Celia Oreja‐Guevara
Universidad Complutense de Madrid
Irene Gómez-Estévez
Hospital Clínico San Carlos
Georgina Arrambide
Universitat Autònoma de Barcelona
Claudia Camacho Grande
Mayra Gómez‐Moreno
Hospital General De Segovia
Paula Tagliani
Universitat Autònoma de Barcelona
María Ruiz‐Ruigómez
Hospital Universitario 12 De Octubre
René Carvajal
Vall d'Hebron Hospital Universitari
Mar Tintoré
Universitat Autònoma de Barcelona
Susana Sainz de la Maza
Instituto Ramón y Cajal de Investigación Sanitaria
'/%3e%3cpath fill='%23c8b100' stroke='none' d='M166.42 264.65c1.99-.72 3.29-1.58 2.66-3.14-.41-1-1.43-1.19-2.97-.63l-2.71.99 2.44 6.03c.27-.12.54-.24.81-.34.28-.1.57-.18.85-.26l-1.08-2.64v-.01zm-1.18-2.91.69-.25c.57-.21 1.21.1 1.5.8.21.53.16 1.13-.5 1.55-.21.13-.46.23-.7.33l-.99-2.43m7.54-2.52c-.29.08-.57.16-.86.22-.29.05-.59.09-.88.12l1.41 6.28 4.38-.88c-.05-.12-.12-.26-.14-.38-.03-.14-.03-.28-.04-.41-.77.22-1.61.46-2.61.66l-1.26-5.61m8.78 5.41c.82-2.28 1.82-4.46 2.81-6.67-.18.03-.36.06-.54.07s-.37.01-.54 0c-.53 1.61-1.18 3.21-1.87 4.8-.82-1.51-1.73-2.99-2.43-4.51-.34.04-.69.09-1.03.12-.34.02-.7.01-1.04.02 1.26 2.06 2.48 4.11 3.64 6.23.16-.03.32-.06.5-.08.16-.01.33.01.5.02m9.16-4.83c.15-.31.31-.6.48-.89-.24-.22-.96-.55-1.81-.63-1.79-.18-2.81.61-2.93 1.69-.26 2.26 3.31 2.07 3.14 3.57-.07.64-.75.9-1.48.83-.81-.08-1.41-.53-1.51-1.19l-.22-.02c-.12.39-.29.77-.48 1.15.53.34 1.21.53 1.85.59 1.83.19 3.22-.54 3.35-1.74.23-2.15-3.37-2.27-3.23-3.54.06-.53.47-.88 1.4-.79.67.07 1.08.43 1.26.95l.18.02m119.58 5.18c.62-2.33 1.41-4.58 2.19-6.87-.17.05-.35.09-.53.11-.17.03-.36.04-.54.05-.37 1.64-.88 3.29-1.42 4.94-.96-1.44-2-2.84-2.83-4.3-.34.07-.68.15-1.02.2s-.69.07-1.04.11c1.45 1.94 2.85 3.89 4.2 5.91.16-.04.32-.1.5-.12.16-.02.33-.02.49-.03m6.18-6.82c-.29.01-.59.04-.88.03-.3 0-.6-.04-.89-.06l-.12 6.41 4.49.08c-.03-.13-.06-.28-.06-.41s.04-.27.07-.4c-.81.05-1.68.1-2.71.08l.1-5.73m7.04 1.05c.72.06 1.41.19 2.1.31-.01-.13-.03-.27-.02-.41.01-.13.06-.26.1-.39l-6.07-.5c.01.14.03.27.02.4-.01.14-.06.27-.1.4.62-.02 1.37-.02 2.21.05l-.53 5.77c.29 0 .59 0 .88.03.3.02.59.07.88.11l.53-5.77m2.49 6.32c.29.05.59.09.88.15.28.06.57.15.85.23l.72-2.94.08.01c.16.41.38.9.49 1.19l.9 2.22c.36.06.71.11 1.05.18.36.08.7.18 1.04.28l-.31-.67c-.48-1-.99-2.01-1.41-3.02 1.12.04 1.98-.36 2.2-1.26.15-.62-.1-1.11-.68-1.53-.44-.31-1.28-.47-1.83-.6l-2.44-.53-1.54 6.29m3.14-5.42c.71.16 1.59.27 1.59 1.07-.01.21-.03.35-.06.48-.23.94-.94 1.26-2.13.91l.6-2.46m8.42 7.35c-.05.69-.18 1.37-.31 2.1.3.14.61.27.9.44.3.16.57.34.86.52l.6-7.23c-.14-.06-.27-.12-.41-.19-.13-.07-.25-.15-.37-.24l-6.38 4.05c.17.08.35.16.51.25.17.09.31.19.47.28.54-.45 1.1-.82 1.74-1.3l2.39 1.31v.01zm-1.81-1.66 2.13-1.37-.25 2.4-1.88-1.03'/%3e%3cpath fill='%23ad1519' stroke-width='.26' d='M249.65 182.72c6.64 0 12.56.99 16.41 2.51 2.2 1 5.16 1.73 8.4 2.17 2.47.33 4.81.39 6.85.24 2.73-.06 6.67.74 10.62 2.48 3.26 1.45 5.99 3.21 7.8 4.91l-1.57 1.4-.45 3.96-4.3 4.92-2.15 1.83-5.09 4.07-2.6.21-.79 2.25-32.91-3.86-33.02 3.86-.79-2.25-2.61-.21-5.08-4.07-2.15-1.83-4.3-4.92-.44-3.96-1.58-1.4c1.82-1.7 4.54-3.46 7.8-4.91 3.95-1.74 7.89-2.54 10.62-2.48 2.04.15 4.38.09 6.85-.24 3.24-.44 6.2-1.17 8.4-2.17 3.86-1.52 9.44-2.51 16.08-2.51z'/%3e%3cg fill='%23c8b100'%3e%3cpath d='m225.34 191.42 1.38 1.11 2.08-3.4c-2.25-1.38-3.8-3.78-3.8-6.51 0-.31.02-.61.06-.91.21-4.34 5.5-7.92 12.2-7.92 3.48 0 6.63.95 8.84 2.48.06-.67.12-1.25.21-1.86-2.43-1.42-5.6-2.28-9.05-2.28-7.71 0-13.74 4.39-14.03 9.57-.03.31-.05.61-.05.92 0 2.76 1.26 5.26 3.26 6.99l-1.1 1.81'/%3e%3cpath d='M225.43 191.46c-2.63-1.97-4.27-4.64-4.27-7.58 0-3.38 2.22-6.4 5.58-8.41-2.07 1.67-3.33 3.83-3.51 6.23-.03.31-.05.61-.05.92 0 2.76 1.26 5.26 3.26 6.99l-1.01 1.85'/%3e%3cpath d='M202.21 194.89c-1.48-1.65-2.38-3.79-2.38-6.12 0-1.41.33-2.75.91-3.95 2.13-4.38 8.82-7.57 16.76-7.57 2.16 0 4.23.23 6.14.67-.42.46-.75.97-1.08 1.48-1.59-.31-3.29-.48-5.06-.48-7.27 0-13.36 2.83-15.12 6.65a7.33 7.33 0 0 0-.73 3.2c0 2.32 1.09 4.4 2.79 5.82l-2.63 4.3-1.41-1.12 1.81-2.88z'/%3e%3cpath d='M204.9 180.48c-1.91 1.21-3.36 2.69-4.16 4.34-.58 1.2-.91 2.54-.91 3.95 0 2.33.9 4.47 2.38 6.12l-1.6 2.59c-1.53-1.96-2.42-4.26-2.42-6.7 0-4.2 2.67-7.87 6.71-10.3zm45.14-9.21c1.76 0 3.28 1.16 3.64 2.73.23 1.38.38 2.95.41 4.62.01.18-.01.35-.01.52 0 .2.04.41.05.61.06 3.52.56 6.62 1.27 8.52l-5.36 5.14-5.43-5.14c.72-1.9 1.22-5 1.29-8.52 0-.2.04-.41.04-.61 0-.17-.01-.34-.01-.52.03-1.67.18-3.24.41-4.62.36-1.57 1.94-2.73 3.7-2.73z'/%3e%3cpath d='M250.04 172.94c.91 0 1.68.58 1.87 1.39.23 1.31.37 2.8.4 4.38 0 .16-.01.32-.01.48 0 .2.03.39.04.59.05 3.32.53 6.25 1.21 8.05l-3.54 3.35-3.54-3.35c.67-1.8 1.15-4.73 1.21-8.05 0-.2.04-.39.04-.59 0-.16-.01-.32-.01-.48.03-1.58.17-3.07.4-4.38.18-.81 1.02-1.39 1.93-1.39zm24.66 