Appendiceal neoplasms have a diverse histological classification, the commonest type being neuro-endocrine neoplasm and accounting for 60% of all primary appendiceal malignancies. Others include colonic-type adenocarcinoma; mucinous neoplasm, and goblet cell carcinoma. This report describes a unique case of three different histological subtypes of appendiceal malignancy within a single specimen. A 65-year-old female presented with symptoms concerning of GI malignancy and underwent computerised tomography pneumocolon showing an abnormally enhancing appendix concerning for an appendiceal tumour. After multidisciplinary team discussion the patient underwent an open right hemicolectomy. Post-operative histological analysis showed complete resection of three distinct tumour subgroups within the specimen: a neuroendocrine tumour; a well-differentiated adenocarcinoma, and a low-grade appendiceal mucinous neoplasm. This report describes, to our knowledge, the first documented case of three separate histological malignancies in a single appendix. Appendiceal malignancy is rare and there are less than 10 cases pertaining to the appendix in the literature: all describing dual neuroendocrine tumours and appendiceal mucinous neoplasms. The case also highlights a limitation of colonoscopy in the diagnosis of colorectal malignancy, specifically for appendiceal tumours, and caution must be taken in discharging patients after a negative colonoscopy. A multi-disciplinary approach is of utmost importance in managing these patients. This is a rare case of 3 morphologically different neoplasms contained within one appendix and demonstrates the importance of an MDT approach to management of such cases. It also highlights the limitation of colonoscopy in diagnosis of appendiceal malignancy.
In qualitative research, interviews are utilized in data collection, especially in the Medical field. This literature review analyzes the advantages and disadvantages for in-person and telephone methods. The PubMed and PubMedCentral ® databases were searched and yielded five relevant articles in the locale of medicine for review. Telephone interviews are found to be shorter, cost less, are reported to display less interviewer bias, and are seen to report less information while in-person interviews require more training, are conducive to physical tests, and are harder to schedule. In-person and telephone interviews are both accurate within acceptable error for qualitative research studies. In cases where a majority of the sample may not have access to telephones, the extra cost of the in-person interview is justified to develop rapport and increased accuracy to add validity to the study. Telephone interviews may be the preferred method unless the in-person interview provides benefits to the research that outweigh the additional costs. This study was a sub-study for a larger project with an overall goal of understanding the dynamics of health communication in grandfamilies and how these dynamics may differ by race.
Abstract This study analyzes the effectiveness of ultrasound-guided hydrodissection (HD) perineural as a treatment for radial tunnel syndrome (RTS). A literature search was performed along with retrospective analysis of local cases to assess outcomes and safety of this procedure. In the case series, surgical candidates, defined as cases with over 80% but temporary relief after diagnostic injection, were treated with ultrasound-guided HD. Of 22 patients who received ultrasound-guided diagnostic injections, 11 proceeded to HD. All HD patients experienced complete and lasting symptom resolution for a minimum of 2 years, and none required surgery. Thorough literature review provided seven studies, which fulfilled inclusion criteria. Sixty-one patients are represented in the literature. All studies reported significant benefit to pain symptoms with HD of radial nerve, with five specifying over 90% improvement. No adverse effects from HD were noted in any study. Ultrasound-guided HD of the radial tunnel has potential to be a surgery sparing treatment for RTS.
Obesity has been on the rise globally and more people are now clinically obese than ever before in the US. This issue has a significant impact on both health and cost to healthcare systems. Bariatric surgery is efficacious in treatment of obesity but only in late stages of the disease, and there is a requirement for less invasive techniques/devices to treat obesity at earlier stages. Currently a number of these are either in clinical trials or have recently been approved by the Food and Drug Administration for weight loss. This review aims to give an overview of the newer technologies and techniques being used in bariatric surgery. It will also give a glimpse into future methods and those that have fallen short in recent times.
In scientific investigation, data is required to test a hypothe sis. In qualitative human research, one method of gathering non-numerical information is performed via interview. The choice of method (telephone versus in-person) is an important study design element. The data collection method can have ram ifications of response rates and data fidelity along with resource (personnel, supplies, and monetary) utilization. However, the rationale for the choice of data collection method is not always described in qualitative research articles. In-person interviews usually are considered the gold standard in qualitative research in regard to validity and quality of response in the field of health care. This literature review adds to general knowledge in the field by analyzing the validity of telephone interviews in qual itative research to determine the effectiveness of this alternate method. We also examined the current literature to compare telephone and in-person interviews for qualitative data collection from human research subjects. Although this literature review determined that the in-person and telephone interview are equally effective in gathering valid data, further research on the methods in diverse populations is needed to clarify the generalizability of the finding. METHODS
'%3e%3cpath fill='%23012169' d='M0 0v30h60V0z'/%3e%3cpath stroke='%23fff' stroke-width='6' d='m0 0 60 30m0-30L0 30'/%3e%3cpath stroke='%23C8102E' stroke-width='4' d='m0 0 60 30m0-30L0 30' clip-path='url(%23b)'/%3e%3cpath stroke='%23fff' stroke-width='10' d='M30 0v30M0 15h60'/%3e%3cpath stroke='%23C8102E' stroke-width='6' d='M30 0v30M0 15h60'/%3e%3c/g%3e%3c/svg%3e)
