Hana Konečná

Nemocnice České Budějovice

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Zbyněk Zdráhal

Central European Institute of Technology

Jiřı́ Doškař

Masaryk University

Roman Pantůček

Masaryk University

OŠ

Ondřej Šedo

Central European Institute of Technology

Jan Preisler

Masaryk University

Vladislava Růžičková

Masaryk University

Břetislav Brzobohatý

Mendel University in Brno

I Kalina

University of Pavol Jozef Šafárik

Luděk Eyer

Czech Academy of Sciences, Biology Centre

A Ondrusseková

University of Veterinary Medicine in Košice

Cooperative Institutions

Masaryk University

Slovak Academy of Sciences

Comenius University Bratislava

Institute of Plant Genetics, Polish Academy of Sciences

Charles University

Central European Institute of Technology

Czech Academy of Sciences

Pharmac

Central European Institute of Technology – Masaryk University

University Hospital Brno

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Integrace žákyně s poruchou autistického spektra do třídy žáků s jiným druhem postižením

Hana Konečná

Diplomova prace je zaměřena na zjistěni a analyzovani pozitiv a negativ integrace žakyně s poruchou autistickeho spektra do třidy žaků s jiným druhem postiženi. Teoreticka cast se sklada ze tři kapitol. Prvni kapitola se věnuje terminologii, etiologii, charakteristice a klasifikaci poruch autistickeho spektra. Druha kapitola vymezuje legislativni normy, poradenský system a možnosti edukace žaků s PAS. Třeti kapitola se zabýva integraci a inkluzi žaků s poruchami autistickeho spektra. Prakticka cast je výzkumným setřenim, ktere bylo realizovano z pohledu asistentky pedagoga, jež se podilela na výchově a vzdělavani integrovane žakyně s poruchou autistickeho spektra ve třidě žaků s tělesným postiženim v průběhu dvou let. Výzkum je doplněn informacemi ziskanými z rozhovorů se zainteresovanými pedagogy a matkou žakyně.

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Current possibilities and risks of donating some tissues, cells, and organs from living donors.

PubMed (2023)

Hana Konečná Zuzana Čermáková Ivana Honzová Roman Chmel Pavel Jindra

Transfusion, transplantation, and regenerative medicine are rapidly developing fields. The authors of the text want to inform about upcoming legislative changes at the EU level and briefly describe and compare the difficulty of some donation procedures from the point of view of a living donor, as well as their risks, including psychosocial risks. The study is based on a qualitative expert investigation. Comparing the complexity of procedures from the perspective of donors is important, for example, for setting compensations. The tables show that the current compensations are disproportionate.

Regenerative Medicine

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Introductory: On infertility, hope, the search for certainty and the qualitative approach

Human Affairs (2014)

Hana Konečná

Certainty

10.2478/s13374-014-0216-y

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P–474 Psychosocial aspects of fertility preservation options for young cancer patients in the Czech Republic: a qualitative study

Human Reproduction (2021)

Hana Konečná Karolína Nováková

Abstract Study question What is the real accessibility of fertility preservation techniques and its perception by patients in the Czech Republic? Summary answer Fertility preservation options are not offered on a routine basis and often are not part of a treatment plan. Patients wish to be adequately informed. What is known already Every year, more than 82.000 people in the Czech Republic develop cancer. The incidence of newly diagnosed cancers in individuals in their reproductive age represents 4.4% of all newly diagnosed oncological diseases. Because the prognosis of treatment in this group of patients is very favourable, the priority in treatment is the emphasis on quality of life after surviving. One of the important parameters of quality of life for many people is the ability to reproduce and the possibility of having a genetic bond to their children. Study design, size, duration This qualitative study was conducted in 2019 and relied on explorative in-depth semi-structured interviews. Participants were chosen through occasional sampling. Participants/materials, setting, methods We interviewed 13 cancer patients/survivors in their reproductive age (aged 21 to 36; 7 females and 6 males); 4 close family members of young cancer patients; and 8 experts from relevant professional fields. Data gathered from semi-structured interviews were analysed by interpretative phenomenological analysis. Main results and the role of chance Cancer was perceived as a threat to life and one’s safety. It causes uncertainty and a feeling of loss of control. It also has a negative impact on a self-concept. Loss of fertility was perceived as a “injury of personality”. The possibility of maintaining fertility has increased the subjectively experienced quality of life. They make decisions under great time pressure, in a mentally demanding situation. They are usually in the early stages of coping with the diagnosis. The main factors that influenced the respondents’ decision were the amount and quality of information, psychological stress and time pressure. Patients and their families are interested in being informed about the risks that the disease and its treatment pose to their reproductive health. They want to be able to decide whether to undergo any of the fertility protection techniques. They want to keep their future open. It is therefore desirable that, within oncofertility, we focus on the process of passing on information and supporting decision-making on issues of fertility and its protection. A tool that could be a good informational platform may be so-called decision aid – a tool used to inform patients about available treatments, along with potential benefits, risks and costs. Limitations, reasons for caution As all qualitative data, our findings cannot be generalized. Selection bias could have occurred because it is likely that those interested and open to sharing participated. Wider implications of the findings: Oncofertility treatment is highly relevant and should be offered and discussed with all patients in their reproductive age. Addressing fertility preservation options should be a part of cancer treatment plan of all these patients. Trial registration number 0