18.48-1.39 1.11-2.08-3.4c2.26-1.38 3.81-3.78 3.81-6.51 0-.31-.02-.61-.06-.91-.21-4.34-5.5-7.92-12.2-7.92-3.49 0-6.63.95-8.84 2.48-.06-.67-.12-1.25-.22-1.86 2.44-1.42 5.6-2.28 9.06-2.28 7.71 0 13.74 4.39 14.03 9.57.03.31.05.61.05.92 0 2.76-1.27 5.26-3.27 6.99l1.11 1.81'/%3e%3cpath d='M274.61 191.46c2.63-1.97 4.27-4.64 4.27-7.58 0-3.38-2.22-6.4-5.58-8.41 2.07 1.67 3.33 3.83 3.51 6.23.03.31.05.61.05.92 0 2.76-1.27 5.26-3.27 6.99l1.02 1.85'/%3e%3cpath d='M297.83 194.89c1.47-1.65 2.38-3.79 2.38-6.12 0-1.41-.33-2.75-.91-3.95-2.14-4.38-8.82-7.57-16.76-7.57-2.16 0-4.23.23-6.15.67.43.46.76.97 1.09 1.48 1.58-.31 3.29-.48 5.06-.48 7.27 0 13.35 2.83 15.11 6.65.47.97.73 2.06.73 3.2 0 2.32-1.09 4.4-2.79 5.82l2.63 4.3 1.42-1.12-1.81-2.88z'/%3e%3cpath d='M295.14 180.48c1.91 1.21 3.36 2.69 4.16 4.34.58 1.2.91 2.54.91 3.95 0 2.33-.91 4.47-2.38 6.12l1.6 2.59c1.53-1.96 2.41-4.26 2.41-6.7 0-4.2-2.67-7.87-6.7-10.3z'/%3e%3cellipse cx='250.05' cy='167.3' fill='%23005bbf' stroke-width='.26' rx='4.43' ry='4.2'/%3e%3cpath stroke-width='.26' d='M248.89 155.54v2.26h-2.42v2.3h2.42v6.61h-3.05c-.03.21-.22.37-.22.59 0 .58.12 1.14.35 1.64 0 .02.02.02.03.03h8.12c0-.01.02-.01.03-.03.22-.5.35-1.06.35-1.64 0-.22-.19-.38-.22-.59h-2.96v-6.61h2.42v-2.3h-2.42v-2.26h-2.43z'/%3e%3c/g%3e%3cg fill='%23fff'%3e%3cellipse cx='250.04' cy='188.94' rx='1.91' ry='1.8'/%3e%3cellipse cx='250.04' cy='185.4' rx='1.91' ry='1.8'/%3e%3cellipse cx='250.04' cy='181.6' rx='1.52' ry='1.44'/%3e%3cellipse cx='250.04' cy='178.18' rx='1.1' ry='1.04'/%3e%3cellipse cx='250.04' cy='175.18' rx='.88' ry='.83'/%3e%3cellipse cx='198.94' cy='198.67' rx='1.1' ry='1.04'/%3e%3cellipse cx='197.44' cy='196.02' rx='1.1' ry='1.04'/%3e%3cellipse cx='196.44' cy='192.94' rx='1.1' ry='1.04'/%3e%3cellipse cx='196.31' cy='189.64' rx='1.1' ry='1.04'/%3e%3cellipse cx='197.12' cy='186.4' rx='1.1' ry='1.04'/%3e%3cellipse cx='198.81' cy='183.45' rx='1.1' ry='1.04'/%3e%3cellipse cx='201.06' cy='181.02' rx='1.1' ry='1.04'/%3e%3cellipse cx='203.68' cy='179.01' rx='1.1' ry='1.04'/%3e%3cellipse cx='206.8' cy='177.36' rx='1.1' ry='1.04'/%3e%3cellipse cx='210.04' cy='176.19' rx='1.1' ry='1.04'/%3e%3cellipse cx='213.66' cy='175.54' rx='1.1' ry='1.04'/%3e%3cellipse cx='217.1' cy='175.36' rx='1.1' ry='1.04'/%3e%3cellipse cx='220.47' cy='175.48' rx='1.1' ry='1.04'/%3e%3cellipse cx='224.21' cy='190.32' rx='1.1' ry='1.04'/%3e%3cellipse cx='222.34' cy='187.65' rx='1.1' ry='1.04'/%3e%3cellipse cx='221.35' cy='184.75' rx='1.1' ry='1.04'/%3e%3cellipse cx='221.47' cy='181.57' rx='1.1' ry='1.04'/%3e%3cellipse cx='222.16' cy='178.37' rx='1.1' ry='1.04'/%3e%3cellipse cx='223.84' cy='175.48' rx='1.1' ry='1.04'/%3e%3cellipse cx='226.4' cy='173.47' rx='1.1' ry='1.04'/%3e%3cellipse cx='229.39' cy='171.81' rx='1.1' ry='1.04'/%3e%3cellipse cx='232.7' cy='170.82' rx='1.1' ry='1.04'/%3e%3cellipse cx='236.13' cy='170.23' rx='1.1' ry='1.04'/%3e%3cellipse cx='239.5' cy='170.28' rx='1.1' ry='1.04'/%3e%3cellipse cx='242.99' cy='170.87' rx='1.1' ry='1.04'/%3e%3cellipse cx='246.23' cy='171.99' rx='1.1' ry='1.04'/%3e%3cellipse cx='253.8' cy='171.99' rx='1.1' ry='1.04'/%3e%3cellipse cx='257.04' cy='170.87' rx='1.1' ry='1.04'/%3e%3cellipse cx='260.54' cy='170.28' rx='1.1' ry='1.04'/%3e%3cellipse cx='263.9' cy='170.23' rx='1.1' ry='1.04'/%3e%3cellipse cx='267.34' cy='170.82' rx='1.1' ry='1.04'/%3e%3cellipse cx='270.64' cy='171.81' rx='1.1' ry='1.04'/%3e%3cellipse cx='273.64' cy='173.47' rx='1.1' ry='1.04'/%3e%3cellipse cx='276.19' cy='175.48' rx='1.1' ry='1.04'/%3e%3cellipse cx='277.88' cy='178.37' rx='1.1' ry='1.04'/%3e%3cellipse cx='278.57' cy='181.57' rx='1.1' ry='1.04'/%3e%3cellipse cx='278.69' cy='184.75' rx='1.1' ry='1.04'/%3e%3cellipse cx='277.69' cy='187.65' rx='1.1' ry='1.04'/%3e%3cellipse cx='275.83' cy='190.32' rx='1.1' ry='1.04'/%3e%3cellipse cx='279.57' cy='175.48' rx='1.1' ry='1.04'/%3e%3cellipse cx='282.94' cy='175.36' rx='1.1' ry='1.04'/%3e%3cellipse cx='286.38' cy='175.54' rx='1.1' ry='1.04'/%3e%3cellipse cx='290' cy='176.19' rx='1.1' ry='1.04'/%3e%3cellipse cx='293.24' cy='177.36' rx='1.1' ry='1.04'/%3e%3cellipse cx='296.36' cy='179.01' rx='1.1' ry='1.04'/%3e%3cellipse cx='298.97' cy='181.02' rx='1.1' ry='1.04'/%3e%3cellipse cx='301.22' cy='183.45' rx='1.1' ry='1.04'/%3e%3cellipse cx='302.91' cy='186.4' rx='1.1' ry='1.04'/%3e%3cellipse cx='303.72' cy='189.64' rx='1.1' ry='1.04'/%3e%3cellipse cx='303.6' cy='192.94' rx='1.1' ry='1.04'/%3e%3cellipse cx='302.6' cy='196.02' rx='1.1' ry='1.04'/%3e%3cellipse cx='301.1' cy='198.67' rx='1.1' ry='1.04'/%3e%3c/g%3e%3cg fill='%23c8b100'%3e%3cpath d='M250.15 226.18c-12.26-.02-23.25-1.47-31.09-3.83-.57-.18-.87-.7-.84-1.25-.01-.52.29-1 .84-1.17 7.84-2.36 18.83-3.81 31.09-3.83 12.27.02 23.25 1.47 