K. Turgay Akgül

Sağlık Bilimleri Üniversitesi

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Ali Ayyıldız

Adıyaman University

Cankon Germíyanoğlu

Ondokuz Mayıs University

Barış Nuhoğlu

Biruni University

HÜ

Hüseyin Üstün

Izmir University

AŞ

Aytaç Şahin

Fatih Sultan Mehmet Eğitim Ve Araştırma Hastanesi

MÇ

Muzaffer Çaydere

Ministry of Health

Musab Ali Kutluhan

Ankara Yıldırım Beyazıt University

Tuncay Toprak

Sağlık Bilimleri Üniversitesi

Ayhan Verit

Sağlık Bilimleri Üniversitesi

Barış Nuhoğlu

Biruni University

Cooperative Institutions

Sağlık Bilimleri Üniversitesi

Ministry of Health

University of Health Science

Education Training And Research

Izmir Tepecik Eğitim ve Araştırma Hastanesi

Fatih Sultan Mehmet Eğitim Ve Araştırma Hastanesi

Izmir University

Hacettepe University

University of Health Sciences

Izmir Kâtip Çelebi University

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Papers

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Can second to fourth finger ratio play a role in determining the risk of benign prostatic enlargement

Andrologia (2020)

Tuncay Toprak Umut Arslan Musab Ali Kutluhan Aytaç Şahin K. Turgay Akgül

Benign prostatic enlargement (BPE) is a disease that testosterone plays a role in its aetiology. Second to fourth finger ratio is a marker of prenatal androgenic exposure and may be a risk factor for several androgen-related diseases such as BPE. In this study, we investigated the relationship between the second to fourth finger ratio and BPE. A total of 63 patients with BPE were included for study group, and age-matched 63 healthy patients were included as a control group. Finger was measured by the distance from the proximal crease to the tip by using a digital caliper. The mean age of patients with BPE and non-BPE was 62 ± 8.9 and 61.5 ± 7.1 years respectively. There was statistically significant difference between groups in terms of prostate-specific antigen levels, prostate volumes and international prostate symptom scores. The mean finger ratios for right and left hand were 0.97 ± 0.03, 0.99 ± 0.03(p = .001) and 0.93 ± 0.15, 0.98 ± 0.03(p < .001) for BPE and non-BPE groups respectively. Men with a lower second to fourth finger ratio have higher risk of developing BPE than men without BPE. Therefore, the second to fourth finger ratio, which is indicative of prenatal androgen exposure, can be used as a marker of BPE risk.

Etiology

10.1111/and.13529

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Citations (2)

Investigation of factors affecting result of distal hypospadias repair: Comparison of two techniques

Urology (2006)

Cankon Germíyanoğlu Barış Nuhoğlu Ali Ayyıldız K. Turgay Akgül

Chordee

Urinary diversion

10.1016/j.urology.2006.01.090

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Citations (19)

Comparison of transurethral prostate resection and plasmakinetic prostate resection according to cautery artefacts in tissue specimens

International Urology and Nephrology (2007)

K. Turgay Akgül Ali Ayyıldız Barış Nuhoğlu Muzaffer Çaydere Hüseyin Üstün

Coagulative necrosis

10.1007/s11255-007-9174-1

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Citations (19)

Does duration of stenting increase the risk of clinical infection?

Archivio Italiano di Urologia e Andrologia (2020)

Tuncay Toprak Aytaç Şahin Musab Ali Kutluhan K. Turgay Akgül Yavuz Onur Danacıoğlu

Objective: We investigated when an indwelling ureteral catheter should be withdrawn for infection and evaluated the importance of urinary cultures in identifying colonized microorganisms and define the bacterial flora encountered in the study. Moreover, this study tried to determine the clinical role of stent culture in clinical practice. Materials and methods: The study was conducted between June 2018 and February 2019. Patients with ureteral stent implantation after endoscopic ureteral stone treatment were divided into two groups and each group consisted of 45 patients. Ureteral catheter was removed 15 and 30 days after ureteral stone treatment in group 1 and 2, respectively, and transferred for microbiological examination. The urine culture was obtained before and after ureteral stent implantation. The groups were compared in terms of demographics, urine and catheter cultures results. Urine analysis and catheter culture results were also compared. Results: Demographic data of patients were similar in both groups. 3 patients in group 1 and 12 patients in group 2 had positive urine culture before catheter retraction; 2 of 45 and 6 of 45 patients had positive catheter culture in group 1 and 2, respectively. Although 2 patients in group 1 and 4 patients in group 2 had urine culture sterile, they had growth in catheter culture. In Group 1, 1 of the microorganisms was E. fecalis and 1 was E. coli. In Group 2, 2 cases were E. fecalis, 3 were E. coli and 1 was MRSE. There was no significant difference between the urine analysis results of the patients before catheter retraction and catheter culture positivity. Conclusions: Pre-operative urine culture does not exclude catheter colonization, and the prolonged duration of the catheter associated with greater colonization and may be associated urinary tract infection. Ureteral catheter should be removed as early as possible.