Oncofertility

10.1093/humrep/deab130.473

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Náhradní mateřství v České republice: způsoby hledání náhradní matky. Surrogate motherhood in the Czech Republic: ways to seek a surrogate mother.

Časopis zdravotnického práva a bioetiky (2018)

Karolína Nováková Hana Konečná Markéta Sudová

Abstract : Surrogate motherhood (SM) is a procedure, when a woman undergoes assisted reproduction, pregnancy and childbirth in order to give up her child and transfer parental rights and obligations someone else, who she previously agreed with. The complexity of the procedure entails many legal problems; the most important are the determination of legal parenthood, enforceability of agreements concluded before the child's birth or before commencement of treatment, compensation of costs, registration of the newborn, the search for a surrogate mother, the right of the child to know her/his parents. Our article is a response to the article Surrogate motherhood in Legal Practice , published in JMLB (2015, Vol. 5, No. 2), and we mainly address the issue of seeking a surrogate mother. Abstrakt : Nahradni mateřstvi (NM) je procedura, kdy asistovanou reprodukci, těhotenstvi a porod podstoupi žena s cilem vzdat se narozeneho ditěte a rodicovska prava a povinnosti převest na někoho jineho, předem domluveneho. Složitost procedury s sebou přinasi mnoho pravnich problemů; hlavnimi jsou urceni pravniho rodicovstvi, vymahatelnost dohod uzavřených před porodem ditěte ci před zahajenim lecby, kompenzace nakladů, registrace novorozence, cesty hledani nahradni matky, pravo ditěte znat sve rodice. Nas clanek je reakci na clanek Nahradni mateřstvi v pravni praxi , uveřejněný v Casopise zdravotnickeho prava a bioetiky (2015, Vol. 5, No. 2), reagujeme předevsim na problematiku hledani nahradni matky.

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The identification of catalytic pentad in the haloalkane dehalogenase DhmA from Mycobacterium avium N85: Reaction mechanism and molecular evolution

Journal of Structural Biology (2006)

Martina Pavlová Martin Klvaňa Andrea Jesenská Zbyněk Prokop Hana Konečná

Dehalogenase

Residue (chemistry)

Thermus thermophilus

Site-directed mutagenesis

10.1016/j.jsb.2006.09.004

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Na cestě za dítětem - dvě malá křídla

Hana Konečná

Publikace v cestině prvni sveho druhu pojednava o otazkach spojených s neplodnosti, poskytuje informace o přicinach neplodnosti, diagnostických metodach a terapeutických postupech, jejich psychicke, fyzicke, casove, financni a jine narocnosti, dale o formach nahradni rodicovske pece a otazkach spojených s adoptivnim rodicovstvim... Prace se opira o konkretni material, shromažděný autorkou při výzkumu mezi nedobrovolně bezdětnými pary. (dvě mala křidla)

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Adaptive response to ionizing radiation in normal and aneuploid human lymphocytes.

PubMed (1994)

I Kalina Hana Konečná G Némethová N. Račeková

The ability to induce an adaptive response by low doses of gamma rays was studied in normal and trisomic lymphocytes (47, XX or XY, +21). The results indicate the presence of an adaptive response in lymphocytes of 3 normal donors, but in lymphocytes of 5 donors with trisomy 21 no significant adaptive response after irradiation with a low dose of gamma rays was found. There was similar chromosomal radiosensitivity in normal and trisomic lymphocytes (47, XX or XY, +21) irradiated with 1.50 Gy at the 48th hour after stimulation.

Radiosensitivity

Trisomy

Adaptive response

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Complete genome analysis of two new bacteriophages isolated from impetigo strains of Staphylococcus aureus

Virus Genes (2015)

Tibor Botka Vladislava Růžičková Hana Konečná Roman Pantůček Ivan Rychlı́k

Siphoviridae

Temperateness

Phage typing