Engin Kandıralı

Bağcılar Eğitim ve Araştırma Hastanesi

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Atilla Semerciöz

Bağcılar Eğitim ve Araştırma Hastanesi

Mustafa Zafer Temiz

Bağcılar Eğitim ve Araştırma Hastanesi

AÇ

Aykut Çolakerol

Bağcılar Eğitim ve Araştırma Hastanesi

Ahmet Yaser Müslümanoğlu

Bağcılar Eğitim ve Araştırma Hastanesi

Emrah Yürük

Bağcılar Eğitim ve Araştırma Hastanesi

Murat Tunç

Harran University

Ahmet Tefekli̇

Istanbul Arel University

ÖŞ

Öner Şanlı

Istanbul University

Ahmet Metın

Bolu Abant İzzet Baysal University

ÖÇ

Ömer Çakır

Kings Health Partners

Cooperative Institutions

Sağlık Bilimleri Üniversitesi

Istanbul University

Bağcılar Eğitim ve Araştırma Hastanesi

Bolu Abant İzzet Baysal University

Ministry of Health

University of Health Science

Ankara University

Başkent University

University of Health Sciences

Haydarpaşa Numune Eğitim ve Araştırma Hastanesi

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Serum C-NLR score, a new inflammatory marker, predicts tumor histopathology and oncological outcomes of localized clear cell renal carcinoma after nephrectomy: A single center retrospective analysis

Journal of Surgery and Medicine (2023)

Aykut Çolakerol Mustafa Zafer Temiz Yiğit Can Filtekin Sergen Şahin Ramazan Ömer Yazar

Background/Aim: Several blood and serum-based parameters have been described as prognostic markers of clear cell renal cell carcinoma (ccRCC). But most of these markers have inconsistent results and are not used in routine clinical practice. Therefore, novel potential predictor biomarkers are needed for the management of ccRCC patients in clinical practice. Here, we investigate the predictive value of a novel marker, serum C-NLR score, for pathological characteristics and oncological outcomes of ccRCC. Methods: A total of 162 RCC patients who underwent radical or partial nephrectomy between January 2015 and January 2021 were evaluated in a retrospective cohort study setting. The serum C-NLR score was compared according to the tumor histopathology-associated parameters. The predictive role of those parameters and C-NLR score on the oncological outcomes of ccRCC was also investigated. Results: The median serum C-NLR scores exhibited statistically significant increases in ccRCC patients with pathological necrosis, lymphovascular invasion, and variant differentiation. Among histopathological characteristics, only tumor necrosis and variant differentiation were associated with overall survival (OS) and tumor grade with metastasis-free survival (MFS) (no metastasis detected in grade 1–2 tumors) in Kaplan Meier analyses. Serum C-NLR score was also associated with OS but not MFS. In the univariate analyses, tumor necrosis, variant differentiation, and C-NLR score were associated with OS of localized RCC patients who underwent nephrectomy (HR: 0.29; 95% CI: 0.08–1.01; P=0.04, HR: 6.01; 95% CI: 1.66–21.82; P=0.006 and, HR: 1.21; 95% CI: 0.20–5.16; P=0.04). However, in the multivariate analysis, only variant differentiation and C-NLR score were associated with OS (HR: 1.43; 95% CI: 0.82–2.98; P=0.03 and HR: 1.21; 95% CI: 0.20–5.16; P=0.04). Tumor grade was directly associated with MFS because grade 1–2 tumors did not exhibit any metastasis. Conclusion: Serum C-NLR score was higher in worse histopathological entities. Moreover, it predicts the OS for patients with ccRCC as an independent factor.

Lymphovascular invasion

Histopathology

Single Center

Univariate analysis

Predictive marker

10.28982/josam.7663

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Increased potential for high reactive oxygen species generation in pure sperm from leukocytospermic patients.

