Jason H. Rogers

University of California Davis Medical Center

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Gagan D. Singh

University of California Davis Medical Center

Thomas W. Smith

University of California Davis Medical Center

Ehrin J. Armstrong

University of Colorado Denver

Khung Keong Yeo

National Heart Centre Singapore

Reginald I. Low

University of California Davis Medical Center

Steven F. Bolling

University of Michigan–Ann Arbor

Dali Fan

University of California Davis Medical Center

W. Douglas Boyd

East Carolina University

Reginald Low

University of California Davis Medical Center

Edris Aman

University of California, Davis

Cooperative Institutions

University of California, Davis

103

University of California Davis Medical Center

Valve (United States)

Columbia University Irving Medical Center

Cardiovascular Research Foundation

Cleveland Clinic

Washington University in St. Louis

University of California, San Francisco

Emory University

NewYork–Presbyterian Hospital

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Long‐term safety and durability of percutaneous septal sinus shortening (The PS³ System™) in an ovine model

Catheterization and Cardiovascular Interventions (2008)

Jason H. Rogers David A. Rahdert Gary R. Caputo Patricia Takeda Igor F. Palacios

Chronic implants of the PS(3) system were conducted in an ovine model to assess durability and safety at up to 1 year follow-up.The long-term durability and safety of emerging percutaneous devices for functional mitral regurgitation remain largely unknown.The PS(3) system (consisting of interatrial septal and great cardiac vein devices connected by an adjustable suture bridge) was placed in eight healthy adult sheep. The mitral annular septal-lateral dimension in systole (SLS) was acutely reduced by 15-20%. Animals were sacrificed at up to 12 months postimplant and characterized by intracardiac echocardiography, cardiac computed tomography (CT), and histopathology. In vivo forces exerted on the PS(3) bridge were measured by means of a novel load cell catheter.At 3, 6, and 12 months after implantation, intracardiac echocardiographic and CT showed the PS(3) systems to be intact without erosion and with overall sustained reductions in the SLS. Histopathologic assessment revealed each component correctly deployed in its respective target site without evidence of erosion, thrombus, or device fracture. The SLS was 26.5 +/- 1.7 mm preimplant, 22.0 +/- 1.4 mm post-PS(3) (17.0% reduction), and 22.0 +/- 2.1 mm at latest follow-up. Mean forces exerted on the bridge in vivo ranged from 1.16 N to 1.87 N.The PS(3) System demonstrated excellent biocompatibility without evidence of erosion, thrombosis, or perforation at up to one-year follow-up in this chronic healthy ovine model. Forces exerted in the PS(3) system were relatively modest and should contribute to the durability of the device.

Perforation

Thrombogenicity

10.1002/ccd.21818

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Citations (16)

Contemporary Review in Interventional Cardiology: Mitral Annuloplasty in Secondary Mitral Regurgitation

Structural Heart (2021)

Jonathan Yap Steven F. Bolling Jason H. Rogers

Secondary mitral regurgitation (SMR, also known as functional mitral regurgitation or FMR) is one of the most prevalent types of valvular heart disease and occurs when the left ventricle dilates, causing papillary muscle displacement, chordal leaflet tethering, and impaired leaflet coaptation despite an otherwise structurally "normal" mitral valve. Mitral annular dilation is a common feature of SMR, and is a significant contributor to impaired leaflet coaptation. Surgical mitral annuloplasty has been used commonly since first description in 1955 and can normalize mitral annular dimensions and restore leaflet coaptation in properly selected patients. Numerous reports utilizing surgical mitral annuloplasty have established the efficacy of annular reduction in reducing SMR, but have also identified anatomic subsets in which annuloplasty is less effective. With the advent of transcatheter annuloplasty procedures, it will be imperative that members of the heart team have a clear understanding of normal and diseased mitral valve anatomy, and the risks, benefits, and technical considerations of various mitral annuloplasty procedures. This review describes the procedure of mitral annuloplasty in treating SMR, starting with describing the relevant anatomy and physiological mechanisms, followed by reviewing the evidence behind current surgical and transcatheter techniques.

