Milan Milovancev

Oregon State University

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Atiya Mansoor

Oregon Health & Science University

Charles Keller

Children's Cancer Therapy Development Institute

Regina Gandour‐Edwards

University of California, Davis

Noah Berlow

Ascent Technology (United States)

Jonathan Noujaim

Hôpital Maisonneuve-Rosemont

Ranadip Pal

Texas Tech University

Tomohide Tsukahara

Sapporo Medical University

Robert G. Maki

Memorial Sloan Kettering Cancer Center

Matthew N. Svalina

University of Colorado Anschutz Medical Campus

Khin Thway

Royal Marsden NHS Foundation Trust

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John Wiley & Sons (United States)

127

Hudson Institute

110

Oregon State University

The Ohio State University

North Carolina State University

University of California, Davis

Colorado State University

University of Georgia

University of Wisconsin–Madison

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Congenital patellar aplasia in a family of cats

Veterinary and Comparative Orthopaedics and Traumatology (2004)

S. Christopher Ralphs Milan Milovancev

Summary A diagnosis of congenital bilateral patellar aplasia was made in two male littermate Siamese cats that presented for abnormal conformation and hind limb gait. Both cats had abnormalities of the femora, tibiae, fibulae, and tali. The owners reported that the cats were able to ambulate adequately in the house and jump onto low-lying objects. Other than signs related to this developmental anomaly, significant abnormal clinical signs were not noted in either cat. According to the owner, none of the other littermates were affected, but the seven year old sire displayed identical clinical signs. Unfortunately, the sire and littermates were not available for examination. Treatment was not pursued for either cat.

Aplasia

Sire

Abnormality

Hindlimb

10.1055/s-0038-1632799

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Citations (3)

A multiplex biomarker approach for the diagnosis of transitional cell carcinoma from canine urine

Analytical Biochemistry (2014)

Shay Bracha Michael J. McNamara Ian Hilgart Milan Milovancev Jan Medlock

Multiplex

Proteome

Diagnostic biomarker

Biomarker Discovery

10.1016/j.ab.2014.03.017

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Citations (18)

EVALUATION OF DIFFERENT COMPUTED TOMOGRAPHY TECHNIQUES AND MYELOGRAPHY FOR THE DIAGNOSIS OF ACUTE CANINE MYELOPATHY

Veterinary Radiology & Ultrasound (2010)

Sophie Dennison Randi Drees Helena Rylander Brian S. Yandell Milan Milovancev

Forty-six dogs with either cervical (C1–C5 or C6–T2) or thoracolumbar (T3–L3) acute myelopathy underwent prospective conventional computed tomography (CT), angiographic CT, myelography, and CT myelography. Findings were confirmed at either surgery or necropsy. Seventy-eight percent of lesions were extradural, 11% were extradural with an intramedullary abnormality, 7% were intramedullary, 2% were intradural–extramedullary, and 2% had nerve root compression without spinal cord compression. Intervertebral disc herniation was the most frequent abnormality regardless of signalment or neurolocalization. Twenty-one of 23 Hansen type I disc extrusions but none of the Hansen type II disc protrusions were mineralized. Two chondrodystrophic dogs had acute myelopathy attributable to extradural hemorrhage and subarachnoid cyst. CT myelography had the highest interobserver agreement, was the most sensitive technique for identification of compression, demonstrating lesions in 8% of dogs interpreted as normal from myelography and enabling localization and lateralization in 8% of lesions incompletely localized on myelography due to concurrent spinal cord swelling. None of the imaging techniques evaluated permitted definitive diagnosis of spinal cord infarction or meningomyelitis but myelography and CT myelography did rule out a surgical lesion in those cases. While conventional CT was adequate for the diagnosis and localization of mineralized Hansen type I disc extrusions in chondrodystrophic breeds, if no lesion was identified, plegia was present due to concurrent extradural compression and spinal cord swelling, or the dog was nonchondrodystrophic, CT myelography was often necessary for correct diagnosis.

