Christine Enjalbal

Research Field

Unusual behavior of pyrazolo[1,2‐a]pyrazoles in fast atom bombardment (fab) and frit‐fast atom bombardment (Frit‐FAB) mass spectrometry. Influence of the matrix

Journal of Heterocyclic Chemistry (1998)

Christine Enjalbal Jean‐Louis Aubagnac Swiatoslaw Trofimenko Rosa M. Claramunt Dionísia Sanz

Abstract The nature of the matrix used in Fast Atom Bombardment (FAB) mass spectrometry analyses of pyrazolo[1,2‐ a ]pyrazoles was found to influence significantly their positive and negative ions mass spectra. Indeed the use of glycerol provided an abundant ion corresponding to the protonated molecule (M+H) + whereas the meta ‐nitrobenzyl alcohol favored the formation of the radical ion M +° . Such results which are in accordance with the oxidoreduction properties of the matrices studied were also established in Frit‐FAB mass spectrometry analyses of pyrazolo[1,2‐ a ]pyrazoles.

Fast atom bombardment

Frit

Matrix (chemical analysis)

10.1002/jhet.5570350631

Cite

Citations (3)

Disclosing the Preferential Mercury Chelation by SeCys Containing Peptides over Their Cys Analogues

Inorganic Chemistry (2023)

Mikel Bernabeu de Maria Diego Tesauro Filippo Prencipe Michele Saviano Luigi Messori

Methylmercury, mercury (II), and mercury (I) chlorides were found to react with vasopressin, a nonapeptide hormone cyclized by two cysteine residues, and its mono- and diselenium analogues to form several mercury-peptide adducts. The replacement of Cys by SeCys in vasopressin increased the reactivity toward methylmercury, with the predominant formation of -Se/S-Hg-Se-bridged structures and the consequent demethylation of methylmercury. In competitive experiments, CH3HgCl reacted preferentially with the diselenium analogue rather than with vasopressin. The diselenium peptide also showed the capability to displace the CH3Hg moiety bound to S in vasopressin. These results open a promising perspective for the use of selenopeptides for methylmercury chelation and detoxification strategies.

Mercury

Methylmercury

Moiety

Residue (chemistry)

10.1021/acs.inorgchem.3c01708

Cite

Citations (4)

Silica nanoparticles pre-spotted onto target plate for laser desorption/ionization mass spectrometry analyses of peptides

Analytica Chimica Acta (2012)

Mathieu Dupré Sonia Cantel Jean‐Olivier Durand Jean Martínez Christine Enjalbal

MALDI imaging

Sample Preparation

Matrix (chemical analysis)

Repeatability

10.1016/j.aca.2012.06.037

Cite

Citations (25)

Laser desorption ionization mass spectrometry of protein tryptic digests on nanostructured silicon plates

Journal of Proteomics (2012)

Mathieu Dupré Yannick Coffinier Rabah Boukherroub Sonia Cantel Jean Martínez

Peptide mass fingerprinting

10.1016/j.jprot.2011.12.039

Cite

Citations (33)

Synthesis of peptide-grafted comb polypeptidesviapolymerisation of NCA-peptides

Chemical Communications (2012)

Hiroshi Enomoto Benjamin Nottelet Al Halifa Soultan Christine Enjalbal Mathieu Dupré

A straightforward synthesis of comb-polypeptides of repeated peptide sequences was developed. These polypeptides were obtained by ROP of defined NCA without any post-polymerization grafting. The key to this strategy relies on the preparation of pure NCA bearing a peptide sequence on its side chain, by an original solid supported methodology.

Sequence (biology)

Peptide Synthesis

10.1039/c2cc37597d

Cite

Citations (14)

Désorption Ionisation Laser Assistée par Surface (SALDI-MS) pour la détection intracellulaire de biomarqueurs spécifiques de la maladie d’Alzheimer.

Christine Enjalbal Claudia Bich Aline Cournut Yannick Coffinier Paul Moustiez

Source

Cite

Citations (0)

Revealing C-terminal peptide amidation by the use of the survival yield technique

Analytical Biochemistry (2022)

Elodie Logerot Guillaume Cazals Antony Memboeuf Christine Enjalbal

Sequence (biology)

Posttranslational modification

Tandem

Tandem mass tag

10.1016/j.ab.2022.114823

Cite

Citations (2)

Multiplexed targeted analysis of polyunsaturated fatty acids and oxylipins using liquid chromatography-tandem mass spectrometry

STAR Protocols (2023)

Evgenia Turtoi Jérémy Jeudy Gilles Valette Christine Enjalbal Isabelle K. Vila

Polyunsaturated fatty acids (PUFAs) and their oxidized products (oxylipins) are important mediators in intra- and extra-cellular signaling. We describe here the simultaneous quantification of 163 PUFAs and oxylipins using liquid chromatography-mass spectrometry (LC-MS). The protocol details steps for PUFA purification from various biological materials, the conditions for LC-MS analysis, as well as quantitative approaches for data evaluation. We provide an example of PUFA quantification in animal tissue along with the bioinformatic protocol, enabling efficient inter-sample comparison and statistical analysis. For complete details on the use and execution of this protocol, please refer to Vila et al.,

10.1016/j.xpro.2023.102226

Cite

Citations (1)

Quantitative determination of rocuronium in human plasma by liquid chromatography–electrospray ionization mass spectrometry

Journal of Chromatography A (2001)

Christine Farenc Christine Enjalbal P. Sánchez Françoise Bressolle Michel Audran

10.1016/s0021-9673(00)01164-x

Cite

Citations (29)

合成ペプチド類のキラル分析 N-末端開裂で誘導されるジアステレオ異性のカルバモイルエステル類の高性能液体クロマトグラフィー

Journal of The Chemical Society-perkin Transactions 1 (1992)

John Stanley Herbert Davies Christine Enjalbal Gareth Llewellyn