Fertility and Sterility (2001)

Ramadan Saleh Rakesh Sharma Engin Kandıralı Essam Nada A.J. Thomas

Semen quality

Interquartile range

Semen Analysis

10.1016/s0015-0282(01)02458-x

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Bladder Dysfunction in Behçet’s Disease

Journal of Academic Research in Medicine (2016)

Murat Dinçer Ömer Çakır O. Fikri Engin Kandıralı

Behcet’s disease (BD) is a systemic vasculitis usually seen in young adults, which affects both venous and arterial vessels of the vascular system. Its etiology is still unknown. The patognomic symptoms are recurrent oral aphtae accompanies with at least two of these; positive pathergy test, skin lesions, recurrent genital ulcers and lesions in the eye. Urogenital involvement usually consists of genital ulcers, urethritis, epididymitis and recurrent cystitis. Bladder involvement is extremely rare and only several cases have been reported. The findings suggest that neurogenic bladder due to neuro-Behcet disease is characterized uro-dynamically by overactive detrusor in storage phase and detrusor sphincter dyssynergia in voiding phase 12. We aimed to present

10.5152/jarem.2016.972

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VAJİNAL EVİSERASYON: KADINDA RADİKAL SİSTEKTOMİ SONRASI GÖRÜLEN NADİR KOMPLİKASYON

Marmara medical journal (2004)

Engin Kandıralı Ahmet Tefekli̇Faruk Özcan

Literaturde, kadin radikal sistektomi serileri artan siklikla bildirilmesine ragmen, gec donem komplikasyonu olarak vajinal eviserasyondan fazla bahsedilmemektedir. Burada, radikal sistektomiden 8 ay sonra olusan vajinal eviserasyon vakasi bildirilmistir. Anahtar Kelimeler:: Radikal sistektomi, Kadin, Vajinal eviserasyon

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Does the Metabolic Syndrome or Its Components Affect the Outcome of Percutaneous Nephrolithotomy?

Journal of Endourology (2007)

Ahmet Tefekli̇Hilal Kurtoğlu Kadir Tepeler Mert Ali Karadağ Engin Kandıralı

Metabolic syndrome is a cluster of cardiovascular disease risk factors. We assessed the impact of these medical disorders on the outcome of percutaneous nephrolithotomy (PCNL).Data from 430 consecutive PCNL procedures were retrospectively reviewed. The presence of serum lipid abnormalities (SLA), hypertension (HT), diabetes (DM), and obesity was investigated. Patients were determined to have the metabolic syndrome according to the definition of the International Diabetes Federation. Success rate, need for auxiliary procedures, and major complication rates of PCNL were analyzed separately for patients with or without DM, SLA, HT, obesity, and the metabolic syndrome, and were compared.SLA, HT, and DM were observed in 123 (28.6%), 108 (25.1%), and 44 (10.2%) patients, respectively. Body mass index was >30 kg/m2 in 74 (17.2%) patients. Metabolic syndrome was diagnosed in 41 (9.5%) patients. An overall success rate of 96.3% for PCNL was achieved. Success rates were not significantly (P > 0.05) influenced by the presence of SLA, HT, DM, obesity, or the metabolic syndrome. Major complications were encountered in 49 (11.4%) patients and were 2.5 to 2.7 times more common in patients with DM, HT, and the metabolic syndrome. In patients with DM, auxiliary treatment alternatives were necessary in 20.5%, while they were indicated in 10.9% of patients without DM (P = 0.046). Presence of the metabolic syndrome was also associated with an increased necessity for auxiliary treatments after PCNL (P = 0.048).Our results indicate that the metabolic syndrome and its components (DM and HT) significantly augment auxiliary treatment and complication rates after PCNL.

Lithotomy position

10.1089/end.2007.0034

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Bladder Stone Secondary to Retained Foley Catheter Balloon in a Woman

Journal of Academic Research in Medicine (2015)

Mustafa Zafer Temiz Murat Dinçer Engin Kandıralı

Foley

Foley catheter

Bladder stones

Balloon catheter

10.5152/jarem.2015.676

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BILATERAL SINGLE SYSTEM URETERAL ECTOPIA DIAGNOSED INCIDENTALLY WITH INFERTILITY

The Journal of Urology (2004)

