Introduction:The significance of PDA and indications for treatment of VLBW infants has recently been questioned.Methods: Clinical and eccocardiographic variables were studied in 86 VLBW infants before (D-1) and after (D2, D4, D7) the day (D0) of pharmacologic or surgical treatment for PDA.Results: Compared to D-1, infants given indomethacin or ibuprofen had an increase in both systolic (Ps, p < 0.005) and diastolic (Pd, p < 0.001) blood pressure on D4 compared to D-1), but needed more oxygen (FiO 2 , p < 0001).In infants undergoing surgical ligation an increase in Pd (p < 0.05) and FiO 2 (p < 0.001) was also seen as well as increased need for high frequency ventilation (p = 0.04).Ductal diameter was significantly reduced on D2 (p < 0.001) and D4 (p = 0.047), but peak ductal blood flow or left atrium to aorta width (La/Ao-ratio) did not change.Although only 14.3% of infants treated with indomethacin or ibuprofen had a closed duct evaluated by eccocardiography on D7, only 51.4% needed additional treatment courses.Conclusions: Treatment for PDA improves blood pressure but worsens pulmonary function, particularly after surgery.A significant reduction in ductal size does not improve other eccocardiographic variables.The associations between eccocardiographic findings and clinical symptoms in VLBW infants with PDA need further investigations.
Abstract M-dwarf stars provide us with an ideal opportunity to study nearby small planets. The HUnting for M Dwarf Rocky planets Using MAROON-X (HUMDRUM) survey uses the MAROON-X spectrograph, which is ideally suited to studying these stars, to measure precise masses of a volume-limited (<30 pc) sample of transiting M-dwarf planets. TOI-1450 is a nearby (22.5 pc) binary system containing a M3 dwarf with a roughly 3000 K companion. Its primary star, TOI-1450A, was identified by the Transiting Exoplanet Survey Satellite (TESS) to have a 2.04 days transit signal, and is included in the HUMDRUM sample. In this paper, we present MAROON-X radial velocities (RVs) which confirm the planetary nature of this signal and measure its mass at nearly 10% precision. The 2.04 days planet, TOI-1450A b, has R b = 1.13 ± 0.04 R ⊕ and M b = 1.26 ± 0.13 M ⊕ . It is the second-lowest-mass transiting planet with a high-precision RV mass measurement. With this mass and radius, the planet’s mean density is compatible with an Earth-like composition. Given its short orbital period and slightly sub-Earth density, it may be amenable to JWST follow-up to test whether the planet has retained an atmosphere despite extreme heating from the nearby star. We also discover a nontransiting planet in the system with a period of 5.07 days and a Msinic=1.53±0.18M⊕ . We also find a 2.01 days signal present in the systems’s TESS photometry that likely corresponds to the rotation period of TOI-1450A’s binary companion, TOI-1450B. TOI-1450A, meanwhile, appears to have a rotation period of approximately 40 days, which is in line with our expectations for a mid-M dwarf.
We have implemented upgrades to the University of Wyoming's Red Buttes Observatory (RBO) to allow remote and autonomous operations using the 0.6 m telescope. Detailed descriptions of hardware and software components provide sufficient information to guide upgrading similarly designed telescopes. We also give a thorough description of the automated and remote operation modes with intent to inform the construction of routines elsewhere. Because the upgrades were largely driven by the intent to perform exoplanet transit photometry, we discuss how this science informed the automation process. A sample exoplanet transit observation serves to demonstrate RBO's capability to perform precision photometry. The successful upgrades have equipped a legacy observatory for a new generation of automated and rapid-response observations.
We present an updated characterization of the TOI-1685 planetary system, which consists of a P$_{\rm{b}}$ = 0.69\,day USP super-Earth planet orbiting a nearby ($d$ = 37.6\,pc) M2.5V star (TIC 28900646, 2MASS J04342248+4302148). This planet was previously featured in two contemporaneous discovery papers, but the best-fit planet mass, radius, and bulk density values were discrepant allowing it to be interpreted either as a hot, bare rock or a 50\% H$_{2}$O / 50\% MgSiO$_{3}$ water world. TOI-1685 b will be observed in three independent JWST cycle two programs, two of which assume the planet is a water world while the third assumes that it is a hot rocky planet. Here we include a refined stellar classification with a focus on addressing the host star's metallicity, an updated planet radius measurement that includes two sectors of TESS data and multi-color photometry from a variety of ground-based facilities, and a more accurate dynamical mass measurement from a combined CARMENES, IRD, and MAROON-X radial velocity data set. We find that the star is very metal-rich ([Fe/H] $\simeq$ +0.3) and that the planet is systematically smaller, lower mass, and higher density than initially reported, with new best-fit parameters of \Rpl = 1.468 $^{+0.050}_{-0.051}$ \Rearth\ and \Mpl = 3.03$^{+0.33}_{-0.32}$ \Mearth. These results fall in between the previously derived values and suggest that TOI-1685 b is a hot, rocky, planet with an Earth-like density (\Rhopl = 5.3 $\pm$ 0.8 g cm$^{-3}$, or 0.96 \rhoearth), high equilibrium temperature (T$_{\rm{eq}}$ = 1062 $\pm$ 27 K) and negligible volatiles, rather than a water world.