31.09 3.83.55.17.84.65.83 1.17.03.55-.27 1.07-.83 1.25-7.84 2.36-18.82 3.81-31.09 3.83'/%3e%3cpath d='M250.07 216.09c-12.41.03-23.55 1.58-31.39 4 .65-.31.59-1.12-.22-3.2-.98-2.53-2.5-2.42-2.5-2.42 8.66-2.56 20.73-4.16 34.16-4.18 13.44.02 25.6 1.62 34.27 4.18 0 0-1.53-.11-2.51 2.42-.81 2.08-.87 2.89-.21 3.2-7.84-2.42-19.19-3.97-31.6-4'/%3e%3cpath d='M250.12 210.3c-13.43.02-25.5 1.62-34.16 4.18-.58.17-1.19-.05-1.38-.6s.12-1.18.7-1.35c8.71-2.67 21.08-4.35 34.84-4.38 13.77.03 26.19 1.71 34.9 4.38.58.17.89.8.7 1.35s-.8.77-1.38.6c-8.67-2.56-20.78-4.16-34.22-4.18'/%3e%3cpath d='m250.2 199.78 1.23.22c-.19.5-.24 1.05-.24 1.63 0 2.57 2.21 4.65 4.92 4.65 2.18 0 4.04-1.35 4.67-3.21.08.05.47-1.68.68-1.66.17.02.15 1.8.22 1.77.31 2.34 2.46 3.93 4.87 3.93 2.71 0 4.91-2.08 4.91-4.65 0-.19-.01-.38-.04-.57l1.54-1.52.83 1.94c-.33.61-.46 1.3-.46 2.03 0 2.46 2.1 4.44 4.69 4.44 1.63 0 3.06-.78 3.9-1.97l.99-1.25-.01 1.53c0 1.55.66 2.93 2.16 3.18 0 0 1.73.1 4.03-1.7 2.29-1.8 3.55-3.29 3.55-3.29l.2 1.8s-1.9 2.95-3.97 4.15c-1.14.66-2.86 1.35-4.23 1.13-1.44-.24-2.48-1.4-3.01-2.74-1.03.61-2.25.97-3.55.97-2.81 0-5.33-1.54-6.32-3.86-1.29 1.4-3.09 2.25-5.2 2.25-2.24 0-4.29-1.01-5.57-2.56a7.198 7.198 0 0 1-4.88 1.87c-2.48 0-4.69-1.22-5.94-3.05-1.25 1.83-3.46 3.05-5.94 3.05-1.89 0-3.61-.71-4.87-1.87-1.28 1.55-3.34 2.56-5.58 2.56-2.11 0-3.9-.85-5.19-2.25-1 2.32-3.52 3.86-6.32 3.86-1.31 0-2.52-.36-3.55-.97-.54 1.34-1.57 2.5-3.02 2.74-1.36.22-3.08-.47-4.22-1.13-2.08-1.2-3.98-4.15-3.98-4.15l.2-1.8s1.27 1.49 3.56 3.29c2.29 1.81 4.02 1.7 4.02 1.7 1.51-.25 2.16-1.63 2.16-3.18l-.01-1.53.99 1.25c.84 1.19 2.28 1.97 3.9 1.97 2.59 0 4.69-1.98 4.69-4.44 0-.73-.13-1.42-.46-2.03l.83-1.94 1.54 1.52c-.02.19-.04.38-.04.57 0 2.57 2.2 4.65 4.91 4.65 2.42 0 4.56-1.59 4.88-3.93.06.03.05-1.75.22-1.77.2-.02.6 1.71.67 1.66.64 1.86 2.49 3.21 4.68 3.21 2.71 0 4.91-2.08 4.91-4.65 0-.58-.03-1.13-.24-1.63l1.29-.22'/%3e%3cpath d='M208.37 206.32a2.24 2.24 0 0 0-.72-1.06c-.79-.68-1.84-.79-2.36-.25-.07.07-.13.17-.17.25 0 0-1.11-2.08-2.41-2.78-1.29-.7-3.49-.52-3.49-.52 0-1.6 1.3-2.89 2.99-2.89.99 0 1.92.41 2.48 1.11l.23-1.07s1.36.27 1.98 1.82-.06 3.8-.06 3.8.34-.96.85-1.61c.51-.64 1.81-1.34 2.49-1.66.67-.31 1.37-.79 1.37-.79s.03.18.05.61c.03.51-.01.83-.01.83 1.24-.17 2.69.04 3.83.48-.49.95-1.41 1.84-2.62 2.3 0 0 .44.36.83.75.34.34.44.49.44.49s-.85.13-1.27.19c-.43.05-1.84.28-2.69.22-.62-.04-1.32-.14-1.74-.22'/%3e%3cpath fill='%23ad1519' d='M205.29 205.01c.52-.54 1.57-.43 2.36.25.8.67 1.02 1.66.51 2.19-.51.54-1.57.42-2.36-.25-.79-.68-1.02-1.66-.51-2.19'/%3e%3cpath fill='%23fff' d='M216.39 205.91c-.28-.83-.03-1.65.57-1.83.6-.19 1.32.33 1.6 1.16s.03 1.65-.57 1.84c-.6.18-1.31-.34-1.6-1.17'/%3e%3cpath d='M226.12 201.86c-.33-.27-.59-.64-.67-1.08s.01-.87.23-1.23c0 0-.88-.44-1.83-.69-.72-.19-1.99-.2-2.37-.2-.38-.02-1.15-.03-1.15-.03s.07.17.28.55c.27.46.5.75.5.75-1.27.29-2.35 1.12-3.03 2.09.99.68 2.3 1.1 3.6.97 0 0-.12.34-.2.86-.06.43-.06.61-.06.61s.71-.26 1.07-.39c.35-.13 1.54-.55 2.15-.96.8-.54 1.48-1.25 1.48-1.25'/%3e%3cpath d='M225.68 191.65c1.06.67 1.98 1.79 2.3 3.03 0 0 .13-.25.71-.59.59-.33 1.09-.32 1.09-.32s-.17.97-.25 1.32c-.09.34-.09 1.38-.32 2.32-.23.93-.63 1.68-.63 1.68-.42-.34-.99-.51-1.58-.41-.58.1-1.06.44-1.32.9 0 0-.66-.58-1.21-1.38-.55-.81-.93-1.78-1.13-2.08-.21-.3-.72-1.15-.72-1.15s.47-.18 1.14-.05c.67.12.88.32.88.32-.14-1.28.28-2.62 1.04-3.59'/%3e%3cpath d='M228.97 201.38a1.727 1.727 0 0 0-.42-2.3s.67-.71 1.47-1.26c.6-.41 1.8-.82 2.15-.95.36-.13 1.07-.4 1.07-.4s0 .18-.06.61c-.08.52-.2.87-.2.87 1.3-.14 2.62.29 3.61.98-.69.97-1.77 1.79-3.04 2.08 0 0 .23.28.5.74.21.39.28.56.28.56l-1.15-.03c-.38 0-1.65-.01-2.37-.2-.95-.25-1.84-.69-1.84-.69'/%3e%3cellipse cx='227.37' cy='200.45' fill='%23ad1519' rx='2.17' ry='2.06'/%3e%3cpath fill='%23fff' d='M237.76 201.77c-.11-.87.31-1.63.93-1.7.63-.07 1.23.57 1.34 1.44.11.86-.3 1.63-.93 1.7-.62.07-1.22-.57-1.34-1.44'/%3e%3cpath d='M248.5 199.83c-.32-.36-.53-.82-.53-1.33 0-.5.19-.97.51-1.32 0 0-.89-.67-1.89-1.12-.77-.35-2.18-.59-2.6-.67l-1.28-.24s.04.2.2.67c.2.56.4.93.4.93-1.47.08-2.85.81-3.81 1.76.96.94 2.34 1.66 3.81 1.75 0 0-.2.36-.4.93-.16.46-.2.67-.2.67l1.28-.24c.42-.08 1.83-.32 2.6-.67 1-.46 1.91-1.11 1.91-1.11'/%3e%3cpath d='M250.11 188.36c1.05.95 1.85 2.36 1.95 3.82 0 0 .19-.27.91-.53.73-.26 1.28-.16 1.28-.16s-.39 1.05-.55 1.42c-.17.37-.39 1.53-.84 2.53-.44 1-1.05 1.76-1.05 1.76-.4-.45-1-.75-1.67-.75-.68 0-1.27.3-1.67.75 0 0-.61-.76-1.05-1.76-.45-1-.67-2.16-.84-2.53s-.56-1.42-.56-1.42.56-.1 1.28.16.92.53.92.53c.1-1.46.86-2.87 1.89-3.82'/%3e%3cpath d='M251.76 199.83c.33-.36.53-.82.53-1.33 0-.5-.19-.97-.51-1.32 0 0 .89-.67 1.9-1.12.76-.35 2.17-.59 2.6-.67l1.26-.24s-.02.2-.19.67c-.2.56-.4.93-.4.93 1.47.08 2.86.81 3.81 1.76-.95.94-2.33 