E. Yu. Kovalchuk

Saint-Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine

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i-10 index

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Document Type

Co-Authors

АС

А. С. Повзун

Saint-Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine

ВА

В. А. Костенко

Saint-Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine

E. V. Shchemeleva

Saint-Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine

Mazurov Vi

North-Western State Medical University named after I.I. Mechnikov

АВ

А. В. Рысев

Saint-Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine

K. A. Povzun

Saint-Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine

Alexandr V. Risev

Saint-Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine

ОВ

Ольга Валентиновна Алексеенко

Saint-Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine

ВВ

В. В. Сорока

Saint-Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine

O. V. Alexeenko

Saint-Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine

Cooperative Institutions

Saint-Petersburg I. I. Dzhanelidze Research Institute of Emergency Medicine

Research Institute of Emergency Care

North-Western State Medical University named after I.I. Mechnikov

Petrozavodsk State University

Duke Medical Center

Clinical Research Institute

Russian Academy of Sciences

Institute of Oriental Studies

Peoples' Friendship University of Russia

Perm State University

Author Statistics

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Citation

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Assessment of the efficacy of mexidol in the combination with hyperbaric oxygen in acute ischemic stroke

S S Korsakov Journal of Neurology and Psychiatry (2018)

N S Kulai E. Yu. Kovalchuk

To study the efficacy of mexidol in the combination with hyperbaric oxygenation (HBO) in comparison with the standard HBO sessions in patients with acute ischemic stroke. One hundred and twelve patients were examined. In the main group, 48 patients underwent HBO and received treatment with mexidol. The control group consisted of 64 people who underwent the standard HBO sessions only. The use of combination therapy (HBO+mexidol) leads to the significantly more rapid normalization of acute phase indices which are correlated with neurological deficit reduction.Эффективность применения мексидола в сочетании с гипербарической оксигенацией (ГБО) изучали в сравнении со стандартными сеансами ГБО у больных в острейшем периоде ишемического инсульта (ИИ). Были обследованы 112 пациентов с ИИ. В основную группу вошли 48 больных, которым проводилась ГБО в сочетании с внутривенным введением мексидола. Контрольную группу составили 64 пациента, которым проводились стандартные сеансы ГБО без введения мексидола. Установили, что использование комбинированной терапии (ГБО+мексидол) приводит к достоверно более быстрой нормализации показателей острой фазы заболевания, коррелирующей со степенью снижения неврологического дефицита.

Neurological deficit

Hyperbaric oxygenation

10.17116/jnevro20181183269-72

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Citations (5)

Case of lactacidosis in acute kidney damage and metformin therapy

HERALD of North-Western State Medical University named after I I Mechnikov (2021)

Ольга Валентиновна Алексеенко E. Yu. Kovalchuk Alexandr V. Risev Anastasiya M. Sergeeva Alexey V. Lapickiy

Тhe article provides a clinical observation of the development of a rare pathological condition of lactic acidosis in a patient with acute kidney injury while taking metformin and confirms the need for timely determination of blood lactate. Тhe clinical case confirms that the development of lactic acidosis in a patient with diabetes mellitus may have a mixed etiology and be associated not only with the use of metformin, but also with the presence of tissue hypoxia, exposure to an infectious process, and impaired renal function. The development of lactic acidosis is associated with an increase in secretion and / or a decrease in the rate of excretion of lactate, which is expressed in a state of metabolic acidosis and severe cardiovascular insufficiency. The development of lactic acidosis is most often associated with the presence of renal and / or hepatic insufficiency, diabetes mellitus, lung pathology, macromicrocirculation disorders, and hemoglobin function defects, the treatment with biguanide drugs (metformin). Diagnosis of lactic acidosis is based on the data from a biochemical blood test and electrolyte parameters the concentration of blood plasma lactate, the study of acid-base state of the blood and anion gap.

Lactic acidosis

Biguanide

10.17816/mechnikov81407

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The representation of postinfarction myocardial rupture

HERALD of North-Western State Medical University named after I I Mechnikov (2018)

E. Yu. Kovalchuk А. В. Рысев Yu. A. Kovalchuk O. V. Alexeenko

The article presents a literature review of the modern conception of postinfarction rupture of the myocardium and predictors of its development.

Representation

10.17816/mechnikov20181015-10

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Citations (1)

NEW OPPORTUNITIES FOR EARLY PROGNOSIS OF POSTINFARCTION MYOCARDIAL RUPTURE

E. Yu. Kovalchuk А. С. Повзун

家禽企业最重要的社会和劳工指标是确保充分利用劳动力资源和提高劳动生产率，为员工创造正常的工作条件，提高报酬水平，实现员工的适当经济增长和生活质量。本文对"提高劳动生产率和支持就业"区域计划的结果进行了分析，并对彼尔姆地区的家禽业提供了支持。关键词：劳动生产率，家禽养殖，区域计划，增长储备

10.34660/inf.2020.63.19.001

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Acute coronary syndrome in a patient with transient ischemic attack: challenges of antithrombotic therapy (a clinical case)

Neurology neuropsychiatry Psychosomatics (2019)

E. Yu. Kovalchuk А. С. Повзун В. А. Костенко Agnese Brega

The paper presents experience with antithrombotic therapy in a critically ill patient with acute coronary syndrome and transient ischemic attack. It characterizes problems in triple antithrombotic therapy in a very ill patient with comorbidity. The paper demonstrates an incremental approach to choosing therapy according to the clinical picture of disease, an assessment of risk factors for ischemic and hemorrhagic complications over time, which is very important in the routine practice of a physician. It also shows how, based on existing recommendations, the optimal anticoagulant is chosen as part of triple and double antithrombotic therapy in terms of its potential risks and possible complications.

