Fan Di

Beijing University of Chinese Medicine

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Peng Li

Macau University of Science and Technology

Jing Li

Chinese Academy of Medical Sciences & Peking Union Medical College

Min Guan

Chinese Academy of Sciences

Jeff Bruce

Princess Margaret Cancer Centre

Haifeng Zhai

Peking University

Jianmei Huang

Beijing University of Chinese Medicine

Peter J. O’Brien

University College Dublin

Yuerong Zhang

Shanghai Jiao Tong University

Luke Wan

University of Toronto

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University of Toronto

Beijing University of Chinese Medicine

Capital Medical University

Henan Provincial People's Hospital

Zhengzhou University

Canada Research Chairs

Macau University of Science and Technology

Shanxi Agricultural University

Ningxia Medical University General Hospital

Ningxia Medical University

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Effects of estrogen on estrogen receptors gene expression of condylar cartilage of ovariectomized rats

Jichuyixue Yulinchuang (2016)

Min Guan Yuerong Zhang Fan Di Jing Li

Estrogen receptor alpha

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Effects of Dehydroeffusol on Spasmogen-Induced Contractile Responses of Rat Intestinal Smooth Muscles

Planta Medica (2014)

Fan Di Haifeng Zhai Peng Li Jianmei Huang

Dehydroeffusol is a naturally occurring phenanthrene isolated from Juncus effusus. In the context of screening new drugs against gastrointestinal spasms, we investigated its effects on isolated rat jejunum in vitro. Dehydroeffusol (30–90 µM) slightly and transiently enhanced contractions in a concentration-dependent manner but significantly inhibited the contractions induced by KCl (100 mM), (±)-Bay-K8644 (5 µM), pilocarpine (90 µM), and histamine (100 µM). These results show that dehydroeffusol may antagonize the spasmogenic activity of various agents, and therefore, could be a promising agent in the treatment of spasms. Its potential spasmolytic mechanism is also discussed.

10.1055/s-0034-1382901

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Molecular Cytotoxic Mechanisms of Estradiol involve Estradiol Quinoid Moieties

Free Radical Biology and Medicine (2010)

Luke Wan Jeff Bruce Fan Di Peter J. O’Brien

10.1016/j.freeradbiomed.2010.10.632

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Citations (1)