1.66-3.81 1.75 0 0 .2.36.4.93.16.46.19.67.19.67l-1.26-.24c-.43-.08-1.84-.32-2.6-.67-1.01-.46-1.92-1.11-1.92-1.11'/%3e%3cellipse cx='250.14' cy='198.5' fill='%23ad1519' rx='2.17' ry='2.06'/%3e%3cpath fill='%23fff' d='M262.58 201.77c.11-.87-.3-1.63-.93-1.7s-1.23.57-1.34 1.44c-.11.86.31 1.63.93 1.7.63.07 1.23-.57 1.34-1.44'/%3e%3cpath d='M271.38 201.38c-.22-.35-.32-.79-.25-1.23.09-.44.33-.81.67-1.07 0 0-.67-.71-1.47-1.26-.61-.41-1.8-.82-2.16-.95-.35-.13-1.06-.4-1.06-.4s-.01.18.06.61c.08.52.19.87.19.87-1.29-.14-2.61.29-3.6.98.68.97 1.77 1.79 3.03 2.08 0 0-.23.28-.49.74-.22.39-.28.56-.28.56l1.14-.03c.38 0 1.66-.01 2.37-.2.95-.25 1.84-.69 1.84-.69'/%3e%3cpath d='M274.67 191.65c-1.06.67-1.98 1.79-2.31 3.03 0 0-.12-.25-.71-.59-.58-.33-1.09-.32-1.09-.32s.17.97.26 1.32c.09.34.09 1.38.31 2.32.23.93.64 1.68.64 1.68.42-.34.99-.51 1.57-.41.59.1 1.06.44 1.33.9 0 0 .66-.58 1.21-1.38.54-.81.92-1.78 1.12-2.08.21-.3.72-1.15.72-1.15s-.47-.18-1.14-.05c-.67.12-.88.32-.88.32.15-1.28-.28-2.62-1.03-3.59'/%3e%3cpath d='M274.22 201.86c.34-.27.6-.64.67-1.08.09-.44 0-.87-.22-1.23 0 0 .88-.44 1.83-.69.72-.19 1.99-.2 2.36-.2.39-.02 1.15-.03 1.15-.03s-.06.17-.28.55c-.26.46-.49.75-.49.75 1.26.29 2.34 1.12 3.03 2.09-.99.68-2.31 1.1-3.6.97 0 0 .11.34.19.86.06.43.06.61.06.61s-.71-.26-1.06-.39c-.36-.13-1.55-.55-2.16-.96-.79-.54-1.48-1.25-1.48-1.25'/%3e%3cellipse cx='272.98' cy='200.45' fill='%23ad1519' rx='2.17' ry='2.06'/%3e%3cpath fill='%23fff' d='M283.96 205.91c.28-.83.03-1.65-.57-1.83-.6-.19-1.32.33-1.61 1.16-.28.83-.03 1.65.57 1.84.6.18 1.32-.34 1.61-1.17'/%3e%3cpath d='M291.97 206.32c.11-.37.36-.75.72-1.06.79-.68 1.85-.79 2.36-.25.07.07.14.17.18.25 0 0 1.1-2.08 2.4-2.78s3.5-.52 3.5-.52c0-1.6-1.31-2.89-3-2.89-.99 0-1.92.41-2.47 1.11l-.23-1.07s-1.36.27-1.98 1.82.05 3.8.05 3.8-.33-.96-.84-1.61c-.51-.64-1.81-1.34-2.49-1.66-.68-.31-1.37-.79-1.37-.79s-.03.18-.06.61c-.02.51.02.83.02.83-1.25-.17-2.7.04-3.83.48.48.95 1.4 1.84 2.61 2.3 0 0-.43.36-.83.75-.33.34-.43.49-.43.49s.85.13 1.27.19c.43.05 1.84.28 2.68.22.63-.04 1.32-.14 1.74-.22'/%3e%3cpath fill='%23ad1519' d='M295.05 205.01c-.51-.54-1.57-.43-2.36.25-.79.67-1.02 1.66-.51 2.19.51.54 1.57.42 2.36-.25.79-.68 1.02-1.66.51-2.19'/%3e%3c/g%3e%3cg fill='none'%3e%3cpath fill='%23ad1519' stroke-linejoin='round' d='M250.12 224.57c-11.06-.01-21.07-1.29-28.68-3.26 7.61-1.97 17.62-3.17 28.68-3.19 11.07.02 21.13 1.22 28.74 3.19-7.61 1.97-17.67 3.25-28.74 3.26z'/%3e%3cpath stroke-width='.05' d='M258.04 224.28v-6.01m-3.02 6.21.04-6.37m-2.24 6.45v-6.49'/%3e%3cpath stroke-width='.09' d='M250.95 224.64v-6.57'/%3e%3cpath stroke-width='.14' d='M249.16 224.64v-6.57'/%3e%3cpath stroke-width='.18' d='M247.48 224.64v-6.57'/%3e%3cpath stroke-width='.23' d='M245.81 224.64v-6.57'/%3e%3cpath stroke-width='.28' d='M244.32 224.64v-6.57'/%3e%3cpath stroke-width='.33' d='m241.48 224.28-.04-5.97m1.39 6.05v-6.25'/%3e%3cpath stroke-width='.37' d='M238.86 224.01v-5.5m1.33 5.66-.04-5.86'/%3e%3cpath stroke-width='.42' d='M235.35 223.7v-4.84m1.15 4.92v-5.08m1.19 5.24v-5.28'/%3e%3cpath stroke-width='.46' d='M234.12 223.66v-4.68'/%3e%3cpath stroke-width='.51' d='M232.97 223.42v-4.36'/%3e%3cpath stroke-width='.56' d='M231.74 223.31v-4.06'/%3e%3cpath stroke-width='.6' d='m229.22 222.95-.04-3.22m1.33 3.38v-3.62'/%3e%3cpath stroke-width='.63' d='M227.93 222.68v-2.84'/%3e%3cpath stroke-width='.68' d='M226.74 222.45v-2.36'/%3e%3cpath stroke-width='.73' d='M225.45 222.13v-1.85'/%3e%3cpath stroke-width='.77' d='M224.12 221.98v-1.38'/%3e%3cpath stroke-width='.91' d='M222.72 221.66v-.67'/%3e%3cpath d='M220.12 221.66c7.75-2.18 18.29-3.52 30-3.54 11.72.02 22.31 1.36 30.06 3.54'/%3e%3cpath fill='%23ad1519' d='m216.72 217.16 1.22-1.59 3.37.43-2.69 1.96-1.9-.8'/%3e%3cpath fill='%23fff' d='M224.03 215.28c0-.58.49-1.04 1.1-1.04s1.1.46 1.1 1.04c0 .57-.49 1.04-1.1 1.04s-1.1-.47-1.1-1.04'/%3e%3cpath fill='%23058e6e' d='m233.64 215.07-2.36.27c-.61.07-1.17-.33-1.24-.9-.08-.57.35-1.09.96-1.15l2.37-.28 2.42-.28c.6-.07 1.15.33 1.22.9s-.36 1.09-.96 1.16l-2.41.28'/%3e%3cpath fill='%23fff' d='M240.54 213.35c0-.58.49-1.04 1.1-1.04.6 0 1.1.46 1.1 1.04 0 .57-.5 1.04-1.1 1.04-.61 0-1.1-.47-1.1-1.04'/%3e%3cpath fill='%23ad1519' d='M250.15 214.16h-3.29c-.6 0-1.11-.46-1.11-1.03 0-.58.49-1.04 1.1-1.04h6.64c.61 0 1.1.46 1.1 1.04 0 .57-.51 1.03-1.11 1.03h-3.33'/%3e%3cpath fill='%23fff' d='M257.56 213.35c0-.58.5-1.04 1.1-1.04.61 0 1.1.46 1.1 1.04 0 .57-.49 1.04-1.1 1.04-.6 0-1.1-.47-1.1-1.04'/%3e%3cpath fill='%23058e6e' d='m266.66 215.07 2.36.27c.6.07 1.17-.33 1.24-.9s-.36-1.09-.96-1.15l-2.37-.28-2.42-.28c-.61-.07-1.15.33-1.22.9-.08.57.36 1.09.96 1.16l2.41.28'/%3e%3cpath fill='%23fff' d='M274.07 215.28c0-.58.49-1.04 1.1-1.04s1.1.46 1.1 1.04c0 .57-.49 1.04-1.1 1.04s-1.1-.47-1.1-1.04'/%3e%3cpath