Jesús Paredes Cotoré

Universidade de Santiago de Compostela

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Manuel Bustamante Montalvo

Complejo Hospitalario Universitario de Santiago

R. García Figueiras

Complejo Hospitalario Universitario de Santiago

Antonio Gómez‐Caamaño

Instituto de Investigación Sanitaria de Santiago

Patricia Calvo

Complejo Hospitalario Universitario de Santiago

Manuela Gago-Domínguez

Marqués de Valdecilla University Hospital

B. Taboada Valladares

Complejo Hospitalario Universitario de Santiago

David V. Conti

University of Southern California

Polly A. Newcomb

Fred Hutch Cancer Center

Ana Carballo

Complejo Hospitalario Universitario de Santiago

John L. Hopper

University of Melbourne

Cooperative Institutions

Complexo Hospitalario Universitario A Coruña

Servicio Gallego de Salud

Universidade de Santiago de Compostela

Universidade da Coruña

University of Southern California

Fred Hutch Cancer Center

Complejo Hospitalario Universitario de Santiago

Harvard University

Instituto de Investigación Sanitaria de Santiago

Cancer Research Center

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High-dose neoadjuvant radiochemotherapy followed by surgery in MRI and EUS-defined poor-risk rectal cancer

Radiotherapy and Oncology (2011)

J. Iglesias García V. Luna Vega Antonio Gómez‐Caamaño Paula Peleteiro Higuero Ana Carballo

Neoadjuvant Therapy

Chemoradiotherapy

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Rectal cancer surgery

Elsevier eBooks (2021)

Jesús Paredes Cotoré FernandoFernández López Manuel Bustamante Montalvo

Mesorectum

Lymphadenectomy

Resection margin

10.1016/b978-0-323-90055-3.00014-4

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Citations (2)

Genetic Variations in SMAD7 Are Associated with Colorectal Cancer Risk in the Colon Cancer Family Registry

Carolina Digital Repository (University of North Carolina at Chapel Hill) (2013)

Xuejuan Jiang Jose E. Castelao David J. Vandenberg Ãngel Carracedo Carmen M. Redondo

10.17615/b64j-6a48

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Citations (4)

Genetic Variations in SMAD7 Are Associated with Colorectal Cancer Risk in the Colon Cancer Family Registry

PLoS ONE (2013)

Xuejuan Jiang Jose E. Castelao David J. Vandenberg Ãngel Carracedo Carmen M. Redondo

Background Recent genome-wide studies identified a risk locus for colorectal cancer at 18q21, which maps to the SMAD7 gene. Our objective was to confirm the association between SMAD7 SNPs and colorectal cancer risk in the multi-center Colon Cancer Family Registry. Materials and Methods 23 tagging SNPs in the SMAD7 gene were genotyped among 1,592 population-based and 253 clinic-based families. The SNP-colorectal cancer associations were assessed in multivariable conditional logistic regression. Results Among the population-based families, both SNPs rs12953717 (odds ratio, 1.29; 95% confidence interval, 1.12–1.49), and rs11874392 (odds ratio, 0.80; 95% confidence interval, 0.70–0.92) were associated with risk of colorectal cancer. These associations were similar among the population- and the clinic-based families, though they were significant only among the former. Marginally significant differences in the SNP-colorectal cancer associations were observed by use of nonsteroidal anti-inflammatory drugs, cigarette smoking, body mass index, and history of polyps. Conclusions SMAD7 SNPs were associated with colorectal cancer risk in the Colon Cancer Family Registry. There was evidence suggesting that the association between rs12953717 and colorectal cancer risk may be modified by factors such as smoking and use of nonsteroidal anti-inflammatory drugs.

10.1371/journal.pone.0060464

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Citations (18)

Contributors

Elsevier eBooks (2021)

José Francisco Noguera Aguilar Mohammed Alhayek-Aí Pedro A. Alonso Aguirre Paula Álvarez-Chaver Sara Alvarez-Gonzalez

10.1016/b978-0-323-90055-3.09988-9

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Neoadjuvant, adjuvant, and intraoperative radiotherapy for rectal cancer

Elsevier eBooks (2021)

Ana Carballo Paula Peleteiro Higuero B. Taboada Valladares Patricia Calvo Jesús Paredes Cotoré

Neoadjuvant Therapy

Multidisciplinary team

10.1016/b978-0-323-90055-3.00058-2

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Colon cancer surgery

Elsevier eBooks (2021)

FernandoFernández López Jesús Paredes Cotoré Manuel Bustamante Montalvo

Lymphadenectomy

10.1016/b978-0-323-90055-3.00057-0

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Stimulation the Efferent Limb Before Loop Ileostomy Closure With Short Chain Fatty Acids

Cirugía Española (English Edition) (2018)

Fernando López Jaime González-López Manuel Paz Novo María Jesús Ladra González Jesús Paredes Cotoré

Ileostomy

Closure (psychology)

Chain (unit)

10.1016/j.cireng.2018.12.004

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Novel Common Genetic Susceptibility Loci for Colorectal Cancer

WOS (2019)

Stephanie L. Schmit Christopher K. Edlund Fredrick R. Schumacher Jian Gong Tabitha A. Harrison

Background: Previous genome-wide association studies (GWAS) have identified 42 loci (P < 5x10(-8)) associated with risk of colorectal cancer (CRC). Expanded consortium efforts facilitating the d ...

Genetic predisposition

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Resección de GIST rectal mediante cirugía transanal mínimamente invasiva (TAMIS) tras neoadyuvancia con imatinib

Revista Colombiana de Cancerología (2018)

Fernando López María Jesús Ladra González Francisco González Rodríguez Manuel Paz Novo Jesús Paredes Cotoré

10.1016/j.rccan.2017.10.004

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