PURPOSE: To report on the occurrence of monosymptomatic bilateral posterior lenticonus in 7 members of the same family and discuss the diagnoses and methods of management. SETTING: Eye Clinic, Cantonal Hospital, Lucerne, Switzerland. METHODS: Two sisters were found to suffer from bilateral posterior lenticonus. The 3 sons of the elder sister and the 2 daughters of the younger sister all presented with bilateral posterior lenticonus. A cataract operation or a clear lens extraction with intraocular lens implantation was performed in 4 of the 7 patients. RESULTS: The disorder was found to be inherited and to follow a pattern of autosomal dominance. Visual acuity improved to 20/20 in all operated eyes. CONCLUSION: This may be the largest group in 1 family presenting with bilateral posterior lenticonus described to date. Treatment of posterior lenticonus, if necessary, can be successfully managed as an ordinary cataract.
Impaired hemodynamics in neonatal sepsis increase the mortality.
Objective
Studying the changes in hemodynamics and peripheral perfusion in premature infants with suspected sepsis and comparing them with stable matched controls.
Methods
Left (LVO) and right ventricular output (RVO), and superior vena cava (SVC) flow were measured using echocardiography in newborn infants with suspected sepsis after DOL 7. Measurements were repeated 3 times q 24 h and when antibiotics were discontinued. Anterior cerebral artery RI and oxygenation of the brain and the kidney were measured by near infrared spectroscopy (NIRS). Vital parameters were monitored. Controls were studied once; matched with cases for GA, BW, and postnatal age.
Results
Twelve preterm infants (GA 26.8 ± 2.5 wks; BW 843 ± 225 g) were studied at postnatal age 13.5 (7- 60) days and compared to 12 stable matched controls. Four cases had a positive blood culture, six had an elevated CrP, and 2 had an elevated IL8 only. LVO showed an increase over time reaching a maximum of 404 ± 104 ml/kg/min on the 3rd measurement point (p = 0.046 compared to the 1st measurement) and was higher compared to controls (p = 0.04). SVC flow showed a trend towards increase over time. The control group had a higher SVC flow at the initial measurement (p = 0.05). No significant change in RVO, NIRS, Doppler parameters, and in blood pressure over time or compared to controls, although five cases required circulatory support either by volume therapy, catecholamines or both.
Conclusions
Suspected sepsis was associated with haemodynamic changes which may have implications for clinical management.
In this paper we propose a novel in-car realtime streaming multimedia architecture. This architecture is based on the Ethernet protocol combined with a single audio/video compression format that is valid throughout the car. Audio/video content deviating from the in-car format is transcoded by a central transcoding unit for delivery in the car. In this context, we compare three different transcoding approaches which differ in their design and performance. In the first scheme a cascaded transcoding unit consisting of a full decoder and a full encoder is studied. In the second approach, the transcoder reuses the motion information extracted from the incoming video stream. The motion information is either adopted without modification or serves for the initialization of a low-complexity motion search process in the encoder. The third transcoder investigated in this work reuses both motion information as well as the encoded residual data (DCT coefficients). All three trancoders have been implemented in an in-car communication prototype. We investigate the performance of the three transcoders by means of their complexity and their rate-distortion (RD) performance. From our experimental results we conclude that the transcoder which reuses both motion vectors and DCT coefficients shows the best trade-off between complexity and RD performance.
ABSTRACT— A case of chronic non‐A, non‐B (NANB) hepatitis in a 17‐year‐old male is reported. The special feature was microtubular aggregates described so far only in experimental NANB hepatitis in chimpanzees. Additional characteristics were a severe chronic active hepatitis with confluent necrosis in a late stage, multinucleated hepatocytic giant cells and nuclear aggregates of 20–27 nm viruslike particles.
<H4>BACKGROUND AND OBJECTIVE</H4> <P> To evaluate the results of combined vitrectomies and intraocular lens implantations in cases of proliferative diabetic retinopathy. </P> <H4>PATIENTS AND METHODS</H4> <P> Data from procedures on 117 eyes (91 patients) undergoing combined pars plana vitrectomy, phacoemulsification, and intraocular lens implantation for the complications of proliferative diabetic retinopathy were analyzed retrospectively. Follow-up ranged from 8 to 64 months (median = 25 months). </P> <H4>RESULTS</H4> <P>Retinal tears were the most frequent intraoperative problems (19%). Limited postoperative fibrin formation occurred in 22% of eyes. Within 6 months, 7% developed glaucoma and 2% showed new anterior segment rubeosis. Overall, 10% underwent secondary surgical procedures as follows: lavage for hemorrhage (n = 3), silicone oil exchange after 7 days for focal rebleeding (n = 1), silicone oil surgery for retinal detachment after gas resorption (n = 1), and lavage for late vitreous hemorrhage (7 to 13 months) (n = 4). Half of the secondary procedures were necessitated within 3 months of the original surgery. </P> <H4>CONCLUSIONS</H4> <P> Combined surgery in proliferative diabetic retinopathy is safe and effective. It should be considered when lens opacities are either present or likely to develop soon. </P> <P>[<CITE>Ophthalmic Surg Lasers Imaging</CITE> 2006;37:468-474.] </P> <H4>AUTHORS</H4> <P>From the Department of Ophthalmology, Kantonsspital, Luzern, Switzerland. </P> <P>Accepted for publication February 10, 2006. </P> <P>Presented in part at the Frankfurt-Marfurt Retina Meeting, June 14, 2003. </P> <P>Address reprint requests to Peter Senn, MD, Augenklinik Kantonsspital, Spitalstr., CH - 6000 Luzern 16, Switzerland. </P>