fill='%23ad1519' d='m283.57 217.16-1.21-1.59-3.37.43 2.69 1.96 1.89-.8'/%3e%3c/g%3e%3cg stroke-width='.52'%3e%3cpath fill='%23ccc' d='M250.49 344.33c-13.08 0-26.05-3.2-36.95-8.54-8.03-3.98-13.36-12-13.36-21.19v-33.3H300.6v33.3c0 9.19-5.32 17.21-13.36 21.19-10.9 5.34-23.66 8.54-36.75 8.54z'/%3e%3cpath fill='%23ffd691' d='M252.91 329.55c2.09.63 3.15 2.19 3.15 4.01 0 2.38-2.3 4.18-5.3 4.18-2.99 0-5.42-1.8-5.42-4.18 0-1.79 1-3.8 3.08-3.94 0 0-.06-.19-.24-.5-.22-.23-.64-.66-.64-.66s.79-.15 1.25.02c.46.18.77.47.77.47s.21-.43.52-.76c.3-.33.7-.53.7-.53s.46.38.61.64c.15.27.25.59.25.59s.42-.35.79-.49c.37-.15.84-.26.84-.26s-.13.46-.22.69-.14.72-.14.72'/%3e%3cpath fill='%23058e6e' d='M250.32 340.32s-3.98-2.68-5.7-3.04c-2.21-.47-4.69-.09-5.76-.15.03.03 1.29.93 1.84 1.48s2.39 1.65 3.43 1.91c3.22.81 6.19-.2 6.19-.2m1.14.24s2.54-2.66 5.21-3.02c3.15-.44 5.22.26 6.44.58.03 0-1.01.49-1.56.87-.55.37-1.97 1.57-4.14 1.59-2.18.03-4.58-.23-4.97-.17-.4.06-.98.15-.98.15'/%3e%3cpath fill='%23ad1519' d='M250.69 337.28c-1-.93-1.62-2.25-1.62-3.72 0-1.46.62-2.78 1.63-3.71a5.08 5.08 0 0 1-.01 7.43'/%3e%3cpath fill='%23058e6e' d='M249.68 342.71s.61-1.52.67-2.83c.06-1.09-.15-2.17-.15-2.17h.8s.39 1.16.39 2.17c0 1.02-.18 2.37-.18 2.37s-.55.08-.73.17c-.19.09-.8.29-.8.29'/%3e%3cg fill='%23c8b100'%3e%3cpath fill='%23ad1519' d='M250.32 314.57c0 13.16-11.16 23.82-25.05 23.82s-25.15-10.66-25.15-23.82v-33.35h50.2v33.35'/%3e%3cpath d='M200.03 314.12c.15 7.02 2.95 12.25 5.73 15.67v-49.47h-5.66l-.07 33.8zm11.05 20.11c1.57.83 3.72 2.22 6.03 2.77l-.15-56.96h-5.88v54.19zm11.2 4.02c2.3.23 4.01.19 5.87 0v-58.21h-5.87v58.21zm11.04-1.25c2.3-.46 4.9-1.89 6.03-2.63v-54.33h-5.88l-.15 56.96zm11.49-7.76c2.45-2.18 4.75-7.12 5.59-12.76l.14-36.44h-5.87l.14 49.2z'/%3e%3c/g%3e%3cpath fill='%23ad1519' d='M300.65 281.22v33.35c0 13.16-11.28 23.82-25.17 23.82-13.9 0-25.16-10.66-25.16-23.82v-33.35h50.33'/%3e%3cpath id='e' fill='%23c8b100' stroke='%23c8b100' stroke-width='.26' d='M272.71 306.14c.05-.14.12-.27.19-.4l-4.26-4.74-1.67.72-3.06-3.39 1-1.46-5.34-5.99c-.07.02-.2.02-.27.04l.03 4.02 1.75.5v4.46l-1.75.48-.03 4.08c.84.26 1.48.88 1.74 1.67l3.21.01.51-1.67h4.72l.5 1.67zm-6.98-18.5v1.61h2.76v-1.61zm-7.3 20.37c.64 0 1.16-.49 1.16-1.1s-.52-1.11-1.16-1.11c-.65 0-1.17.5-1.17 1.11s.52 1.1 1.17 1.1zm15.99-9.73-1.76-.48v-4.46l1.76-.5-.01-1.92c-.85-.25-1.51-.87-1.79-1.67h-2.68l-.51 1.67h-4.71l-.51-1.67h-3.09c-.08.22-.17.42-.29.61l5.38 5.96 1.67-.71 3.06 3.4-1 1.45 4.18 4.64c.09-.04.18-.08.28-.12zm-7.25-1.39-1.29 1.04 1.77 1.98 1.29-1.05zm8.004 36.186c-1.24-.065-2.255-.902-2.514-2.016-1.67-.23-3.25-.66-4.73-1.3l.84-1.43c1.29.55 2.66.91 4.08 1.11.31-.66.86-1.16 1.58-1.4l.01-5.62-1.76-.49v-4.46l1.76-.48v-7.64a.882.882 0 0 1-.2-.09l-3.98 4.42 1 1.44-3.06 3.4-1.67-.71-3.3 3.67c.57.87.55 2-.11 2.85a15.58 15.58 0 0 0 3.24 2.75l-.84 1.44c-1.42-.89-2.7-1.99-3.79-3.22-.87.26-1.86.11-2.6-.5-1.15-.93-1.29-2.56-.3-3.64l.14-.16c-.69-1.56-1.16-3.24-1.32-5l1.71.01c.14 1.5.51 2.93 1.09 4.27.49-.06 1-.01 1.46.16l3.32-3.68-1-1.45 3.06-3.4 1.67.72 3.99-4.43a2.15 2.15 0 0 1-.21-.46l-2.76.01-.5 1.67h-4.72l-.51-1.67-3.24-.01c-.27.76-.9 1.36-1.69 1.62l-.01 4.04-1.71-.01v-4.01c-1.1-.33-1.91-1.31-1.91-2.47 0-1.15.82-2.15 1.92-2.48l.01-4.05-1.76-.48v-4.46l1.76-.5v-4.05c-1.08-.35-1.84-1.32-1.84-2.45 0-1.43 1.22-2.58 2.73-2.58 1.22 0 2.25.74 2.61 1.78h3.09l.51-1.67h4.71l.51 1.67h2.68c.357-1.031 1.363-1.767 2.559-1.78l.071 8.37h-.85v2.61h.845l-.021 21.59h-.784v2.61h.78zm-5.914-18.306-1.29-1.04-1.78 1.98 1.29 1.04zm-9.96-18.44h-1.69l-.01 2.61h1.7zm9.16 11.41v-1.6h-2.85v1.6zm-10.6 9.69-1.76-.39-.25-4.45 1.75-.58v2.56c0 .99.09 1.92.26 2.86zm1.46-5.52 1.75.41s.09 2.87.05 2.22c-.04-.74.19 2.24.19 2.24l-1.76.58c-.18-.9-.24-1.84-.24-2.79zm10.81 16.93.39-1.7c-1.52-.48-2.93-1.18-4.17-2.09l-1.26 1.11c1.48 1.15 3.19 2.08 5.04 2.68zm-.85 1.44-1.3 1.22c-1.47-.54-2.86-1.26-4.12-2.11l.38-1.77c1.5 1.13 3.21 2.03 5.04 2.66z'/%3e%3cuse xlink:href='%23e' transform='matrix(-1 0 0 1 550.43 0)'/%3e%3cpath fill='%23058e6e' stroke='none' d='M272.59 306.94c0-1.44 1.23-2.6 2.74-2.6s2.73 1.16 2.73 2.6c0 1.43-1.22 2.58-2.73 2.58s-2.74-1.15-2.74-2.58'/%3e%3cg fill='%23c8b100' stroke-width='.46'%3e%3cpath fill='%23ad1519' stroke-width='.52' d='M200.12 281.25h50.18v-55.72h-50.18v55.72z'/%3e%3cpath d='M217.34 238.41h-.92v-.92h-1.62v3.69h1.62v2.55h-3.47v7.39h1.85v14.79h-3.7v7.63h28.42v-7.63h-3.69v-14.79h1.85v-7.39h-3.47v-2.55h1.62v-3.69h-1.62v.92h-.93v-.92h-1.61v.92h-1.16v-.92h-1.62v3.69h1.62v2.55h-3.46v-8.09h1.84v-3.7h-1.84v.93h-.93v-.93h-1.62v.93h-.92v-.93h-1.85v3.7h1.85v8.09h-3.47v-2.55h1.62v-3.69h-1.62v.92h-.92v-.92h-1.85v.92zm-6.24 