M.-O. Timsit

Hôpital Européen Georges-Pompidou

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Arnaud Méjean

Hôpital Européen

Charles Dariane

Hôpital Européen Georges-Pompidou

François Audenet

Hôpital Européen Georges-Pompidou

Julien Branchereau

Nantes Université

Rodolphe Thuret

Hôpital Lapeyronie

S. Hurel

Hôpital Européen Georges-Pompidou

Y. Neuzillet

Université Paris-Saclay

Christophe Legendre

Université Paris Cité

F. Kleinclauss

Centre Hospitalier Universitaire de Besançon

G. Verhoest

Université de Rennes

Cooperative Institutions

Inserm

373

Assistance Publique – Hôpitaux de Paris

326

Université Paris Cité

279

Sorbonne Université

148

Centre National de la Recherche Scientifique

143

Hôpital Necker-Enfants Malades

126

Medical University of Vienna

122

Hôpital Européen Georges-Pompidou

120

University Hospital Frankfurt

114

Goethe University Frankfurt

112

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Management and Outcome After Early Renal Transplant Vein Thrombosis: A French Multicentre Observational Study of Real-Life Practice Over 24 Years

Transplant International (2023)

Ludivine Cambou C. Millet N. Terrier Paolo Malvezzi M.-O. Timsit

Early (<14 days) renal transplant vein thrombosis posttransplant (eRVTPT) is a rare but threatening complication. We aimed to assess eRVTPT management and the rate of functional renal transplantation. Of 11,172 adult patients who had undergone transplantation between 01/1997 and 12/2020 at 6 French centres, we identified 176 patients with eRVTPT (1.6%): 16 intraoperative (Group 1, G1) and 160 postoperative (Group 2, G2). All but one patient received surgical management. Patients in group G2 had at least one imaging test for diagnostic confirmation (N = 157, 98%). During the operative management of the G2 group, transplantectomy for graft necrosis was performed immediately in 59.1% of cases. In both groups, either of two techniques was preferred, namely, thrombectomy by renal venotomy or thrombectomy + venous anastomosis repair, with no difference in the functional graft rate (FGR) at hospital discharge (p = NS). The FGR was 62.5% in G1 and 8.1% in G2 (p < 0.001). Numerous complications occurred during the initial hospitalization: 38 patients had a postoperative infection (21.6%), 5 experienced haemorrhagic shock (2.8%), 29 exhibited a haematoma (16.5%), and 97 (55.1%) received a blood transfusion. Five patients died (2.8%). Our study confirms the very poor prognosis of early renal graft venous thrombosis.

Nephrology

Renal vein thrombosis

10.3389/ti.2023.10556

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Citations (2)

Clear Cell Papillary Renal Cell Carcinoma: A Recent Entity With Distinct Imaging Patterns

American Journal of Roentgenology (2019)

Mickaël Tordjman Jonathan Dbjay Alexandre Chamouni Aurélien Morini M.-O. Timsit

OBJECTIVE. Clear cell papillary renal cell carcinoma (RCC), an entity with strikingly indolent behavior, recently was added to the World Health Organization classification of renal tumors and represents the fourth most common histologic type of renal cell carcinoma. This article aims to describe the imaging features of clear cell papillary RCC along with its clinical and pathologic characteristics. MATERIALS AND METHODS. This retrospective study consisted of 27 patients with 44 clear cell papillary RCC tumors. The inclusion criteria were a pathologically proven clear cell papillary RCC and the availability of preoperative imaging including at least CT or MRI. Two experienced radiologists performed the imaging analysis independently. RESULTS. Patients (mean age, 62 years old) presented with renal failure in 26% of cases, and four had a tumor-predisposing disease. Multiple clear cell papillary RCC tumors occurred in 5 of the 27 patients. Two imaging patterns were recognizable. Solid clear cell papillary RCC (n = 23, 52%) presented as heterogeneous tumors with minor cystic changes (74%) and rarely exhibited calcifications (10%). All solid tumors showed hyperintensity on T2-weighted images compared with renal cortex and maximal enhancement on corticomedullary phase with a delayed washout. Cystic clear cell papillary RCC (n = 21, 48%) were classified as Bosniak IV (57%), III (33%), or IIF (10%), with a predominant unilocular pattern (76%). Pathologic stage according to TNM classification was mostly pT1a and low grade on nucleolar grade. All patients were alive at the date of last follow-up after treatment with no metastasis or recurrence. CONCLUSION. Clear cell papillary RCC exhibits two imaging patterns including cystic and solid in almost equal proportion. Imaging characteristics of solid clear cell papillary RCC including high signal T2 intensity and early arterial enhancement are unexpectedly distinct from papillary RCC and very similar to clear cell RCC.

