Michele Santoro

Telethon Institute Of Genetics And Medicine

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Giuseppe Di Tullio

Telethon Institute Of Genetics And Medicine

Maria Antonietta De Matteis

Telethon Institute Of Genetics And Medicine

Elena Polishchuk

Telethon Institute Of Genetics And Medicine

Roman Polishchuk

Telethon Institute Of Genetics And Medicine

Rossella Venditti

Telethon Institute Of Genetics And Medicine

Cathal Wilson

Telethon Institute Of Genetics And Medicine

Laura Giaquinto

Telethon Institute Of Genetics And Medicine

Fabrizio Bianchi

Istituto di Fisiologia Clinica

Maria Chiara Masone

Telethon Institute Of Genetics And Medicine

Thiago Moreno L. Souza

Fundação Oswaldo Cruz

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Telethon Institute Of Genetics And Medicine

University of Naples Federico II

Mario Negri Sud Foundation

National Research Council

Federico II University Hospital

University of Padua

National Academies of Sciences, Engineering, and Medicine

Institute of Protein Biochemistry

Istituti di Ricovero e Cura a Carattere Scientifico

Mario Negri Institute for Pharmacological Research

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The activity of Sac1 across ER-TGN contact sites requires the Four-phosphate-AdaPtor-Protein-1

Zenodo (CERN European Organization for Nuclear Research) (2018)

Rossella Venditti Maria Chiara Masone R.L. Rega Giuseppe Di Tullio Michele Santoro

10.5281/zenodo.2527822

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Citations (1)

Isolation and partial characterization of grape aminopeptidase

Journal of Agricultural and Food Chemistry (1981)

Cosimo Pallavicini A. Dal Belin Peruffo Michele Santoro

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsolation and partial characterization of grape aminopeptidaseCosimo Pallavicini, Angelo Dal Belin Peruffo, and Michele SantoroCite this: J. Agric. Food Chem. 1981, 29, 6, 1216–1220Publication Date (Print):November 1, 1981Publication History Published online1 May 2002Published inissue 1 November 1981https://pubs.acs.org/doi/10.1021/jf00108a029https://doi.org/10.1021/jf00108a029research-articleACS PublicationsRequest reuse permissionsArticle Views56Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

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10.1021/jf00108a029

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Cross-Linking Mass Spectrometry to Capture Protein Network Dynamics of Cell Membranome

Methods in molecular biology (2024)

Lucia Santorelli Michele Costanzo Sara Petrosino Michele Santoro Marianna Caterino

Dynamics

10.1007/978-1-0716-4298-6_16

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Additional file 3: Table S3 of Hazardous waste and health impact: a systematic review of the scientific literature

Figshare (2017)

Lucia Fazzo Fabrizio Minichilli Michele Santoro A. Ceccarini Maurella Della Seta

Hazardous waste: acute effects (XLSX 12 kb)

Table (database)

Scientific literature

10.6084/m9.figshare.c.3902503_d3

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Supplementary Material for: Prevalence Estimates of Rare Congenital Anomalies by Integrating Two Population-Based Registries in Tuscany, Italy

Figshare (2017)

Alessio Coi Michele Santoro Anna Pierini Sonia Marrucci F. Pieroni

Background/Aims: Population-based registries play a key role in the epidemiological surveillance of congenital anomalies (CAs). This study is aimed at improving the epidemiological surveillance and providing prevalence estimates of rare CAs using the Registry of Rare Diseases as an added data source to the Registry of Congenital Anomalies. Methods: Cases of diagnosed rare CAs (2006-2013) were extracted from the Tuscany Registry of Rare Diseases and the Tuscany Registry of Congenital Anomalies in order to set up an integrated dataset. Prevalence (per 100,000 births; 95% confidence interval) was calculated for each rare CA. Results: Overall, 56 rare CAs were analyzed including 656 cases, of whom 121 (18.4%) were retrieved from the Registry of Rare Diseases that provided a major contribution for rare CAs for which a prenatal diagnosis is difficult, or for CAs more easily diagnosed in the postneonatal period. After data integration, an increased prevalence estimate was observed in particular for atresia of bile ducts (6.24; 3.57-10.14), tuberous sclerosis (2.34; 0.86-5.10), Kabuki syndrome (1.95; 0.63-4.55), and some monogenic CAs. Conclusions: This study represents an example of integration of registries operating in the field of rare diseases. Providing the accurate prevalence of rare CAs is a key point to improving surveillance, supporting public health policies, and planning healthcare.

10.6084/m9.figshare.5510245

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The TRAPP complex mediates secretion arrest induced by stress granule assembly

The EMBO Journal (2019)

Francesca Zappa Cathal Wilson Giuseppe Di Tullio Michele Santoro Piero Pucci

10.15252/embj.2019101704

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Citations (27)

Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi

Nature (2013)

Giovanni D’Angelo Takefumi Uemura Chia‐Chen Chuang Elena Polishchuk Michele Santoro

Vesicular Transport Proteins

Transport protein

Cell plate

10.1038/nature12423

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Citations (149)

Cytosolic phospholipase A2ε drives recycling in the clathrin-independent endocytic route

Journal of Cell Science (2014)

Mariagrazia Capestrano Stefania Mariggiò Giuseppe Perinetti Anastasia V. Egorova Simona Iacobacci

Previous studies have demonstrated that membrane tubule-mediated transport events in biosynthetic and endocytic routes require phospholipase A2 (PLA2) activity. Here, we show that cytosolic phospholipase A2ε (cPLA2ε, also known as PLA2G4E) is targeted to the membrane compartments of the clathrin-independent endocytic route through a C-terminal stretch of positively charged amino acids, which allows the enzyme to interact with phosphoinositide lipids [especially PI(4,5)P2] that are enriched in clathrin-independent endosomes. Ablation of cPLA2ε suppressed the formation of tubular elements that carry internalized clathrin-independent cargoes, such as MHC-I, CD147 and CD55, back to the cell surface and, therefore, caused their intracellular retention. The ability of cPLA2ε to support recycling through tubule formation relies on the catalytic activity of the enzyme, because the inactive cPLA2ε(S420A) mutant was not able to recover either tubule growth or transport from clathrin-independent endosomes. Taken together, our findings indicate that cPLA2ε is a new important regulator of trafficking processes within the clathrin-independent endocytic and recycling route. The affinity of cPLA2ε for this pathway supports a new hypothesis that different PLA2 enzymes use selective targeting mechanisms to regulate tubule formation locally during specific trafficking steps in the secretory and/or endocytic systems.

10.1242/jcs.136598

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Citations (30)

Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide

Nature (2007)

Giovanni D’Angelo Elena Polishchuk Giuseppe Di Tullio Michele Santoro Antonella Di Campli

Glycosphingolipid

Pleckstrin homology domain

Vesicular Transport Proteins

Sphingolipid

10.1038/nature06097

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