İG

İsmail Güzelmansur

Zübeyde Hanim Maternity Hospital

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Hanifi Bayaroğulları

Mustafa Kemal University

ÇA

Çağatay Andıç

Başkent University

Vefik Arıca

Istanbul Eye Hospital

Murat Gedikoğlu

Başkent University

İŞ

İbrahim Şilfeler

Ankara Yıldırım Beyazıt University

H. Evren Eker

İstanbul Başakşehir Çam ve Sakura Şehir Hastanesi

Sibel Hakverdi

Mustafa Kemal University

Levent Oğuzkurt

Koç University

Seçil Arıca

Sağlık Bilimleri Üniversitesi

Naim Ceylan

Ege University

Cooperative Institutions

Mustafa Kemal University

Sağlık Bilimleri Üniversitesi

Başkent University

Ege University

Cukurova University

Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi

Sivas State Hospital

Ankara Atatürk Göğüs Hastalıkları Ve Göğüs Cerrahisi Eğitim Ve Araştırma Hastanesi

Trakya University

Ministry of Health

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Serum ischemia modified albumin levels in pregnancies with neural tube defects.

PubMed (2012)

İsmail Güzelmansur Yusuf Üstün Yaprak Engin Üstün Özlem Görüroğlu Öztürk Halıl Yaman

To evaluate ischemia-modified albumin (IMA) in women who had been pregnant with a child suffering from neural tube defect.Samples from 50 women who had been pregnant with an affected child (25 spina bifida, 25 anencephaly) and 25 controls matched for age, gestational age, and body mass index were studied. We measured serum IMA by enzyme-linked immunosorbent assay.Serum IMA was significantly higher in the study group compared to normal pregnancies (p < 0.05). The area under the receiver operating curve was 0.858 for IMA (95% CI, 0.769-0.947), whereas the optimal threshold value of IMA to discriminate between affected children and controls was 0.409 (sensitivity 88%, specificity 80%). The risk for increased IMA in mothers who have conceived a fetus with neural tube defect is 24.5 times higher than in the control group (rr = 24.5, 6.9-86.9, 95% CI) (p = 0.001).This study indicates that serum IMA in women who have conceived a fetus with neural tube defect is significantly higher than that in normal pregnant women.

Anencephaly

Neural tube defect

Ischemia-modified albumin

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Citations (2)

Latent polyglandular autoimmune syndrome type 2 case diagnosed during a shock manifestation

Gynecological Endocrinology (2016)

Eren Gürkan Berrin Çetinarslan İsmail Güzelmansur Beyza Kocabaş

There are many types of polyglandular autoimmune syndrome (PAS). PAS type 2 is the most common type among adults. For PAS type 2 (PAS-2) diagnosis, detection of Addison's disease with autoimmune thyroid disease and/or type 1 diabetes mellitus are required. Premature ovarian insufficiency, pernicious anemia, vitiligo, alopecia, myasthenia gravis, celiac disease and autoimmune diabetes insipidus may be comorbidities of this condition. Contrary to the common belief, latent PAS is more common than the manifest forms. Here, we present a PAS-2 case diagnosed via adrenal crisis. At the time of diagnosis, the case was observed to have thyroid, adrenal and ovarian involvement. Therefore, PAS-2 and possible immunologic disorders were discussed.

Vitiligo

pernicious anemia

Adrenocortical Insufficiency

10.3109/09513590.2015.1137096

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Citations (4)

Comparison of Sedoanalgesia Versus Ultrasound-Guided Supraclavicular Brachial Plexus Block for the Prevention of the Pain During Endovascular Treatment of Dysfunctional Hemodialysis Fistulas

CardioVascular and Interventional Radiology (2019)

Murat Gedikoğlu Çağatay Andıç İsmail Güzelmansur H. Evren Eker Çağatay Bölgen

10.1007/s00270-019-02293-8

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Citations (9)

Endovenous laser ablation and sclerotherapy for incompetent vein of Giacomini

Phlebology The Journal of Venous Disease (2013)