10.2214/ajr.19.21681

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Citations (14)

Une étude nationale des traitements conservateurs des tumeurs du greffon rénal : vers les thérapies ablatives

Progrès en Urologie (2018)

N. Szabla S. Benbouzid S. Larré F. Gaudez X. Matillon

10.1016/j.purol.2018.07.020

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Impact de l’indication impérative sur la morbidité et les résultats carcinologiques à long terme après néphrectomie partielle

Progrès en Urologie (2009)

Yannick Rouach M.-O. Timsit Thierry Lebrét E. Fontaine Laurent Yonneau

10.1016/j.purol.2009.01.016

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Citations (6)

Chirurgie conservatrice et hypothermie rénale : bases physiologiques et technique opératoire

Annales d Urologie (2006)

Marc Colombel M.-O. Timsit Lionel Badet

10.1016/s1283-0879(06)41526-2

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Citations (0)

Néphrectomie partielle du transplant rénal : étude multicentrique

Progrès en Urologie (2014)

X. Tillou K. Guleryuz A. Doerfler H. Bensadoun Damien Chambade

10.1016/j.purol.2014.08.157

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Citations (1)

Gestion des sténoses urétérales : les alternatives à la sonde jj au long cours

Progrès en Urologie (2018)

C. Pettenati Sandrine Roux Charles Dariane M. Sbizerra I. Dominique

10.1016/j.purol.2018.07.030

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Citations (0)

[Polyneuritis of isoniazide].

PubMed (1956)

E Benhamou M.-O. Timsit

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Citations (3)

Use of forearm free‐flap phalloplasty in bladder exstrophy adults

BJU International (2008)

M.-O. Timsit Pierre E. Mouriquand A. Ruffion A. Bouillot Diala Dembelé

To assess the long-term outcome and cosmetic results of forearm free-flap phalloplasty for correcting micropenis associated with bladder exstrophy in men.From 1992 to 2000, six men with bladder exstrophy and unsatisfactory penile appearance underwent phalloplasty at our institution. The mean (range) follow-up was 113 (62-153) months. The surgical procedure consisted of a modified radial free-flap phalloplasty and prosthesis implantation. One-stage urethroplasty was electively performed according to the patient's voiding pattern. Early and late complications were recorded and quality of life after phalloplasty was assessed.The mean (range) age was 21.2 (17-26) years and flap survival was 100%. Two incontinent patients underwent immediate perineal urethrostomy. One sepsis occurred, requiring the removal of the penile prosthesis and a cutaneous continent urinary diversion; this patient was the only one to complain about the outcome. Two anastomotic urethral strictures were conservatively treated by endoscopic urethrotomy and only one patient underwent subsequent urethral self-dilatations. Five patients were very satisfied with the cosmesis of the neophallus and three patients reported having regular sexual intercourse.Although short, this series indicates the low incidence of early complications and the excellent long-term satisfaction with forearm free-flap phalloplasty in bladder exstrophy. Phalloplasty has potential indications when adult exstrophy patients are dissatisfied with the cosmetic appearance of their external genitalia or have unsatisfactory sexual intercourse.

Phalloplasty

Epispadias

Cosmesis

Penile prosthesis

Cloacal exstrophy

10.1111/j.1464-410x.2008.08286.x

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Citations (28)

Nephron-Sparing Surgery for Renal Cell Carcinoma: Detailed Analysis of Complications Over a 15-Year Period

European Urology (2006)

G. Pasticier M.-O. Timsit Lionel Badet Luís de la Torre Abril Mohamed Halila

Kidney cancer

10.1016/j.eururo.2005.12.049

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Citations (114)