10.4081/aiua.2019.4.237

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Citations (9)

Erkek hastalarda böbrek nakli sonrası cinsel işlevler

Türk Üroloji Dergisi/Turkish Journal of Urology (2009)

Ali Şahin Ahmet Cihan K. Turgay Akgül Ömer Demir Alp Gürkan

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Citations (1)

An Experimental Study: Does Topically Applied Sildenafil Citrate (Sildegra ® ) Have an Effect on the Preservation of the Viability of the Graft in Full-Thickness Tubed Free Skin Grafts?

TURKISH JOURNAL OF MEDICAL SCIENCES (2006)

Ali Ayyıldız K. Turgay Akgül Barış Nuhoğlu Emre Hurі Muzaffer Çaydere

Aim: In this study we investigated the effectiveness of topically applied sildenafil citrate in increasing graft viability. Methods: The study included 15 rats (5 rats each in control, sham, and study groups). Physiological saline (1 ml) was given to the sham group and sildenafil citrate solution (0.5 mg/kg/day in 1 ml saline) to the study group. One week later the grafts were evaluated by histopathological investigation. Results: The feeding tube in the control and sham groups had totally melted due to xylol. Widespread neutrophil leukocyte infiltration, a thin full-thickness free tubed graft in the periphery, widespread neutrophil and inflammation zones lower down and widespread necrotic foci were present at the site of the tube. However, in the sildenafil group, a widespread foreign body reaction was observed. There was an increase in the granulation tissue. Inflammation, necrosis, and fibroblastic reactions were present. In contrast to the control and sham groups, new vessel formations were seen. Conclusion: It was observed that topical sildenafil citrate application had no effect on the increase in viability of free tubed grafts.

Granulation tissue

Physiological saline

Cellular infiltration

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Citations (4)

USE OF PORCINE SMALL INTESTINAL SUBMUCOSA IN BLADDER AUGMENTATION IN RABBIT: LONG‐TERM HISTOLOGICAL OUTCOME

ANZ Journal of Surgery (2008)

Ali Ayyıldız K. Turgay Akgül Emre Hurі Barış Nuhoğlu Bülent Kılıçoğlu

To investigate long-term histological features of bladder augmentation using porcine small intestine submucosa (SIS) in a rabbit model.Sixteen New Zealand rabbits were used. Porcine SIS was provided by a manufactured formation derived from the pig. After partial cystectomy was carried out on the bladder, a single layer of SIS (Cook-SIS Technology, Cook Biotech Incorporated, West Lafayette, IN, USA) (2 x 5 cm) was sewn to bladder with continuous 5/0 vicryl suture material in a watertight manner. Urinary diversion was not used. The rabbits were killed 12 months later and perivesical fat was removed together with bladder. The 5-microm preparations taken from the samples were stained with haematoxylin-eosin and Mason's trichrome dye. S-100 and F8 stains were also used for immunohistochemical investigations.The macroscopic view of bladder was normal. SIS was indistinguishable from normal bladder wall, but the region of the graft had a slight white coloration. Microscopic observations showed the continuity of transitional epithelium of host bladder tissue on SIS material. Detrusor and serosal layers were formed and these layers were indistinguishable from host bladder. Fibroblasts were scattered among the collagen fibrils. New vessel formations were present without lymphatic proliferation. Nerve regeneration was excellent. No inflammation was observed in normal and regenerated bladder wall.At the end of 12 months, the long-term histological features of bladder augmentation with porcine SIS in a rabbit model, such as presence of new vessel formations, nerve regeneration, collagen and smooth muscle regenerations, which were indistinguishable from original bladder, and the absence of inflammation, showed that SIS seems to be a viable alternative to the use of intestine in bladder augmentation.