İsmail Güzelmansur Levent Oğuzkurt Nihal Koca Çağatay Andıç Murat Gedikoğlu

To retrospectively evaluate the feasibility and effectiveness of endovenous laser ablation or ultrasound-guided foam sclerotherapy for Giacomini vein insufficiency. This is the largest cohort of patients treated for Giacomini vein insufficiency with endovenous laser ablation or ultrasound-guided foam sclerotherapy.Over a three-year period, 23 females and nine males (age range, 19-67 years) treated for Giacomini vein insufficiency with or without saphenous vein insufficiency were retrospectively reviewed. Diagnosis of venous insufficiency was made by color Doppler ultrasonography. Symptomatic insufficiency of the Giacomini vein or the saphenous veins was treated with endovenous laser ablation. Ultrasound-guided foam sclerotherapy was used for tortuous incompetent Giacomini veins. The venous disease was categorized according to the clinical, etiological, anatomical, and pathological classification, and clinical severity was graded with the venous clinical severity score. Follow-up included clinical examination and color Doppler ultrasonography.Thirty-nine limbs in 32 patients were treated (25 endovenous laser ablation and seven ultrasound-guided foam sclerotherapy). All procedures were technically successful. One patient in the ultrasound-guided foam sclerotherapy group had a recurrence with successful repeated treatment. Recurrence was not seen in the endovenous laser ablation group. No complications were observed. All patients had resolution and improvement in 100% of their symptoms at 12 months of follow-up.Giacomini vein insufficiency is mostly seen with insufficiency of the great saphenous vein and can be effectively treated with endovenous laser ablation or ultrasound-guided foam sclerotherapy.

Great saphenous vein

Chronic Venous Insufficiency

Laser Ablation

Doppler ultrasound

10.1177/0268355513496552

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Citations (8)

Prenatal diagnosis of Goldenhar syndrome with unusual features by 3D ultrasonography.

PubMed (2013)

İsmail Güzelmansur Gülay Ceylaner Serdar Ceylaner Naim Ceylan Turgay Daplan

Oculoauriculo-vertebral spectrum, or Goldenhar syndrome, is characterized by varying degrees of prevalently unilateral underdevelopment of craniofacial structures (orbit, ear, and mandible) and spinal anomalies. We report a patient with unusual features diagnosed prenatally by 3D ultrasonography at 21 weeks' gestation without a family history. An early diagnosis was suggested by observation of a maxillary cleft-plate, multiple vertebral segmentation defects and hypoplastic thumb. Postnatal evaluation also revealed ambiguous genitalia and club feet in addition to the prenatally and postnatally diagnosed classical Goldenhar syndrome features like hemifacial microsomia, preauricular and facial skin tags, coloboma of eyelids, epibulbar dermoid.

Goldenhar syndrome

Hemifacial microsomia

Coloboma

Orbit (dynamics)

Dysostosis

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Citations (11)

Akciğer gelişimsel anomalili olgularımız

Tülin Durgun Yetim Hanifi Bayaroğulları İsmail Güzelmansur Vefik Arıca İbrahim Şilfeler

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CT imaging of superior semicircular canal dehiscence: Added value of reformatted images

Acta Oto-Laryngologica (2010)

Naim Ceylan Selen Bayraktaroğlu Hüdaver Alper Recep Savaş Cem Bilgen

Superior semicircular canal dehiscence (SSCD) syndrome may present with various symptoms. CT scans previously interpreted as normal may show SSCD, especially if special reconstructions tailored for superior canal evaluation are added.The purpose of this study was to investigate prevalence of SSCD, its length and its correlation with symptoms in patients who had previously undergone temporal bone CT examination that was reported normal and to demonstrate the importance of reformatted images in the diagnosis of SSCD.We retrospectively reviewed 108 patients who had undergone temporal bone CT examination for various symptoms and were reported as normal. High-resolution temporal bone CT imaging was performed with 1 mm slice thickness in the transverse plane. Each of the superior semicircular canals was evaluated in the plane of Pöschl and Stenver reformatted images together with axial images.Ninety-three patients were included in the study. Nineteen patients with semicircular canal dehiscence were detected. The mean age of the study group was 45 years. Radiologic evidence of SSCD occurred in 23 of 186 temporal bones with a radiologic prevalence of 12%. The most common symptoms in dehiscent patients were vertigo, hearing loss and tinnitus. Defect lengths varied between 1 mm and 6.5 mm.