Öner Şanlı Orhan Ziylan Engin Kandıralı Ateş Kadıoğlu Cavit Ozsoy

No AccessJournal of UrologyAdult Urology: Physiology/Medical Disease/Adrenal1 Sep 2004BILATERAL SINGLE SYSTEM URETERAL ECTOPIA DIAGNOSED INCIDENTALLY WITH INFERTILITY ONER SANLI, ORHAN ZIYLAN, ENGIN KANDIRALI, ATES KADIOGLU, and CAVIT OZSOY ONER SANLIONER SANLI More articles by this author , ORHAN ZIYLANORHAN ZIYLAN More articles by this author , ENGIN KANDIRALIENGIN KANDIRALI More articles by this author , ATES KADIOGLUATES KADIOGLU More articles by this author , and CAVIT OZSOYCAVIT OZSOY More articles by this author View All Author Informationhttps://doi.org/10.1097/01.ju.0000134514.76653.ecAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "BILATERAL SINGLE SYSTEM URETERAL ECTOPIA DIAGNOSED INCIDENTALLY WITH INFERTILITY." The Journal of Urology, 172(3), pp. 1026–1027 References 1 : Single-system ectopic ureters: a review of 12 cases. J Pediatr Surg1992; 27: 491. Google Scholar 2 : Bilateral single ureteral ectopia. Eur Urol1988; 14: 41. Google Scholar 3 : Bilateral single ureteral ectopia: difficulty attaining continence using standard bladder neck repair. J Urol1997; 158: 1933. Link, Google Scholar From the Department of Urology, Istanbul Faculty of Medicine, University of Istanbul, Istanbul, Turkey© 2004 by American Urological Association, Inc.FiguresReferencesRelatedDetails Volume 172Issue 3September 2004Page: 1026-1027 Advertisement Copyright & Permissions© 2004 by American Urological Association, Inc.Keywordshydronephrosisureter abnormalitiesinfertilityMetricsAuthor Information ONER SANLI More articles by this author ORHAN ZIYLAN More articles by this author ENGIN KANDIRALI More articles by this author ATES KADIOGLU More articles by this author CAVIT OZSOY More articles by this author Expand All Advertisement PDF downloadLoading ...

10.1097/01.ju.0000134514.76653.ec

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Re: Singh A et al. Robot-assisted retroperitoneal lymph node dissection: Feasibility and outcome in postchemotherapy residual mass in testicular cancer. Indian J Urol 2017;33:304-9

Indian Journal of Urology (2017)

MustafaZafer Temiz Ömer Çakır Engin Kandıralı Atilla Semerciöz

10.4103/iju.iju_341_17

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MP-13.18 Presence of Neutrophilic Infiltration in the Prostate and its Relationship with Serum PSA Levels in Asymptomatic Patients

Urology (2011)

Ömer Çakır Engin Kandıralı Çetin Boran Erdinc Serın Atilla Semerciöz

Infiltration (HVAC)

Cellular infiltration

10.1016/j.urology.2011.07.317

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Conservative Management of the Duodenal Injury during Percutaneous Nephrostomy Placement: A Few and Far between Complications of the Urological Literature

Case Reports in Urology (2021)

Aykut Çolakerol Mustafa Zafer Temiz Mubarek Bargicho Adem Kamil Özdoğan Fatih Çelebi

Herein, we reported a duodenal perforation case as an intestinal injury during a percutaneous nephrostomy procedure. A 73-year-old woman with bilateral nephrostomy catheters was applied to the emergency service with right flank pain. Early in the day, her bilateral nephrostomy catheters had been changed. On physical examination, she had a defense and rebound at her right quadrant, and costovertebral angle tenderness was also positive. In the contrast-enhanced abdominal computed tomography scan, the right nephrostomy catheter was located in the second part of the duodenum, and the contrast agent did not leak into the peritoneum from the injury area. We decided on conservative management of the case with active surveillance using daily blood tests and physical examinations. The nephrostomy catheter in the duodenum was left to prevent fistula between the duodenum and the skin, and a new one was placed in the right kidney. The broad spectrum antibiotherapy regime was applied, and the patient was followed up closely. The catheter in the duodenum was removed on the 20th day, uneventfully, and the patient was discharged successfully on the 24th day with her permanent bilateral nephrostomy tubes. On the first follow-up, one month later, the patient had no active medical complaint.

Percutaneous nephrostomy

Nephrostomy

10.1155/2021/8221488

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