Ho Kang

Seoul National University Hospital

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Chul‐Kee Park

Seoul National University Hospital

Yong Hwy Kim

Seoul National University Hospital

Min‐Sung Kim

Seoul National University Hospital

Jin Wook Kim

Seoul National University Hospital

Jae‐Kyung Won

Seoul National University Hospital

Kyung‐Min Kim

Seoul National University Hospital

Tamrin Chowdhury

Seoul National University Hospital

Hyeon Jong Yu

Seoul National University Hospital

Yun‐Sik Dho

National Cancer Center

Sung‐Hye Park

Seoul National University Hospital

Cooperative Institutions

Seoul National University Hospital

122

Seoul National University

120

New Generation University College

National University College

Seoul National University Bundang Hospital

Yonsei University

Korea University

Sungkyunkwan University

University of Ulsan

Samsung Medical Center

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P1.31 Snp Q787Q of Egfr Gene and Efficacy of Egfr-Tki in Patients With Non-Small Cell Lung Cancer

Annals of Oncology (2012)

Y.C Kim Tae Won Jang In‐Jae Oh K.S Kim Hee‐Jung Ban

SNP

10.1016/s0923-7534(20)31322-3

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Primary Intracranial Ewing Sarcoma With EWSR1-FLI1 Gene Translocation Mimicking a Meningioma and a Multidisciplinary Therapeutic Approach: A Case Report and Systematic Review of Literatures

Brain Tumor Research and Treatment (2023)

C.Y. Hyun Y. S. Lee Ho Kang Hyun Joo Park Koung Jin Suh

Ewing sarcoma and peripheral primitive neuroectodermal tumor (ES/pPNET) is an undifferentiated malignant tumor that is most prevalent in children and young adults and often radiologically mimics a meningioma. A 38-year-old female patient visited our hospital with complaints of right-sided tinnitus, right hemiparesis, and imbalance. She underwent preoperative imaging and was subsequently diagnosed as having a meningioma on the petrous ridge. After partial resection, EWSR1-FLI1 gene fusion was confirmed, and she was diagnosed with ES/pPNET. The tumor was successfully treated using a multidisciplinary approach of adjuvant chemo- and radiotherapy. This case is noteworthy because it is an extremely rare case of an intracranial ES/pPNET, and it is worth sharing our clinical experience that the tumor was successfully treated through a multidisciplinary therapeutic approach even though complete resection was not achieved.

FLI1

Ewing's sarcoma

10.14791/btrt.2023.0030

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하수슬러지 케이크 열수분해 탈리액의 혐기성 분해 특성

대한환경공학회지 (2015)

Ho Kang 오백용 신경숙

본 연구에서는 슬러지 케이크를 열수분해한 탈리액을 대상으로 혐기소화특성을 평가하였으며, 슬러지 탈수케이크의 열수분해후 성상변화 및 열수분해 탈리액의 MAP결정화, MAP결정화 상등액을 이용한 혐기소화공정효율을 고찰하였다. 탈리액의 MAP결정화는 Mg:P의 비가 1.5:1, pH가 9.5인 조건이 최적이었으며, 이때 MAP생성으로 인해 열수분해 탈리액의 암모니아성 질소는 50%, 인산염은 97%가 제거되어 열수분해 탈리액의 혐기소화 전처리 시 효과적임을 알 수 있었다. 기질 대미생물비(S/I) 0.5 조건에서 중온 회분식 혐기소화조 운전결과 MAP 결정화를 거친 열수분해 탈리액의 최종생분해도는 63%였으며, 분해속도상수 k1은 0.207 day-1로 17일 동안 이분해성 기질비율(S1)이 90% 분해되었고, 나머지 10% (S2)는 k2 (0.024 day-1)의 느린 속도로 분해되어 열수분해로 인해 슬러지의 생분해성이 높아짐을 알 수 있다. 열수분해 탈리액을 MAP결정화한 후, 탈리액을 대상으로 SCFMR형태의 혐기조를 운전한 결과 HRT 20일(OLR 1.43 g VS/L-d)에서 평균 0.45 v/v-d의 Biogas가 발생하였으며, TVS제거효율은 37~41% 범위로 우수한 혐기소화효율을 나타내었다.