10.3109/00016481003602108

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Citations (51)

Fetal Cervical Neuroblastoma: Prenatal Diagnosis

Case Reports in Medicine (2011)

İsmail Güzelmansur Hatice Tatar Aksoy Sibel Hakverdi Mustafa Seven Uǧur Dilmen

Neuroblastoma is the most frequent extracranial solid tumor in childhood, but it is seldom diagnosed prenatally. It usually presented with adrenal masses. Presentation of other localization is extremely rare. We report a case of cervical neuroblastoma identified at 20 weeks of gestational age. This is the third case diagnosed antenatally on neck region in the literature. Additionally, it is the first case that extended to the brain. We also discussed the literature for cervical neuroblastoma detected prenatally.

Presentation (obstetrics)

Solid tumor

Case presentation

10.1155/2011/529749

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Citations (9)

Fetal MR Ürografi ile Posterior Üretral Valvin Prenatal Tanısı

DergiPark (Istanbul University) (2012)

İsmail Güzelmansur Hanifi Bayaroğulları Vefik Arıca Orhan Oyar

Posterior uretral valv (PUV) prenatal donemde, erkek fetuslerde en sik izlenen alt uriner sistem obstruksiyon nedenidir. Obstruksiyona bagli olarak proksimal uretrada anahtar deligi gorunumu, mesanede distansiyon, vezikoureteral refluye (VUR) sekonder, ureterlerde ve pelvikaliksiyel sistemde dilatasyon izlenir. Obstruksiyonun derecesi ve suresi bobrekteki hasari ve prognozu belirler. PUV prenatal donemdeki teshisinde, ultrasonografi (US) ilk ve en yaygin kullanilan goruntuleme yontemidir. Anne ve fetusten kaynaklanan nedenlerden dolayi manyetik rezonans goruntu- leme (MRG) tamamlayici ve yardimci yontem olarak tercih edilebilir. Olgumuz MRG’in prenatal PUV teshisine katkisini gostermektedir.

10.18229/ktd.45942

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Evaluation of fetal autopsy findings in the hatay region: 274 cases

Turkish Journal of Pathology (2012)

Sibel Hakverdi İsmail Güzelmansur Arif Güngören Serhat Toprak Mehmet Yaldız

The aim of this study was to present the incidence of fetal anomalies in our region of Hatay, Turkey in order to determine the efficiency of prenatal diagnosis through fetal autopsy, and to compare our statistical data with other national and international studies.This study was conducted on 274 fetuses from terminated pregnancies due to abnormal prenatal findings and intrauterine deaths from 2005 to September 2010. Fetuses were evaluated through postmortem examination, external measurements, X-rays, Magnetic Resonance Images, Multislice Computerized Tomography and photographs. The autopsy was completed by the histological examination of each organ.Autopsy was conducted on 274 fetuses. A fetal anomaly was detected in 160 (58.39%) cases. The central nervous system contained the most frequent structural defects (79 cases, 49.38%), followed by malformations in the musculoskeletal system in 36 cases (22.5%). The most frequent multiple system anomalies were central nervous system defect and bilateral adrenal agenesis, musculoskeletal system malformations and urinary system defects. Fetal autopsy provided additional findings in 43 cases (26.88%).Fetal autopsy is a very important procedure and an integral part of the general prenatal management. New findings through this method may suggest invaluable data for parents about potential risks in future pregnancies.

10.5146/tjpath.2012.01115

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Citations (11)