Z. Crane

Amide

Depsipeptide

Combretastatin

10.1016/j.bmc.2005.04.040

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Citations (14)

CCDC 240442: Experimental Crystal Structure Determination

The Cambridge Structural Database (2004)

Michael J. Hickey David V. Goeddel Z. Crane Yian Shi

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc8266q

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Citations (0)

Exploring structural effects of ketone catalysts on asymmetric epoxidation of olefins

Tetrahedron (2005)

Z. Crane David V. Goeddel Yonghong Gan Yian Shi

Carbonyl group

10.1016/j.tet.2005.03.123

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Citations (21)

Synthesis of Methyl-1-(tert-butoxycarbonylamino)-2-vinylcyclopropanecarboxylate via a Hofmann Rearrangement Utilizing Trichloroisocyanuric Acid as an Oxidant

The Journal of Organic Chemistry (2010)

Z. Crane Paul J. Nichols Tarek Sammakia Peter J. Stengel

A trichloroisocyanuric acid (TCCA) mediated Hofmann rearrangement was utilized to synthesize methyl-1-(tert-butoxycarbonylamino)-2-vinylcyclopropanecarboxylate. A variety of functional groups are tolerated in this reaction including vinyl, cyclopropyl, pyridyl, aryl, benzyl, and nitro groups.

Trichloroisocyanuric acid

10.1021/jo101504e

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Citations (44)

CCDC 278993: Experimental Crystal Structure Determination

The Cambridge Structural Database (2005)

Z. Crane David V. Goeddel Yonghong Gan Yian Shi

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc9c9sq

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Citations (0)

CCDC 278994: Experimental Crystal Structure Determination

The Cambridge Structural Database (2005)

Z. Crane David V. Goeddel Yonghong Gan Yian Shi

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc9c9tr

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Highly enantioselective epoxidation of styrenes: Implication of an electronic effect on the competition between spiro and planar transition states

Proceedings of the National Academy of Sciences (2004)

Matthew S. Hickey David V. Goeddel Z. Crane Yian Shi

Asymmetric epoxidation of various styrenes using carbocyclic oxazolidinone-containing ketone 3 has been investigated. High enantioselectivity (89–93% enantiomeric excess) has been attained for this challenging class of alkenes. Mechanistic studies show that substituents on the ketone catalyst can have electronic influences on secondary orbital interactions, which affects the competition between spiro and planar transition states and, ultimately, enantioselectivity. The results described herein not only reveal the potential of chiral dioxirane catalyzed asymmetric epoxidation as a viable entry into this important class of olefins but also further enhance the understanding of the mechanistic aspects of chiral ketone-catalyzed asymmetric epoxidation.

Dioxirane

Transition state

10.1073/pnas.0307548101

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Citations (56)

Dolastatin 11 Connects Two Long-pitch Strands in F-actin to Stabilize Microfilaments

Journal of Molecular Biology (2003)

Toshiro Oda Z. Crane Christopher W. Dicus Bilal A. Sufi Robert B. Bates

Phalloidin

10.1016/s0022-2836(03)00306-1

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Citations (30)

CCDC 240441: Experimental Crystal Structure Determination

The Cambridge Structural Database (2004)

Michael J. Hickey David V. Goeddel Z. Crane Yian Shi

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc8265p

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Citations (0)

CCDC 278996: Experimental Crystal Structure Determination

The Cambridge Structural Database (2005)

Z. Crane David V. Goeddel Yonghong Gan Yian Shi

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc9c9wt

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