Mitral valve annuloplasty

Papillary muscle

Chordae tendineae

10.1080/24748706.2021.1895457

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Citations (7)

Complexities of vascular intervention for erectile dysfunction

EuroIntervention (2014)

Jason H. Rogers

10.4244/eijv10i1a5

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Citations (0)

Coronary plaque dimensions and composition by intravascular ultrasound radio frequency lesion segment analysis in stable and unstable angina patients

Coronary Artery Disease (2009)

Andreas König Øyvind Bleie Darius Dudek Steve Marso Jason H. Rogers

We hypothesized that the plaque composition and plaque type classification differs between acute coronary syndrome (ACS) and stable angina (SA) patients.We analyzed culprit lesion (CL) and nonculprit lesion (NCL) of ACS patients compared with target lesion (TL) and nontarget lesion (NTL) of SA patients by intravascular ultrasound radio frequency analysis in 874 lesion segments of 424 patients (ACS: 193 patients/SA: 231 patients). Comparing all lesion segments in ACS and SA patients did not show significant differences in absolute or relative plaque composition. However, necrotic core area was larger in CL versus TL (0.9+/-0.7 vs. 0.7+/-0.5 mm, P=0.005) and all plaque components were significantly higher in CL compared with NCL and TL compared with NTL, respectively. A higher amount of thin cap fibroatheroma lesions (15.2 vs. 5.1%, P<0.0001) was detected in ACS compared with SA patients. Fibrocalcific lesions were lower in ACS patients (3 vs. 10.5%, P<0.0001).The differentiation in CL/NCL of ACS and TL/NTL of SA patients revealed significant differences in plaque composition and plaque types when examined by intravascular ultrasound radiofrequency analysis. However, considerable overlap between plaque characteristics exists for ACS and SA patients.

Intravascular Ultrasound

Culprit

Target lesion

Vulnerable plaque

Unstable angina

Stable angina

10.1097/mca.0b013e32832ac5d3

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Citations (3)

Occluder Therapy for Residual Mitral Regurgitation After Transcatheter Repair

Elsevier eBooks (2018)

Gagan D. Singh Thomas W. Smith Jason H. Rogers

10.1016/b978-0-323-54695-9.00016-0

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Citations (0)

Percutaneous Management of Mitral Regurgitation

Springer eBooks (2013)

Jason H. Rogers John M. Lasala

10.1007/978-1-4471-4528-8_28

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Revascularization for Arteries in the Pelvis

Interventional Cardiology (2016)

Femi Philip Jason H. Rogers

Erectile dysfunction (ED) is a common medical problem affecting over 50% of men between the ages of 45-75 years. The current therapy for ED uses pharmacologic agents such as phosphodiesterase-5 inhibitors (PDE5i) that increase penile arterial blood flow and improve endothelial function. This chapter reviews the normal penile arterial blood supply, describes the angiographic anatomy in ED, and discusses the available literature on microsurgical and endovascular techniques to treat vasculogenic ED. The most frequent anatomic variation occurs when the internal pudendal artery (IPA) ends as the artery of the urethral bulb or less frequently the perineal artery. Patients at risk for atherosclerosis or with established coronary artery disease or peripheral vascular disease can be screened for the presence of vascular ED using a five-question subset of the International Index for Erectile Function (IIEF) questionnaire. Patients who have ED without psychogenic or organic cause should be referred for Doppler ultrasound examinations in collaboration with a urologist.

10.1002/9781118983652.ch76

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Endovascular Treatment of Erectile Dysfunction

Springer eBooks (2013)

Jonathan Paul Jason H. Rogers Atman P. Shah Sandeep Nathan

10.1007/978-1-4614-7312-1_102

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Citations (1)

ANTERO-POSTERIOR MITRAL ANNULAR DIAMETERS AND CLINICAL OUTCOMES IN THE COAPT TRIAL

Journal of the American College of Cardiology (2024)

Jason H. Rogers Thomas W. Smith Jeroen J. Bax Federico M. Asch Scott Lim