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Safety of endoscopic endonasal biopsy for the pituitary stalk-hypothalamic lesions

Pituitary (2021)

Ho Kang Kyung‐Min Kim Min‐Sung Kim Jung Hee Kim Chul‐Kee Park

Pituitary stalk

10.1007/s11102-021-01181-0

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Radiological assessment schedule for 1p/19q-codeleted gliomas during the surveillance period using parametric modeling

Neuro-Oncology Advances (2021)

Ho Kang Jong Jin Lee So Young Ji Seung Won Choi Kyung‐Min Kim

Abstract Background There have been no evidence-based guidelines on the optimal schedule for the radiological assessment of 1p/19q-codeleted glioma. This study aimed to recommend an appropriate radiological evaluation schedule for 1p/19q-codeleted glioma during the surveillance period through parametric modeling of the progression-free survival (PFS) curve. Methods A total of 234 patients with 1p/19q-codeleted glioma (137 grade II and 97 grade III) who completed regular treatment were retrospectively reviewed. The patients were stratified into each layered progression risk group by recursive partitioning analysis. A piecewise exponential model was used to standardize the PFS curves. The cutoff value of the progression rate among the remaining progression-free patients was set to 10% at each scan. Results Progression risk stratification resulted in 3 groups. The optimal magnetic resonance imaging (MRI) interval for patients without a residual tumor was every 91.2 weeks until 720 weeks after the end of regular treatment following the latent period for 15 weeks. For patients with a residual tumor after the completion of adjuvant radiotherapy followed by chemotherapy, the optimal MRI interval was every 37.5 weeks until week 90 and every 132.8 weeks until week 361, while it was every 33.6 weeks until week 210 and every 14.4 weeks until week 495 for patients with a residual tumor after surgery only or surgery followed by radiotherapy only. Conclusions The optimal radiological follow-up schedule for each progression risk stratification of 1p/19q-codeleted glioma can be established from the parametric modeling of PFS.

10.1093/noajnl/vdab069

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Positional effect of preoperative neuronavigational magnetic resonance image on accuracy of posterior fossa lesion localization

WFNOS 2022 Abstract Book (2022)

Yun‐Sik Dho Hyeong Cheol Moon Kyung Min Kim Ho Kang Min‐Sung Kim

Posterior fossa

10.14791/btrt.2022.10.f-1088

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도시 하수의 생물학적 고도처리를 위한 분리막 공정의 개발 및 동역학적 계수 산정 연구

대한환경공학회지 (2009)

박종부 박승국 허형우 Ho Kang

본 연구는 혐기조, 안정화조, 무산소조, 막분리호기조로 구성된 membrane bioreactor의 운영을 통하여 도시 하수의 영양염류 제거 특성을 규명하였다. 수리학적 체류시간(HRT)과 슬러지 체류시간(SRT) 및 운영 여과 플럭스의 평균값은 각각 6.2시간, 34.1일과 19.6 L/m2/hr (LMH)이었으며, 공정을 운전한 결과, COD(Cr), SS, TN 및 TP의 평균 제거율은 각각 94.3%, 99.9%, 69.4% 및 74.6%이었다. 슬러지 생산계수, SDNR, SNR, SPPR 및 SPUR은 각각 0.653 kgVSS/kgBOD/d, 0.044 mgNO₃-N/mgVSS/d, 0.035 mgNH₄-N/mgVSS/d, 51.0 mgP/gVSS/d 및 5.4 mgP/gVSS/d였다. 또한, 생산된 슬러지의 평균 질소 및 인 함량은 각각 8.86%와 3.5%였다.

Membrane bioreactor

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Treatment of Clival Giant Cell Tumor: A Case Report and Literature Review

Brain Tumor Research and Treatment (2024)

Jung Yeop Yang Ho Kang Yong Hwy Kim

Giant cell tumors (GCTs) are locally aggressive primary bone tumors of osteoclast-like cells. Most GCTs occur within the long bones, and primary GCTs involving the clivus are extremely rare. We present the case of an 18-year-old boy with binocular horizontal diplopia with an insidious onset who was found to have a hypointense enhancing mass involving the clivus and left side dorsum sellae on magnetic resonance images. The tumor was completely resected via an endoscopic endonasal transclival approach, and histopathologic examination via immunohistochemistry indicated a GCT. The patient's left abducens nerve palsy improved slightly after surgery. Because of the rarity of GCTs, there is no consensus about the definitive treatment protocol. However, we suggest that gross total resection is the treatment of choice, and denosumab plays a critical role in patients with subtotal resection.

10.14791/btrt.2024.0010

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Pyridine-NBD: A homocysteine-selective fluorescent probe for glioblastoma (GBM) diagnosis based on a blood test

Analytica Chimica Acta (2022)

Youngwoong Kim Jong Min An Jaehoon Kim Tamrin Chowdhury Hyeon Jong Yu

Moiety

Thiol

10.1016/j.aca.2022.339678

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Citations (18)

Adjuvant radiotherapy versus observation following gross total resection for atypical meningioma: a systematic review and meta-analysis