Can

Artery dissection

10.1016/j.amjcard.2017.03.169

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Double trouble for coronary artery flow: Severe aortic valve regurgitation and coronary artery occlusion secondary to intussusception of the intimal flap of aortic dissection

International Journal of Cardiology (2013)

Sadık Açıkel Münevver Sarı Uğursay Kızıltepe Mehmet Doğan Harun Kılıç

Aortic valve regurgitation

10.1016/j.ijcard.2012.12.028

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Psöriazis hastalarında artmıs QT dispersiyonu

Dicle Tıp Dergisi (2010)

Asuman Biçer Nurcan Başar Betül Banu Karasu Özlem Karakurt Harun Kılıç

Objectives: Psoriasis is a chronic infl ammatory skin disorder characterized by erythematous plaques, generally at the elbows, knees, scalp, umbilicus and lumber area. Many systemic diseases including cardiovascular disturbances have been described in psoriatic patients. In the present study, we aimed to investigate QT dispersion (QTD) and corrected QT dispersion (QTcD) as a possible indicator of increased risk for ventricular arrhythmias and sudden cardiac death in patients with psoriasis. Materials and methods: Twenty-three patients with psoriasis and age and gender matched 20 control subjects were enrolled in the study. The severity of the disease was evaluated by the âPsoriasis Area and Severity Index (PASI)â. Standard 12-lead electrocardiographs at 25 mm/s paper speed and 24-hour holter examination were performed in all subjects. QTD and QTcD were measured. QTD was defi ned as the difference between the maximum and minimum QT interval measurements and QTc was calculated according to Bazett\'s formula. Correlation analysis was performed between QTD and QTcD and PASI and duration of the disease. Results: QTD and QTcD were signifi cantly greater in psoriatic patients than controls (QTD, 67.5}17.4 vs 44.0}11.9 ms, p

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Thymosin beta4 levels after successful primary percutaneous coronary intervention for acute myocardial infarction

Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology (2011)

Asuman Biçer Yeşilay Özlem Karakurt Ramazan Akdemir Gönül Erden Harun Kılıç

Thymosin beta4 (Tβ4) has been shown to have an important role in healing of damaged tissues and promoting cardiomyocyte survival in acute coronary syndromes. We evaluated endogenous Tβ4 levels in patients presenting with ST-elevation acute myocardial infarction (STEMI) before and after successful primary percutaneous coronary intervention (PCI).The study included 24 consecutive patients (7 females, 17 males; mean age 55.0±10.9 years) who underwent successful primary PCI for STEMI and 24 age- and sex-matched healthy controls (13 females, 11 males; mean age 57.5±11.7 years) with angiographically normal coronary arteries. To determine Tβ4 levels, blood samples were obtained from STEMI patients on admission and 48 hours after successful PCI, and from controls immediately after coronary angiography.Compared to controls, baseline levels of high-density lipoprotein cholesterol (46.2±8.9 vs. 34.2±7.2 mg/dl, p<0.001) and Tβ4 (2.9±1.5 vs. 1.5±1.0 µg/ml, p<0.001) were significantly lower, and white blood cell counts (7.6±2.2 vs. 11.4±3.0 10³/µl, p<0.001) were significantly higher in the STEMI group. After 48 hours of PCI, the mean Tβ4 level increased significantly to 2.3±0.8 µg/ml (p<0.001) and became similar to that of the control group (p=0.068). There was a significant negative correlation between serum Tβ4 and white blood cell count (r=-0.347, p=0.016).Considering the significant increase in serum Tβ4 levels following successful primary PCI in patients with STEMI, Tβ4 may prove to be a new marker in the assessment of reperfusion success in addition to those used currently.

White blood cell

10.5543/tkda.2011.01751

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Native aortic coarctation stenting in adults and adolescents: early and mid-term results of an adult interventional cardiology team Zabiegi stentowania natywnej koarktacji aorty u dorosłych i nastolatków - wczesne i średnioterminowe wyniki leczenia prowadzonego przez zespół interwencyjnego leczenia kardiologicznego dorosłych

Ramazan Akdemir Hüseyin Gündüz Sani Namık Murat Harun Kılıç Ekrem Yeter

Background: Stent implantation has evolved as an important therapeutic strategy for aortic coarctation. Aim: This study aimed to present the experience of aortic coarctation stenting using the Cheatham-Platinum stent by an Adult Interventional Cardiology Team. Material and methods: The data of 11 patients (ages were between 15 to 58 years) who underwent aortic coarctation stent implan- tation between 2008 and 2011 for moderate to severe native aortic coarctation were retrospectively collected. Results: Average systolic blood pressure was 175 ±35 mm Hg, and mean diastolic blood pressure was 115 ±15 mm Hg. Pressure gradient proximal and distal to aortic coarctation was 55.5 ±17.7 before the stenting. The invasive gradient decreased below 10 mm Hg in all patients. There were no complications except in one patient whose subclavian artery was occluded without any clinical finding. One patient had a totally occluded lesion, needing perforation for acquired interruption using a 0.35 inch hydrophilic wire under the sup- porting balloon. There was no aneurysm or restenosis at follow-up. Left ventricular functions completely recovered within 1 month in all patients. Conclusions: Stenting using the Cheatham-Platinum stent, either covered or bare, is safe in moderate to severe native aortic coarctation and provides an excellent transcoarctation gradient and clinical hypertension and left ventricular functional relief in adult patients.

Interventional cardiology

Perforation

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