Spinal cord compression

10.1111/j.1740-8261.2010.01667.x

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Citations (39)

Issue Information

Veterinary Radiology & Ultrasound (2019)

Hayley Paradise Lorrie Gaschen Mara Wanderer Chin‐Chi Liu Luke Granger

Cover IllustrationFrom Specchi and D'Anjou.Schematic illustration of collateral vascular pathways caused by caudal vena cava obstructions in dogs.Superficial (A), intermediate (B), portal (C), and deep (D) collateral pathways.Caudal vena cava obstruction is depicted in yellow (A-D) and the white arrowheads indicate the collateral pathways (A and C).AV, azygos vein; RECIV, right circumflex iliac vein; LIIV, left internal iliac vein; RGoV, right gonadal vein; LGoV, left gonadal vein; RUrV, right urethral vein; RUtV, right uterine vein; UB&UtVP, urinary bladder and uterine venous plexi; CrMV, cranial mesenteric vein; CdMV, caudal mesenteric vein; RPl, rectal plexi; LV and VPl, lumbar veins and vertebral plexi.

10.1111/vru.12650

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Comparative Pathology of Canine Soft Tissue Sarcomas: Possible Models of Human Non-rhabdomyosarcoma Soft Tissue Sarcomas

Journal of Comparative Pathology (2014)

Milan Milovancev Marlene Hauck Charles Keller Lauren W. Stranahan Atiya Mansoor

Desmin

Myxofibrosarcoma

CD31

Epithelioid sarcoma

Hemangiosarcoma

Spindle cell sarcoma

10.1016/j.jcpa.2014.09.005

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Citations (27)

Additional file 26: of Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma

Figshare (2019)

Noah Berlow Rishi Rikhi Mathew Geltzeiler Jinu Abraham Matthew N. Svalina

Table S12. Phospho Screen data - U23674. (XLSX 657 kb)

10.6084/m9.figshare.8288384

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Citations (0)

Additional file 17: of Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma

Figshare (2019)

Noah Berlow Rishi Rikhi Mathew Geltzeiler Jinu Abraham Matthew N. Svalina

Table S3. Roche Screen Merged Data - U23674. (XLSX 88 kb)

10.6084/m9.figshare.8288351

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Citations (0)

Additional file 21: of Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma

Figshare (2019)

Noah Berlow Rishi Rikhi Mathew Geltzeiler Jinu Abraham Matthew N. Svalina

Table S7. PPTI Screen Merged data - U23674. (XLSX 130 kb)

10.6084/m9.figshare.8288366

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Citations (0)

Additional file 32: of Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma

Figshare (2019)

Noah Berlow Rishi Rikhi Mathew Geltzeiler Jinu Abraham Matthew N. Svalina

Table S18. Exome Sequencing Data - PCB490. (XLSX 345 kb)

10.6084/m9.figshare.8288405

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Citations (0)

Influence of surgical margin completeness on risk of local tumour recurrence in canine cutaneous and subcutaneous soft tissue sarcoma: A systematic review and meta‐analysis

Veterinary and Comparative Oncology (2019)

Milan Milovancev Joanne Tuohy Katy L. Townsend Veronica L. Irvin

Abstract The present peer‐reviewed veterinary literature contains conflicting information regarding the impact of surgical margin completeness on risk of local tumour recurrence in canine soft tissue sarcoma (STS). This systematic review and meta‐analysis was designed to answer the clinical question: “Does obtaining microscopically tumour‐free surgical margins reduce risk for local tumour recurrence in canine cutaneous and subcutaneous STS?” A total of 486 citations were screened, 66 of which underwent full‐text evaluation, with 10 studies representing 278 STS excisions ultimately included. Cumulatively, 16/164 (9.8%) of completely excised and 38/114 (33.3%) of incompletely excised STS recurred. Overall relative risk of 0.396 (95% confidence interval = 0.248‐0.632) was calculated for local recurrence in STS excised with complete margins as compared to STS excised with incomplete margins. Risk of bias was judged to be low for all studies in terms of selection bias and detection bias but high for all studies in terms of performance bias and exclusion bias. The results of the present meta‐analysis, coupled with the results of individual previous studies, strongly suggest that microscopically complete surgical margins confer a significantly reduced risk for local tumour recurrence in canine STS. Future studies ideally should adhere to standardized conducting and reporting guidelines to reduce systematic bias.

Surgical margin

Margin (machine learning)

10.1111/vco.12479

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Citations (24)