35.13h28.42m-28.42-1.85h28.42m-28.42-1.85h28.42m-28.42-1.85h28.42m-28.42-2.08h28.42m-24.72-1.62h21.03m-21.03-1.85h21.03m-21.03-2.08h21.03m-21.03-1.84h21.03m-21.03-1.85h21.03m-21.03-1.85h21.03m-21.03-1.85h21.03m-22.88-1.85h24.73m-24.73-1.85h24.73m-24.73-1.85h24.73m-24.73-1.84h24.73m-21.26-1.85h17.79m-10.63-1.85h3.47m-3.47-1.85h3.47m-3.47-1.85h3.47m-3.47-1.85h3.47m-5.32-2.31h7.16m-12.47 7.86h3.69m-5.31-2.31h6.93m-6.93 33.97v-1.85m0-1.85v-1.85m-1.85 1.85v1.85m3.47 0v-1.85m1.84 3.7v-1.85m0-1.85v-1.85m0-2.08v-1.62m0-1.85v-2.08m-1.84 7.63v-2.08m-3.47 2.08v-2.08m7.16 0v2.08m1.62-2.08v-1.62m-5.31-1.85v1.85m3.69-1.85v1.85m3.47-1.85v1.85m-1.85-1.85v-2.08m1.85-1.84v1.84m0-5.54v1.85m-1.85-3.7v1.85m1.85-3.7v1.85m-3.47-1.85v1.85m-3.69-1.85v1.85m-1.62-3.7v1.85m3.46-1.85v1.85m3.47-1.85v1.85m1.85-3.7v1.85m-3.47-1.85v1.85m-3.69-1.85v1.85m-1.62-3.69v1.84m6.93-1.84v1.84m-3.47-5.54v1.85m15.95-1.85h-3.7m5.32-2.31h-6.94m6.94 33.97v-1.85m0-1.85v-1.85m1.85 1.85v1.85m-3.47 0v-1.85m-1.85 3.7v-1.85m0-1.85v-1.85m0-2.08v-1.62m0-1.85v-2.08m1.85 7.63v-2.08m3.47 2.08v-2.08m-7.17 0v2.08m-1.62-2.08v-1.62m5.32-1.85v1.85m-3.7-1.85v1.85m-3.46-1.85v1.85m1.84-1.85v-2.08m-1.84-1.84v1.84m0-5.54v1.85m1.84-3.7v1.85m-1.84-3.7v1.85m3.46-1.85v1.85m3.7-1.85v1.85m1.62-3.7v1.85m-3.47-1.85v1.85m-3.47-1.85v1.85m-1.84-3.7v1.85m3.46-1.85v1.85m3.7-1.85v1.85m1.62-3.69v1.84m-6.94-1.84v1.84m3.47-5.54v1.85m-7.16 18.71v-2.08m0-5.54v-1.85m0 5.55v-1.85m0-5.55v-1.85m0-1.85v-1.84m0-3.7v-1.85m0-1.85v-1.85m-8.78 4.85h3.69m3.47-5.54h3.47m3.46 5.54h3.7'/%3e%3cpath d='M230.05 273.54v-4.86c0-.92-.46-3.7-4.85-3.7-4.16 0-4.62 2.78-4.62 3.7v4.86h9.47z'/%3e%3cpath d='m222.19 268.91-2.31-.23c0-.92.23-2.31.93-2.77l2.08 1.62c-.23.23-.7.92-.7 1.38zm3.93-2.31 1.16-2.08c-.46-.23-1.39-.46-2.08-.46-.46 0-1.39.23-1.85.46l1.15 2.08h1.62zm2.31 2.31 2.31-.23c0-.92-.23-2.31-.92-2.77l-2.08 1.62c.23.23.69.92.69 1.38zm-6.7-8.08v-5.09c0-1.38-.92-2.54-2.54-2.54s-2.54 1.16-2.54 2.54v5.09h5.08zm7.16 0v-5.09c0-1.38.93-2.54 2.55-2.54 1.61 0 2.54 1.16 2.54 2.54v5.09h-5.09zm-8.78-12.48.23-4.62h-4.39l.47 4.62h3.69zm6.94 0 .46-4.62h-4.39l.23 4.62h3.7zm3.46 0-.46-4.62h4.62l-.46 4.62h-3.7z'/%3e%3cpath fill='%230039f0' stroke='none' d='M228.43 273.54v-4.16c0-.7-.46-2.78-3.23-2.78-2.54 0-3.01 2.08-3.01 2.78v4.16h6.24zm-7.16-13.18v-4.39c0-1.15-.69-2.31-2.08-2.31s-2.08 1.16-2.08 2.31v4.39h4.16zm8.09 0v-4.39c0-1.15.69-2.31 2.08-2.31 1.38 0 2.08 1.16 2.08 2.31v4.39h-4.16z'/%3e%3c/g%3e%3cpath fill='%23ccc' d='M250.28 281.25h50.32v-55.72h-50.32v55.72z'/%3e%3cpath fill='%23db4446' stroke-width='.39' d='m275.93 239.26.05-.62.09-.34s-1.61.13-2.46-.11-1.61-.59-2.4-1.25c-.79-.68-1.1-1.1-1.67-1.18-1.36-.22-2.4.4-2.4.4s1.02.37 1.78 1.31 1.59 1.41 1.95 1.53c.59.18 2.66.05 3.22.07.57.03 1.84.19 1.84.19z'/%3e%3cg fill='none' stroke-width='.39'%3e%3cpath fill='%23ed72aa' d='M283.46 237s.01.72.08 1.4c.06.67-.22 1.24-.11 1.61s.16.66.3.93c.14.26.21.94.21.94s-.38-.28-.74-.54c-.35-.27-.6-.44-.6-.44l.1 1.03c.04.31.22.89.51 1.24.29.33.87.89 1.05 1.33.18.45.14 1.44.14 1.44s-.46-.75-.87-.89c-.39-.14-1.26-.62-1.26-.62s.79.79.79 1.55c0 .75-.32 1.6-.32 1.6s-.36-.68-.83-1.12c-.47-.45-1.13-.9-1.13-.9s.52 1.17.52 1.95c0 .79-.15 2.47-.15 2.47s-.39-.64-.79-.96c-.4-.31-.87-.58-1.02-.78-.14-.21.48.64.54 1.16.07.51.32 2.35 1.92 4.69.94 1.37 2.39 3.77 5.5 2.98 3.11-.78 1.96-4.97 1.3-6.92-.65-1.95-.98-4.11-.94-4.87.04-.75.58-2.97.51-3.39-.07-.41-.24-2 .14-3.28.4-1.33.73-1.85.95-2.4.21-.55.39-.86.46-1.34s.07-1.37.07-1.37.58 1.06.73 1.44c.14.38.14 1.5.14 1.5s.11-1.12.98-1.67 1.88-1.13 2.13-1.44.33-.51.33-.51-.08 1.92-.62 2.67c-.36.49-1.77 2.09-1.77 2.09s.73-.28 1.23-.3c.51-.04.87 0 .87 0s-.62.48-1.41 1.64c-.8 1.16-.47 1.26-1.05 2.22s-1.05 1-1.78 1.58c-1.08.87-.5 4.34-.36 4.86.15.51 2.03 4.76 2.07 5.79.03 1.03.21 3.33-1.6 4.8-1.16.95-3.07.96-3.51 1.23-.43.28-1.29 1.13-1.29 2.91 0 1.79.64 2.06 1.15 2.51.51.44 1.16.2 1.3.55.15.34.22.54.44.75.21.2.36.44.29.82-.08.38-.91 1.23-1.2 1.85-.29.61-.87 2.23-.87 2.47s-.07.99.18 1.37c0 0 .91 1.06.29 1.26-.4.14-.78-.25-.97-.2-.54.14-.83.47-.98.45-.36-.07-.36-.25-.4-.76-.03-.51-.01-.72-.17-.72-.22 0-.33.18-.37.45s-.04.89-.29.89-.61-.45-.83-.55-.83-.2-.87-.48c-.03-.27.36-.85.76-.96.4-.1.76-.3.51-.51-.26-.2-.51-.2-.76 0-.25.21-.79.04-.76-.27.04-.31.11-.69.07-.86-.03-.17-.47-.51.1-.82.59-.31.84.27 1.42.17s.86-.31 1.08-.65.18-1.06-.22-1.5c-.39-.45-.79-.52-.94-.8-.14-.27-.36-.92-.36-.92s.11 1.2.04 1.37-.04.89-.04.89-.39-.45-.72-.79c-.32-.34-.65-1.37-.65-1.37s-.03.96-.03 1.34c0 .37.43.72.29.86-.15.13-.83-.72-1.02-.86-.18-.14-.76-.58-1.01-1.06s-.44-1.16-.51-1.41c-.07-.24-.19-1.31-.07-1.58.18-.4.47-1.13.47-1.13h-1.41c-.76 0-1.3-.23-1.59.28s-.15 1.54.21 2.88c.37 1.33.58 1.98.48 2.22-.11.24-.58.79-.76.89-.19.11-.69.07-.91-.03-.21-.1-.57-.27-1.26-.27s-1.12.03-1.37-.03c-.26-.07-.88-.38-1.17-.31s-.79.32-.65.72c.22.61-.21.75-.51.72-.29-.04-.53-.14-.9-.24-.36-.11-.9 