P. Sabín

Hospital General Universitario Gregorio Marañón

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Co-Authors

Mariano Provencio

Hospital Universitario Puerta de Hierro Majadahonda

Marta Llanos

Hospital Universitario de Canarias

José Gómez‐Codina

Hospital Universitari i Politècnic La Fe

David Berlana

Universitat de Barcelona

R. Burgos

Vall d'Hebron Hospital Universitari

C. Puiggròs

Vall d'Hebron Hospital Universitari

Antonio Rueda

Instituto de Investigación Biomédica de Málaga

A. Rueda

Industrial University of Santander

L. Chicharro

Vall d'Hebron Hospital Universitari

Cristina Quero

Hospital Costa del Sol

Cooperative Institutions

Vall d'Hebron Hospital Universitari

Hospital Universitario Puerta de Hierro Majadahonda

Universitat Autònoma de Barcelona

Instituto de Salud Carlos III

Hospital General Universitario Gregorio Marañón

Universitat de Barcelona

Universidad Autónoma de Madrid

Hospital Universitario Ramón y Cajal

Centro de Investigación Biomédica en Red de Cáncer

Vall d'Hebron Institut de Recerca

Author Statistics

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Identification of Molecular Risk Score in Advanced Hodgkin Lymphoma: Integrating Tumor and Microenvironment Signatures.

Blood (2009)

Beatriz Sánchez‐Espiridión Carlos Montalbán Mónica García‐Cosío José García‐Laraña Javier Menárguez

Clinical Significance

10.1182/blood.v114.22.3660.3660

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Citations (0)

Effects on hemodynamics and gas exchange of omega-3 fatty acid-enriched lipid emulsion in acute respiratory distress syndrome (ARDS): a prospective, randomized, double-blind, parallel group study

Lipids in Health and Disease (2008)

Joan Sabater‐Riera Joan Ramón Masclans Judit Sacanell Pilar Chacón P. Sabín

Abstract Introduction We investigated the effects on hemodynamics and gas exchange of a lipid emulsion enriched with omega-3 fatty acids in patients with ARDS. Methods The design was a prospective, randomized, double-blind, parallel group study in our Intensive Medicine Department of Vall d'Hebron University Hospital (Barcelona-Spain). We studied 16 consecutive patients with ARDS and intolerance to enteral nutrition (14 men and 2 women; mean age: 58 ± 13 years; APACHE II score: 17.8 ± 2.3; Lung Injury Score: 3.1 ± 0.5; baseline PaO 2 /FiO 2 ratio: 149 ± 40). Patients were randomized into 2 groups: Group A (n = 8) received the study emulsion Lipoplus ® 20%, B.Braun Medical (50% MCT, 40% LCT, 10% ω-3); Group B (n = 8) received the control emulsion Intralipid ® Fresenius Kabi (100% LCT). Lipid emulsions were administered during 12 h at a dose of 0.12 g/kg/h. Measurements of the main hemodynamic and gas exchange parameters were made at baseline (immediately before administration of the lipid emulsions), every hour during the lipid infusion, at the end of administration, and six hours after the end of administration lipid infusion. Results No statistically significant changes were observed in the different hemodynamic values analyzed. Likewise, the gas exchange parameters did not show statistically significant differences during the study. No adverse effect attributable to the lipid emulsions was seen in the patients analyzed. Conclusion The lipid emulsion enriched with omega-3 fatty acids was safe and well tolerated in short-term administration to patients with ARDS. It did not cause any significant changes in hemodynamic and gas exchange parameters. Trial registration ISRCTN63673813

Clinical nutrition

Lipidology

10.1186/1476-511x-7-39

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Citations (41)

Combined Therapy with Rituximab Plus Cyclophosphamide/Vincristine/Prednisone for Sjogren’s Syndrome-Associated B-Cell Non-Hodgkin’s Lymphoma

Clinical Reviews in Allergy & Immunology (2007)

Javier Carbone Ricardo Pérez-Fernández Andrés J. Muñoz Martín P. Sabín Luis Carreño

Immunophenotyping

10.1007/s12016-007-8025-2

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Citations (9)

Stability of Ranitidine Hydrochloride in Total Nutrient Admixtures

American Journal of Health-System Pharmacy (1988)