Haematoxylin

Submucosa

Bladder augmentation

Masson's trichrome stain

Muscular layer

Histology

Eosin

10.1111/j.1445-2197.2007.04361.x

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Citations (43)

The effects of cigarette smoking on prostate-specific antigen in two different age groups

Canadian Urological Association Journal (2013)

Gökhan Koç K. Turgay Akgül Yüksel Yılmaz Alper Dirik

Background: We investigate the effects of cigarette smoking on prostate-specific antigen (PSA) using 2 different age groups.Methods: The study was carried out between January 2007 and October 2011 with men; the 2 sets of age groups were: 25 to 35 years and 50 to 70 years old. The participants were divided into 4 groups. Of the 25 to 35 age range, smokers were Group 1, and non-smokers were Group 2; of the 50 to 70 age range, smokers were Group 3 and non-smokers Group 4. In addition, for the 50 to 70 age group, the International Prostate Symptom Score was completed, digital rectal examination was performed, and transabdominal prostate volume was measured. We wanted to see whether prostate-specific antigen (PSA) levels showed a difference between the 2 age groups.Results: There were 114 patients in Group 1, 82 in Group 2,90 in Group 3, and 102 in Group 4. The mean PSA level was 0.7 ± 0.28 ng/mL for Group 1, and 0.6 ± 0.27 ng/mL for Group 2 (p = 0.27), and there was no statistically significant difference between the 2 groups. The mean PSA was 2.5 ± 1.8 ng/mL for Group 3, and 2.1 ± 2.0 ng/mL (p = 0.59) for Group 4, and there was no statistically significant difference between the these 2 age groups.Interpretation: Cigarette smoking effects various hormone levels. Different from previous studies, the PSA level was higher in smokers compared to nonsmokers, although it was not statistically significant. Our study is limited by the small numbers in our study groups and the lack of PSA velocity data.

Age groups

Rectal examination

Group B

10.5489/cuaj.358

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Citations (8)

Effect of phospodiesterase 5 inhibitors on apoptosis and nitric oxide synthases in testis torsion: an experimental study

Pediatric Surgery International (2007)

Hüseyin Üstün K. Turgay Akgül Ali Ayyıldız Hatice Yağmurdur Barış Nuhoğlu

Vardenafil

10.1007/s00383-007-2058-8

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Citations (33)

Laser-puncture Versus Electrosurgery-incision of the Ureterocele in Neonatal Patients.

PubMed (2018)

Ahsen Karagözlü Akgül Dursun Ünal Murat Demirbaş Sedat Öner Murat Uçar

To compare the holmium-laser puncture and electrosurgery-incision in neonates with intravesical ureterocele.We retrospectively analyzed the results of laser-puncture of ureterocele (LP group) in 12 patients (mean age 9.8 days, range 4-28) and electrosurgery-incision in 20 patients (ES group) (mean age 10.2 days, range 6-28), treated at our institution. Patients had their records reviewed for preoperative findings, endoscopic procedure description, and postoperative outcomes.There was the need for retreatment in one (8.3%) patient in LP group and in four (20%) patients in ES group (P = .626). Duration of general anesthesia in LP and ES groups was 16 (range, 10-24) minutes and 15 (range, 10-20) minutes, respectively (P = .355). There was no statistically significant difference in terms of hospitalization (LF group one day, ES group 1.35 days) (P = .286). Complications were not found in LP group. There were two (10%) patients with pyelonephritis after the treatment in ES group (P = .516). After one month, obstruction was observed on ultarsound examination in one (8.3%) and two (10%) patients, respectively. After three months, obstructionwas not found in any patient in both groups. After six months, vesicoureteral reflux was found in one (8.3%) patient after laser-puncture of the ureterocele and in 13 (65%) patients after electrosurgery-incision (P = .003).Both laser-puncture and electrosurgery-incision endoscopic techniques are highly effective in relieving the obstruction. There is no significant difference regarding hospitalization, need for retreatment and the occurrence of complications. The incidence of de novo vesicoureteral reflux is significantly lower in patients treated with holmium-laser, as well as the need for upper pole partial nephrectomy.

Ureterocele

Electrosurgery

10.22037/uj.v0i0.3805

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Citations (15)