0-.83-.42.07-.41.22-.44.4-.74.18-.32.25-.52.04-.54-.25-.02-.51-.05-.7.11-.2.16-.51.51-.76.38-.26-.14-.46-.43-.46-1.08 0-.64-.68-1.2-.05-1.17.62.03 1.41.48 1.55.13s.06-.51-.28-.78-.76-.43-.31-.77c.45-.35.56-.35.74-.54.17-.18.41-.79.73-.64.62.3.02.73.65 1.42.62.69 1.01.94 2.06.83 1.04-.11 1.33-.24 1.33-.54 0-.29-.09-.82-.12-1.04-.02-.21.15-.99.15-.99s-.48.3-.63.59c-.13.29-.42.8-.42.8s-.11-.6-.08-1.09c.02-.29.12-.79.11-.89-.03-.27-.23-.94-.23-.94s-.16.73-.28.94c-.11.21-.16 1.07-.16 1.07s-.67-.58-.48-1.55c.13-.75-.12-1.74.11-2.06.22-.33.75-1.64 2.06-1.69 1.3-.05 2.31.05 2.77.03.45-.03 2.06-.33 2.06-.33s-2.97-1.52-3.64-1.98c-.68-.45-1.73-1.63-2.07-2.16-.34-.54-.65-1.58-.65-1.58s-.53.02-1.02.29c-.48.27-.96.67-1.24.99s-.73 1.05-.73 1.05.08-.94.08-1.23-.06-.86-.06-.86-.33 1.28-1.01 1.76c-.68.49-1.47 1.15-1.47 1.15s.08-.71.08-.88c0-.16.17-.99.17-.99s-.48.72-1.21.86c-.74.13-1.81.11-1.9.56-.08.45.2 1.07.03 1.39s-.54.54-.54.54-.42-.35-.79-.38c-.36-.03-.71.16-.71.16s-.31-.4-.19-.67c.11-.26.67-.66.54-.83-.15-.16-.6.06-.88.19-.28.14-.88.27-.82-.19.05-.45.2-.72.05-1.04-.14-.32-.05-.53.18-.61.22-.08 1.12.02 1.21-.19.08-.21-.22-.48-.82-.61-.59-.14-.88-.49-.57-.78.32-.3.4-.38.54-.64.14-.27.2-.76.74-.51.53.24.42.83.99 1.01.56.19 1.89-.08 2.17-.24s1.19-.83 1.5-.99c.31-.15 1.61-1.12 1.61-1.12s-.76-.53-1.05-.8c-.28-.27-.78-.91-1.04-1.05-.25-.13-1.5-.61-1.92-.64-.42-.02-1.72-.48-1.72-.48s.59-.19.79-.35c.19-.16.64-.56.87-.53.22.02.28.02.28.02s-1.21-.05-1.47-.13c-.25-.08-.99-.54-1.27-.54s-.84.11-.84.11.76-.48 1.38-.59c.62-.1 1.1-.08 1.1-.08s-.96-.27-1.19-.58c-.22-.33-.45-.8-.62-1.02-.17-.21-.28-.56-.59-.59s-.85.38-1.16.35-.54-.22-.57-.67c-.02-.46 0-.3-.1-.54-.12-.24-.57-.8-.15-.93.43-.14 1.33.08 1.42-.08.08-.16-.48-.65-.85-.83-.37-.19-.96-.51-.65-.78.31-.26.62-.37.79-.61s.37-.91.74-.7c.36.21.87 1.26 1.16 1.18.28-.08.3-.83.25-1.15-.06-.32 0-.88.28-.83s.51.43.96.46c.45.02 1.13-.11 1.07.21-.05.32-.31.71-.62 1.06-.3.36-.45 1.05-.25 1.5.2.46.71 1.19 1.16 1.48s1.3.51 1.84.85c.53.35 1.78 1.34 2.2 1.45s.85.32.85.32.48-.21 1.13-.21 2.14.1 2.71-.14 1.3-.64 1.08-1.15c-.23-.51-1.47-.96-1.36-1.36s.57-.43 1.33-.46c.76-.02 1.8.14 2-.94.2-1.06.26-1.68-.81-1.92-1.08-.24-1.87-.27-2.07-1.04-.2-.78-.39-.97-.17-1.18.23-.21.62-.32 1.41-.37.8-.06 1.7-.06 1.96-.25.25-.18.3-.69.61-.91.31-.21 1.53-.4 1.53-.4s1.46.71 2.8 1.71c1.21.9 2.3 2.23 2.3 2.23'/%3e%3cpath d='M269 243.39s-.8.23-1.1.67c-.37.53-.34 1.07-.34 1.07s.68-.56 1.56-.33c.87.24.96.33 1.33.3s1.27-.35 1.27-.35-.74.86-.65 1.45c.08.58.19.85.17 1.15-.06.72-.6 1.61-.6 1.61s.31-.19 1.05-.35c.73-.16 1.36-.51 1.75-.81.39-.29.9-1.02.9-1.02s-.16 1 0 1.42c.17.44.23 1.67.23 1.67s.47-.42.85-.62c.19-.11.7-.38.9-.7.14-.22.32-1.06.32-1.06s.11.9.39 1.34c.28.42.7 1.74.7 1.74s.29-.86.6-1.21.68-.8.7-1.07c.03-.27-.08-.85-.08-.85l.39.85m-11.41.61s.48-.83.93-1.1c.46-.26 1.08-.74 1.25-.8.16-.05.9-.46.9-.46m.99 5.17s1.09-.55 1.41-.75c.68-.4 1.16-1.12 1.16-1.12'/%3e%3cpath stroke-width='.26' d='M282.57 240.9s-.34-.48-.42-.65c-.09-.15-.23-.48-.23-.48'/%3e%3cpath d='M278.33 257.41s2.04 1.26 1.98 2.31c-.06 1.04-1.13 2.41-1.13 2.41'/%3e%3c/g%3e%3cpath stroke-width='.26' d='M273.05 236.24s-.17-.48-.2-.62c-.03-.13-.12-.29-.12-.29s.88 0 .85.27c-.02.27-.28.27-.34.37-.05.11-.19.27-.19.27z'/%3e%3cpath stroke-width='.05' d='m277.06 234.85-.06-.43s.77 0 1.13.26c.57.4.93 1.02.91 1.05-.1.09-.54-.27-.85-.37 0 0-.23.05-.45.05-.23 0-.34-.11-.37-.21-.03-.12.03-.3.03-.3l-.34-.05z'/%3e%3cpath stroke-width='.26' d='m273.08 240.14.33-.53.34.49-.67.04m.81-.02.4-.53.43.48-.83.05m-.36-3.29.82.29-.74.38-.08-.67m.99.27.73.18-.59.46-.14-.64'/%3e%3cpath fill='%23db4446' stroke-width='.39' d='M261.88 236.08s.48.34.85.4c.37.05.76.05.82.05.05 0 .17-.54.11-.91-.2-1.2-1.3-1.47-1.3-1.47s.33.73.17 1.07c-.23.48-.65.86-.65.86zm-2.29 1.04s-.43-.77-1.33-.67c-.9.11-1.5.81-1.5.81s1-.03 1.25.13c.37.24.48.86.48.86s.54-.32.71-.54c.16-.21.39-.59.39-.59zm-1.1 3.13s-.77.11-1.19.59c-.43.49-.36 1.4-.36 1.4s.5-.54.95-.54c.46 0 1.16.16 1.16.16s-.22-.56-.22-.8-.34-.81-.34-.81zm2.57 10.12s-.42-.45-1.16-.32c-.74.14-1.22.97-1.22.97s.63-.17 1-.08c.36.08.62.45.62.45s.34-.29.45-.45.31-.57.31-.57zm-.85 2.97s-.62-.1-1.16.33c-.53.43-.56 1.25-.56 1.25s.51-.43.91-.37c.39.05.87.27.87.27s.08-.51.11-.64c.09-.38-.17-.84-.17-.84zm1.45 2.74s-.05.79.33 1.28c.4.51 1.13.59 1.13.59s-.24-.53-.28-.8c-.06-.4.34-.75.34-.75s-.37-.38-.73-.38c-.37 0-.79.06-.79.06zm7.34 7.04s-.51-.64-1.21-.62c-.71.03-1.45.69-1.45.69s.88-.07 1.11.22c.23.3.45.67.45.67s.4-.21.57-.35c.17-.13.53-.61.53-.61zm-2.17 2.81s-.93-.14-1.39.35c-.45.48-.42 1.36-.42 1.36s.56-.61 1.07-.56 1.08.32 1.08.32-.09-.53-.15-.78c-.05-.24-.19-.69-.19-.69zm2.01 2.97s-.46.64-.12 1.15 1.05.75 1.05.75-.26-.37-.14-.8c.09-.34.67-.8.67-.8l-1.46-.3zm12.4 