AUREOMYCIN is an antibiotic derived from a strain of Streptomyces aureofaciens. The drug has been found to have a wide antibacterial spectrum against gram-positive and gram-negative organisms. In addition, it has been found to be effective against rickettsia as well as certain viruses, chiefly of the lymphogranuloma-venereum-psittacosis group.1 In man, therapeutic doses up to 60 mg. per kilogram of body weight per day given orally have not been associated with toxic manifestations except for occasional nausea, vomiting and diarrhea. These symptoms have been transient and do not contraindicate or prevent continuation of therapy.Aureomycin is absorbed readily after oral . . .
CHLOROMYCETIN is an antibiotic derived from a strain of Streptomyces venezuelae. Its antimicrobial spectrum is broad and embraces the following organisms: rickettsia, certain viruses of the psittacosis group, gram-positive cocci (including the pneumococcus, streptococcus and staphylococcus) and certain gram-negative organisms including Eberthella typhosa, shigella and several of the coliform group.1 The drug is well tolerated orally, and few toxic reactions have followed its use in therapeutic doses. Chloromycetin is readily absorbed after oral administration, and blood levels of 10 to 40 mg. per 100 cc. are readily obtained when 50 to 100 mg. per kilogram of body weight . . .