Hicks Jj

Hospital de Especialidades

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Co-Authors

Nieves Pedrón

Mexican Social Security Institute

Gil Recasens Me

Fisher Ge

C Vilar-Rojas

Mexican Social Security Institute

Gómez Meléndez Mr

Hicks Jn

University of Alabama at Birmingham

de Lourdes Collado M

Durán Reyes G

Hospital de Especialidades

L Calzada

Mexican Social Security Institute

Pascoe Lira D

Hospital de Especialidades

Cooperative Institutions

Mexican Social Security Institute

Hospital de Especialidades

Centro Medico Nacional Siglo XXI

Centro Médico Nacional La Raza

Instituto Nacional de Enfermedades Respiratorias

Universidad Nacional Autónoma de México

Secretaria de Salud

Universidad Autónoma del Estado de México

Stanford University

Universidad Autónoma Metropolitana

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[Structural and metabolic changes of the fertile spermatozoid. I. Maturation and capacitation].

PubMed (1975)

Hicks Jj Nieves Pedrón

Capacitation

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Citations (0)

[New concepts in relation to implantation. IV. Function of the cervical mucus and the endometrial fluid].

PubMed (1979)

Hicks Jj Collado Mde L

Cervical mucus

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[The presence and function of polyamines in the male reproductive system].

PubMed (1987)

José D. Méndez Hicks Jj

Male reproductive system

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Ultrastructural changes in the endometrium of rabbit induced by spermatozoa.

PubMed (1984)

Amador González-Angulo Luís Alberto Blázquez Collado Hicks Jj

Experiments were undertaken to investigate whether ultrastructural changes could be visualized in the endometrial epithelial linings brought about by the presence of spermatozoa. Female rabbits were inseminated with intact spermatozoa in one uterine horn, and the other horn was injected with inactive (dead) spermatozoa, which served as the control. Ruthenium red was used to enhance contrast of glycoproteins of epithelial plasma membranes. There was a decrease in the number and height of microvilli of epithelial cells in those horns injected with intact spermatozoa along with a decrease of ruthenium red deposits. In contrast, microvilli were numerous in those horns injected with inactive spermatozoa, and ruthenium red deposits also were numerous. This marker was not seen between neighboring epithelial cells in any of the injected horns. Control virgin animals, however, disclosed ruthenium red deposits in luminal plasma membranes and along the junctional complexes of epithelial cells. Intact spermatozoa could modify the synthesis or turnover of glycoproteins of outer coats owing to a possible cell-to-cell interaction between spermatozoa and endometrium. The lack of ruthenium red deposits in junctional complexes in the injected animals and their presence in the virgin control rabbits suggest the opening of communicating channels in the two former groups due possibly to the PMSG priming not present in the virgin control animals.

Ruthenium red

Uterine horns

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Citations (1)

[Teratologic effects of benzodiazepines].

PubMed (1991)

Hernández Alvarez La Márquez Orozco Márquez Orozco A Hicks Jj

Benzodiazepines are drugs that belong to the group of minor tranquilizers. They derive from the 1-4, benzodiazepine common nucleus that was obtained by chemical synthesis and act upon the GABA receptors increasing their affinity, thus providing them with their tranquilizing, miorelaxing, and anticonvulsant properties. Due to these characteristics they have been used in a wide variety of disorders accompanied by anxiety, hyperexitability, convulsions, and muscular hypertony, as well as during pregnancy and labor. Before using them in pregnant women, the physician should consider the conditions of the product "in uterus" since, according to experimental evidences, benzodiazepines could interfere with embryonary development, mainly with those involved in central nervous system mechanisms causing tissular alterations, retardment in cellular differentiation, and behavioral disturbances. Besides, since the fetus has lower excretion rate than that of the mother, drug concentrations are greater than the therapeutic ones and fetal tolerance to the compound, administered during the last trimester, is reduced, originating abstinence or intoxication syndromes in the newborn. It is concluded that more research is needed to evaluate all the aftereffects caused by using these drugs during pregnancy.

Anticonvulsant drugs

Abstinence Syndrome

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Citations (1)

[Prenatal diagnosis using chorionic villi].

PubMed (1991)

Vega Hernández Me Hicks Jj J González-Angulo

Chorionic villus sampling (CVS) has a promising future about early detection of fetal abnormalities. It has the potential to become a major tool in the prenatal diagnosis and therapy of genetic disorders. Villus samples can be analyzed by means of cytogenetic, biochemical or molecular technics. Information available at present indicates fetal loss rate should be in the same proportion than amniocentesis. CVS appears to be a reasonably safe and reliable method of prenatal diagnosis in the first trimester of pregnancy. This procedure is setting as fast as it is possible like an excellent alternative to amniocentesis.

Chorionic villus sampling

Amniocentesis

Chorionic villi

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Lactate and pyruvate utilization by the spermatozoa of infertile human males.

PubMed (1978)

Nieves Pedrón Juan Manuel Llopis Giner Hicks Jj

In studying the metabolic pathway of lactate and pyruvate in human spermatozoa from fertile and infertile subjects, pyruvate 1-C14 and lactate 1-C14 were used as substrates in a radiorespirometry system. Spermatozoa from patients with 20 +/- 2.0/10(6) spz/ml and decreased motility (group B) showed a more active decarboxylation of both pyruvate 1-C14 and lactate 1-C14 with a higher production of lactate C14, oxaloacetate, citrate, and isocitrate than those from fertile normal subjects (group A). Spermatozoa from fertile patients with normal counts but low motility (35 +/- 2.0% +++ motility) showed a similar rate of decarboxtlation of pyruvate 1-C14 but a greater rate of decarboxylation of lactate 1-C14 than those from fertile subjects. The low utilization of pyruvate by the spermatozoa from group C infertile patients, with intermediate counts and motility could be explained by a metabolic failure similar to that produced by some inhibitors of the respiratory chain. We do not have an explanation for the metabolic behavior observed in spermatozoa from group B patients, and further research on this point is desirable.

Decarboxylation

Gluconeogenesis

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Citations (5)

[Role of nitric oxide in the reproductive function in mammals].

PubMed (1995)

Villalpando Ramos G Guzmán-Grenfell Am Hicks Jj

NO, is a physiologic messenger involved in many cellular functions widely research at present time. The purpose of this review, is to emphasize the No contribution at reproduction level one aspect more recently on study, a field where it remains yet, many questions to ask.

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An analysis of 435 endoscopic examinations from the bronchoscopic service of the Medical College of Alabama.

Journal of the Medical Association of the State of Alabama (1948)

Fisher Ge Hicks Jj

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[Reproduction biology research at the Mexican Social Security Institute].

PubMed (1983)

Alejandro Reyes-Fuentes Chavarría-Olarte Me R Martínez-Zaguilán Hicks Jj

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