Maureen Shields

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Kenneth J. Schaffer

Advocate Lutheran General Hospital

Amy Stewart

University of St Andrews

Jennifer Dela‐Pena

Advocate Lutheran General Hospital

Morgan Anderson

Advocate Lutheran General Hospital

Kellie Arensman

Advocate Lutheran General Hospital

Erik LaChance

Advocate Illinois Masonic Medical Center

Jenna Sutton

Rosalind Franklin University of Medicine and Science

Michelle Kitsis

University of Illinois Chicago

John V. White

Advocate Lutheran General Hospital

Rovi Origenes

Advocate Lutheran General Hospital

Cooperative Institutions

Advocate Lutheran General Hospital

Advocate South Suburban Hospital

Advocate Trinity Hospital

Swedish Covenant Hospital

Advocate Christ Medical Center

Advocate Illinois Masonic Medical Center

Advocate Good Samaritan Hospital

Advocate Health Care

Rosalind Franklin University of Medicine and Science

University of Iowa

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Fluoroquinolone versus Beta-Lactam Oral Step-Down Therapy for Uncomplicated Streptococcal Bloodstream Infections

Antimicrobial Agents and Chemotherapy (2020)

Kellie Arensman Maureen Shields Maya Beganovic Jessica L. Miller Erik LaChance

Fluoroquinolones (FQs) are often preferred as oral step-down therapy for bloodstream infections (BSIs) due to favorable pharmacokinetic parameters; however, they are also associated with serious adverse events. The objective of this study was to compare clinical outcomes for patients who received an oral FQ versus an oral beta-lactam (BL) as step-down therapy for uncomplicated streptococcal BSIs. This multicenter, retrospective cohort study analyzed adult patients who completed therapy with an oral FQ or BL with at least one blood culture positive for a Streptococcus species from 1 January 2014 to 30 June 2019.

Bacteremia

Beta-lactam

Combination therapy

10.1128/aac.01515-20

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Citations (23)

Deep Vein Thrombosis Screening with Risk Assessment Profile and Trauma Patients: A Quality Evaluation

Journal of the American College of Surgeons (2021)

Amy Stewart Kenneth J. Schaffer Rovi Origenes Maureen Shields

Quality Assessment

10.1016/j.jamcollsurg.2021.08.581

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