Type 2 diabetes is a serious, expensive and growing public health challenge. NICE guidance recommends diabetes prevention in people at high risk via intensive lifestyle interventions promoting weight loss. There are few robustly evaluated ‘real-world' diabetes prevention programmes in the UK. Immediate evidence on the effectiveness, cost-effectiveness and deliverability of such programmes is needed to inform the proposed UK National Diabetes Prevention Programme.
Aims: To assess whether an existing community-based diabetes prevention programme delivered by voluntary sector providers is effective in modifying diabetes risk factors in adults with “pre-diabetes”.
Background: Type 2 diabetes is a growing public health challenge. NICE guidance recommends diabetes prevention in people at high risk via intensive lifestyle interventions promoting weight loss through diet and physical activity. However, there are few robustly evaluated ‘real-world’ diabetes prevention programmes in the UK.
Methods: ComPoD (www.isrctn.com/ISRCTN70221670) is a randomised, waiting list controlled trial of the LWTC programme conducted across two sites (Devon, West Midlands). Adults with pre-diabetes referred by GPs were randomised to receive LWTC immediately (intervention) or after 6 months (control). The trial supplements a wider parallel before-after service and process evaluation involving all LWTC programme participants. In line with guidance, LWTC comprises 4-6 weekly group sessions followed by regular support contacts and attendance at 5+ additional classes up to 12 months. Changes from baseline to 6 months in objective measures of weight, blood glucose and physical activity, and self-reported diet, health status and psychological well-being were assessed.
Results: Trial recruitment (n=314) was completed in June 2015, with 43% of participants male, a mean (SD) age of 61 (9.87) years, weight of 87.28 (15.14) kg and BMI of 31.83 (4.54) kg/m2. Amongst 191 overweight LWTC participants providing 6-month follow up data for the before-after evaluation by July 2015, there were significant positive changes in weight (1.77kg loss), blood glucose (1.85mmol reduction), healthy eating and depression (all p<0.01).
Conclusions: Initial findings on this innovative, replicable, real-world, voluntary-sector led programme are promising. However, 6-month comparative trial data due early 2016 will provide more robust evidence on programme effectiveness which will be timely in light of the proposed UK National Diabetes Prevention programme.
Funding: Big Lottery (LWTC); NIHR School for Public Health Research (ComPoD).
Type 2 diabetes is a growing public health challenge. NICE guidance recommends diabetes prevention in people at high risk via intensive lifestyle interventions promoting weight loss through diet and physical activity. However, there are few robustly evaluated ‘real-world' diabetes prevention programmes in the UK.