1.21s-.81-.19-1.27.08c-.45.26-.82 1.39-.82 1.39s.74-.62 1.28-.54c.53.08.93.3.93.3s.08-.46.02-.78c-.03-.19-.14-.45-.14-.45zm.4 2.99s-.62.64-.4 1.18c.23.54.62 1.1.62 1.1s-.02-.8.23-1.02c.37-.32 1.05-.37 1.05-.37s-.54-.48-.71-.54c-.17-.05-.79-.35-.79-.35zm3.11.94s-.31.78.28 1.28c.59.52 1.11.57 1.11.57s-.46-.81-.32-1.23c.15-.45.54-.72.54-.72s-.74-.25-.85-.22c-.11.02-.76.32-.76.32z'/%3e%3cg fill='%23c8b100' stroke-width='.26'%3e%3cpath d='m282.88 232.71-.29.02c-.01.03-.14.24-.26.35-.26.25-.65.28-.86.07a.486.486 0 0 1-.14-.41c-.17.09-.35.09-.51-.01-.26-.15-.32-.5-.14-.79.03-.06.06-.14.11-.18l-.02-.32-.35.08-.1.19c-.22.25-.54.31-.7.17a.526.526 0 0 1-.13-.27c0 .01-.09.09-.17.11-.54.13-.75-1.05-.77-1.35l-.17.25s.16.7.08 1.3c-.08.59-.29 1.19-.29 1.19.74.19 1.86.8 2.97 1.65s1.98 1.78 2.34 2.42c0 0 .58-.32 1.18-.51s1.36-.2 1.36-.2l.22-.21c-.32.05-1.58.1-1.56-.43 0-.08.07-.18.08-.18a.697.697 0 0 1-.3-.06c-.18-.13-.18-.43.02-.69l.18-.13.01-.34-.34.05c-.03.04-.11.09-.15.13-.27.23-.65.25-.86.03a.416.416 0 0 1-.11-.46.58.58 0 0 1-.45-.05c-.26-.15-.31-.52-.11-.8.09-.14.28-.31.31-.32l-.07-.3h-.01z'/%3e%3cpath fill='%23000' stroke-width='.05' d='M280.63 233.4c.05-.07.15-.06.23 0s.1.16.06.21c-.05.06-.15.06-.24-.01-.07-.05-.1-.15-.05-.2zm.95.79-.33-.25c-.06-.04-.07-.12-.04-.16.04-.04.12-.04.18 0l.33.26.33.25c.05.04.08.12.04.16s-.12.04-.18 0l-.33-.26m-1.74-1.19-.26-.15c-.07-.04-.1-.12-.07-.17s.11-.06.17-.02l.26.16.26.15c.06.03.09.11.07.16-.03.05-.11.06-.17.02l-.26-.15m-1.04-.71c.05-.06.16-.06.24 0 .08.07.1.16.05.22-.05.05-.15.05-.23-.01s-.1-.15-.06-.21zm3.83 2.63c.05-.05.03-.14-.05-.21-.08-.06-.19-.06-.24 0-.04.05-.02.15.06.21s.18.06.23 0zm.57.66.22.21c.05.05.13.07.18.03.04-.04.04-.11-.01-.16l-.21-.21-.22-.21c-.05-.05-.14-.07-.18-.03-.05.03-.04.11.01.16l.21.21m.95.81c.05-.06.03-.15-.05-.21-.08-.07-.18-.07-.23-.01s-.03.15.05.22c.08.05.18.06.23 0z'/%3e%3cpath d='m281.4 230.36-.59.01-.11.87.06.14.15-.01.76-.51-.27-.5'/%3e%3cpath d='m281.4 230.36-.59.01-.11.87.06.14.15-.01.76-.51-.27-.5'/%3e%3cpath d='m279.8 230.84-.02.54.92.12.15-.07-.02-.15-.53-.71-.5.27'/%3e%3cpath d='m281.7 231.92-.49.27-.54-.71-.01-.15.14-.06.93.11-.03.54'/%3e%3cpath d='M280.51 231.25c.08-.13.26-.17.39-.09.14.07.18.24.1.37s-.26.17-.39.09a.26.26 0 0 1-.1-.37zm-2.15-.9c-.02.01-.13-.46-.26-.71-.08-.19-.39-.43-.39-.43.03-.05.42-.19.87.09.38.31-.03.87-.03.87s-.09.14-.19.18z'/%3e%3cpath d='m279.39 230.66-.42.37-.68-.6.06-.08.03-.15.92-.07.09.53'/%3e%3cpath d='M278.24 230.29c.05-.15.18-.23.28-.2.11.04.15.18.1.33s-.18.23-.29.2c-.11-.04-.15-.18-.09-.33zm5.43 1.48-.59-.06-.25.85.05.14.15.01.83-.41-.19-.53'/%3e%3cpath d='m282.01 232.03-.1.54.9.23.15-.04.01-.14-.43-.79-.53.2'/%3e%3cpath d='m283.73 233.36-.53.2-.42-.78.01-.15.15-.03.89.23-.1.53'/%3e%3cpath d='M282.65 232.54c.1-.12.28-.13.4-.04.13.09.15.26.05.38s-.28.13-.41.04a.26.26 0 0 1-.04-.38zm2.99 1.07.11.55-.87.3-.16-.04-.01-.14.36-.81.57.14'/%3e%3cpath d='m285.49 235.2-.56.13-.31-.83.04-.15.15-.02.85.35-.17.52'/%3e%3cpath d='m283.97 233.66-.18.52.85.34.16-.02.03-.14-.3-.83-.56.13'/%3e%3cpath d='M284.91 234.63c.12-.11.12-.28.02-.39a.318.318 0 0 0-.41-.02c-.11.11-.12.28-.01.39.1.11.29.12.4.02zm1.38 1.8c0 .01.5.03.79.09.2.04.52.27.52.27.06-.04.12-.42-.28-.79-.39-.28-.88.22-.88.22s-.12.12-.15.21z'/%3e%3cpath d='m285.75 235.54-.29.46.76.51.09-.08.13-.04-.12-.88-.57.03'/%3e%3cpath d='M286.37 236.53c.14-.07.21-.22.15-.31s-.22-.1-.36-.02-.2.22-.14.31c.05.09.21.1.35.02z'/%3e%3c/g%3e%3cg stroke-width='.61'%3e%3cellipse cx='250.43' cy='281.01' fill='%23ad1519' rx='16.26' ry='18.3'/%3e%3cellipse cx='250.44' cy='280.97' fill='%23005bbf' rx='11.44' ry='13.42'/%3e%3cg id='f' fill='%23c8b100' stroke-width='.34'%3e%3cpath stroke-linejoin='round' d='M245.03 271.74s-1.35 1.48-1.35 2.86c0 1.39.57 2.54.57 2.54-.21-.55-.76-.94-1.41-.94-.83 0-1.5.63-1.5 1.42 0 .22.14.58.24.77l.49.99c.16-.37.54-.57.98-.57.59 0 1.08.45 1.08 1.01 0 .09-.01.17-.04.25l-1.22.01v1.03h1.09l-.81 1.61 1.07-.42.81.91.84-.91 1.07.42-.8-1.61h1.08v-1.03l-1.22-.01c-.02-.08-.02-.16-.02-.25 0-.56.47-1.01 1.06-1.01.44 0 .82.2.98.57l.49-.99c.1-.19.24-.55.24-.77 0-.79-.67-1.42-1.49-1.42-.66 0-1.21.39-1.41.94 0 0 .57-1.15.57-2.54 0-1.38-1.39-2.86-1.39-2.86z'/%3e%3cpath d='M242.87 281.11h4.36v-1.03h-4.36v1.03z'/%3e%3c/g%3e%3cuse xlink:href='%23f' x='10.63'/%3e%3cuse xlink:href='%23f' x='5.31' y='9.14'/%3e%3c/g%3e%3c/g%3e%3c/g%3e%3c/svg%3e)
Universitat Autònoma de Barcelona
Vall d'Hebron Hospital Universitari
Vall d'Hebron Institut de Recerca
Centre d'Esclerosi Múltiple de Catalunya
Hospital Universitario 12 De Octubre
John Wiley & Sons (United States)
Hudson Institute
Instituto de Salud Carlos III
Spanish Multiple Sclerosis Network
Hospital Clínico San Carlos