Anticoagulant Therapy

10.14412/2074-2711-2019-4-156-159

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Prevalence of аcute articular syndrome. Literature review and own data

EMERGENCY MEDICAL CARE (2022)

А. С. Повзун Mazurov Vi E. V. Shchemeleva K. A. Povzun E. Yu. Kovalchuk

The study of the occurrence of articular syndrome in general, and acute articular syndrome (AAS) in particular, is an important medical and social task, the solution of which makes it possible to determine the amount of necessary forces and means for the organization of medical care for these patients. Since 2008, the authors have been studying the features of diagnosis and treatment of patients with AAS, for the first time in the Russian Federation on the basis of the St. Petersburg Research Institute of Emergency Medicine named after I. I. Dzhanelidze introduced the concept of providing medical care to patients with AAS into clinical practice. The study of data on the prevalence of articular syndrome allows us to outline ways to optimize diagnostic and therapeutic algorithms, reducing the time of diagnosis of diseases and optimizing the duration of the inpatient stage of treatment.

Medical care

10.24884/2072-6716-2022-23-4-61-73

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Nutritive correction of insulin resistance and hyperglycemia in acute myocardial infarction

HERALD of North-Western State Medical University named after I I Mechnikov (2018)

Ольга Валентиновна Алексеенко Alexandr V. Risev V. M. Luft В. А. Костенко E. Yu. Kovalchuk

Currently the emergency medicine turned on the wide use of the special enteral nutritional cocktails like “Diabetes” to manage different types of hyperglycemia and insulin resistance under various acute disorders. The prognostic value of GH and the effectiveness of its early control in a given target range were studied using these EPS as the only source of nutrition for patients in the acute phase of the course of the first arisen myocardial infarction

Enteral administration

10.17816/mechnikov201810120-26

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Rheumatic diseases as a reason for emergency hospitalization

Rheumatology Science and Practice (2023)

А. С. Повзун Mazurov Vi E. V. Shchemeleva K. A. Povzun E. Yu. Kovalchuk

The study of pain in the projection of joints occurrence is an important medical and social task, the solution of which makes it possible to determine the amount of necessary forces and means for the organization of medical care for these patients. For the first time in Russian Federation on the basis of Saint-Petersburg Research Institute of Emergency Care named after I.I. Dzhanelidze the concept of providing medical care to patients with pain in the projection of joints was introduced into clinical practice. The study of the prevalence of pain in the projection of joints data, places and roles of rheumatological diseases (RD) allows to outline ways to optimize diagnostic and therapeutic algorithms, reducing the time of diseases diagnosis and optimizing the inpatient stage of treatment duration. An increase in the proportion of patients referred to the outpatient stage allows rational use of specialized beds in the hospital and gives a significant economic effect for the healthcare system. RD are the second most common cause of pain in the projection of joints. Its average percentage of patients referred for hospitalization was 2.69% of the total number of patients in the Saint-Petersburg Research Institute of Emergency Care named after I.I. Dzhanelidze. The structure of the incoming flow of patients with pain in the projection of joints was analyzed, the nosological structure of patients with RD was evaluated. Osteoarthritis, rheumatoid arthritis and gouty arthritis are the leading causes of pain in the projection of joints.

10.47360/1995-4484-2023-356-360

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POST-INFARCTION CARDIAC RUPTURE

HERALD of North-Western State Medical University named after I I Mechnikov (2015)

E. Yu. Kovalchuk А. В. Рысев

The field of post-infarction myocardial ruptures is still a nearly blind spot of cardiology; there are many facts about it which are ambiguous and simply too vague. For example, the dispersion in frequency rate is quite self-explanatory: from 0 to 30 or even 35 per cent. A number of clinical studies concerning the 30 days mortality due to acute myocardial infarctions just ignores myocardial ruptures as being the cause of death. This probably comes from a certain confusion as the post-infarction myocardial ruptures and the cardiogenic shock have almost similar manifestations. However pathologists participating in those not so numerous clinical studies concerning the 30 days mortality due to acute MIs presume that the real frequency rate of myocardial ruptures is much higher and stands at 20 to 36 per cent among all cases.

Confusion

Cardiac Rupture

10.17816/mechnikov20157397-101

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Current clinical and epidemiological portrait of a patient with acute myocardial infarction (by the data of the regional vascular center)

The Scientific Notes of the Pavlov University (2015)

E. Yu. Kovalchuk В. В. Сорока

Epidemiological and clinical presentation of acute myocardial infarction based upon the data collected in Regional Vascular Centre of Saint-Petersburg Scientific Research Institute of Emergency Care n. a. I. I. Dzhanelidze in 2009-2012 years. In the article, 4697 cases have been analyzed. Specific features of epidemiology and clinical presentation of acute myocardial infarction at the present stage have been considered.

Presentation (obstetrics)

Saint petersburg

10.24884/1607-4181-2015-22-2-56-60

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Citations (1)