Santiago M. Cano José Bruno Montoro Ronsano Carmen Pastor Leonor Pou P. Sabín

The stability of ranitidine hydrochloride in total nutrient admixtures (TNAs) containing 5% intravenous fat emulsion was studied. A TNA containing lipids and glucose was prepared aseptically in three ethylene-vinyl acetate bags. Ranitidine hydrochloride 100 mg and 200 mg was added to two of the bags to yield concentrations of 50 μ/mL and 100 μ/mL, respectively. The third bag served as a control. At 0, 12, 24, 48, and 72 hours, the ranitidine content was measured by high-performance liquid chromatography, the pH of the admixtures was determined, and the bags were visually inspected for signs of color changes, creaming, or precipitates. Particle-size distribution was measured at 72 hours and compared with that in the control bag at time zero. No appreciable changes in pH occurred over 72 hours, and no visual changes were observed. At concentrations of 50 and 100 μ/mL of admixture, ranitidine hydrochloride activity declined approximately 80% during the study period. Approximately 10% of the initial concentration was lost in 12 hours. In both cases, there was no variation in particle-size distribution compared with that in the control bag at time zero. Ranitidine hydrochloride appears to be stable for up to 12 hours at room temperature in the admixtures studied, and the lipid emulsion apparently was not altered during this period by ranitidine.

Creaming

Hydrochloride

10.1093/ajhp/45.5.1100

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Citations (22)

PP173-MON IMPACT OF ADMINISTERING FISH OIL ON OUTCOMES OF SURGICAL PATIENTS RECEIVING PARENTERAL NUTRITION

Clinical Nutrition Supplements (2012)

David Berlana M.J. De Dios P. Sabín L. Chicharro Javier Martínez

10.1016/s1744-1161(12)70512-4

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Citations (0)

Are there any significant variations in the clinical or histological presentation of lymphoid pathologies over the course of time in Spain?

Clinical & Translational Oncology (2012)

Mariano Provencio P. Sabín José Codina Antonio Rueda Marta Llanos

Presentation (obstetrics)

Course (navigation)

10.1007/s12094-012-0813-3

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Citations (4)

A molecular risk score based on 4 functional pathways for advanced classical Hodgkin lymphoma

Blood (2010)

Beatriz Sánchez‐Espiridión Carlos Montalbán Angel Alfonso Velarde López Javier Menárguez P. Sabín

10.1182/blood-2010-02-270009

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Citations (51)

Chapter-03 A Discussion on Diabetic Ulcer Foot

Jaypee Brothers Medical Publishers (P) Ltd. eBooks (2009)

P. Sabín

Diabetic foot ulcer

10.5005/jp/books/10878_3

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Análisis de costes de los sistemas de nutrición parental: bolsa tricompartimental versus manual

David Berlana P. Sabín Vicente Gimeno‐Ballester Rosa Romero‐Jiménez Amalia Zapata-Rojas

Background Parenteral nutrition (PN) is a costly technology used widely to provide nutrition to patients who have an inaccessible or non-functioning intestine. Two all-in-one systems currently being used are customized formulations and three-compartment bags. Objective To provide a systematic cost comparison of the two all-in-one PN systems: individualized (made from nutrient solutions) versus commercialized (made from three-compartment bag), both prepared in hospital pharmacies. Setting This study was conducted in three public Spanish hospitals. Method We conducted a cost-minimization study to analyze prospectively the total cost of PN bags, accounting for all of the processes involved in preparing and delivering PN bags (cost of manpower, nutrition solutions, medical supplies and quality controls) in three different healthcare settings. To compare therapeutic alternatives of equivalent nutritional value, the study was performed for the most frequently employed formulation and similar to commercial preparations. A univariate sensitivity analysis was performed to evaluate the impact of different rates of use of three-compartment PN bag. Results 157 routine acts of PN bag preparation (65 customized and 92 three-compartment) were observed and timed over 9 days. Total costs of the 157 PN bags were included in the study. Mean costs of customized bags were higher than three-compartment bags, 51.16±5.63€ versus 39.69±3.00€ respectively (p<0.01). Manpower costs were responsible for the majority of the differences found (70%). The time to complete an adult bag for the hospital compounded system was a mean of 25.9 minutes longer than the three-compartment system. In scenarios using a three-compartment system for 30%, 70% and 90% of PN provision, a cost savings of 4.3%, 10.1% and 12.9% respectively could be achieved. Greatest rates of changing from customized bags (70% and 90%), in a hospital with 1,800 PN bags/year, might reduce the annual budget by 9306€ and 11,964.8€, respectively. Meanwhile, in a large facility the savings for 8,000 TPN days would be 64,248€ and 82,605€, respectively. Conclusions Since seeking cost-reduction of effective treatments is needed, the use of three-compartment bags for standard adult PN could lead to cost savings. Our data should be helpful for health care providers to calculate their own cost of administer TPN.

Univariate analysis

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PP436 ZINCEMIA IN SEVERE GASTROINTESTINAL PATHOLOGY

Clinical Nutrition Supplements (2010)

L. Chicharro Pilar Chacón P. Sabín Berta Renedo Josep M. Guiu

Gastrointestinal pathology

Gastrointestinal system

10.1016/s1744-1161(10)70511-1

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