K. H. Gugel

University of Tübingen

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E. Bayer

Incyte (United States)

Hanspaul Hagenmaier

University of Tübingen

S. Jessipow

University of Tübingen

Klaus D. Haegele

Klinikum St. Georg

H Zähner

University of Tübingen

W. A. Koenig

Universität Hamburg

K. Hägele

Trinity College Dublin

H. ZAEHNER

University of Tübingen

W. A. König

University of Tübingen

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University of Tübingen

ETH Zurich

Novartis (Switzerland)

Universität Hamburg

Klinikum St. Georg

Hormel (United States)

University of Reading

Fondation Jean-Marie Lehn

Hôpital Saint-Antoine

Sorbonne Université

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ChemInform Abstract: STOFFWECHSELPRODUKTE VON MIKROORGANISMEN 98. MITT. PHOSPHINOTHRICIN UND PHOSPHINOTHRICYL‐ALANYL‐ALANIN

Chemischer Informationsdienst (1972)

E. Bayer K. H. Gugel Klaus D. Haegele Hanspaul Hagenmaier S. Jessipow

Abstract Aus Kulturen von Streptomyces viridochromogenes wird das neue Antibioticum (I) isoliert.

10.1002/chin.197214456

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Stoffwechselprodukte von Mikroorganismen. 98. Mitteilung. Phosphinothricin und Phosphinothricyl‐Alanyl‐Alanin

Helvetica Chimica Acta (1972)

E. Bayer K. H. Gugel K. Hägele Hanspaul Hagenmaier S. Jessipow

Abstract From cultures of Streptomyces viridochromogenes a new antibiotic, phosphinothricylalanyl‐alanine, has been isolated. The new amino acid phosphinothricin is 2‐amino‐4‐methyl‐phosphino‐butyric acid, its structure is confirmed by synthesis. The tripeptide is highly active against Gram ‐positive and Gram ‐negative bacteria and against the fungus Botrytis cinerea . Phosphinothricin is an active glutamine synthetase inhibitor.

Tripeptide

10.1002/hlca.19720550126

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Citations (415)