Md Abdur Razzak

Shaheed Suhrawardy Medical College

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Shin Sik Choi

Myongji University

AKMA Sobhan

Shaheed Suhrawardy Medical College

Quazi Audry Arafat Rahman

Centre for Research and Development

Muhammad Nazrul Islam

Nishtar Medical College and Hospital

Inhwan Hwang

Pohang University of Science and Technology

Dong Wook Lee

Chonnam National University

Donghwa Chung

Seoul National University

Md Hasanul Haque

University of Nevada, Reno

Seong‐Jun Cho

Kangwon National University

Mohosana Khanam

Shaheed Suhrawardy Medical College

Cooperative Institutions

Bangabandhu Sheikh Mujib Medical University

Shaheed Suhrawardy Medical College

Dhaka Medical College and Hospital

Seoul National University

Bangladesh Agricultural University

Kyung Hee University

Myongji University

University of Dhaka

Dhaka University of Engineering & Technology

National Institute of Cancer Research and Hospital

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Fabrication of zein and κ-carrageenan colloidal particles for encapsulation of quercetin: In-vitro digestibility and bio-potential activities

Journal of Industrial and Engineering Chemistry (2022)

Vikash Chandra Roy Md Abdur Razzak Truc Cong Ho Duraiarasan Surendhiran Jin‐Seok Park

Zeta potential

10.1016/j.jiec.2022.04.007

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Citations (24)

Silicon Valley to Silk Road: Chimerica to Chiorld

Asian Journal of International Affairs (2021)

Md Abdur Razzak

No Abstract available.

Silicon valley

10.3126/ajia.v1i1.44764

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Citations (0)

Evolution of rubisco complex small subunit transit peptides from algae to plants

Scientific Reports (2017)

Md Abdur Razzak Dong Wook Lee Yun-Joo Yoo Inhwan Hwang

Chloroplasts evolved from a free-living cyanobacterium acquired by the ancestor of all photosynthetic eukaryotes, including algae and plants, through a single endosymbiotic event. During endosymbiotic conversion, the majority of genes in the endosymbiont were transferred to the host nucleus and many of the proteins encoded by these genes must therefore be transported into the chloroplast after translation in the cytosol. Chloroplast-targeted proteins contain a targeting signal, named the transit peptide (TP), at the N-terminus. However, the evolution of TPs is not well understood. In this study, TPs from RbcS (rubisco small subunit) were compared between lower and higher eukaryotes. Chlamydomonas reinhardtii RbcS (CrRbcS) TP was non-functional in Arabidopsis. However, inclusion of a critical sequence motif, FP-RK, from Arabidopsis thaliana RbcS (AtRbcS) TP allowed CrRbcS TP to deliver proteins into plant chloroplasts. The position of the FP-RK motif in CrRbcS TP was critical for function. The QMMVW sequence motif in CrRbcS TP was crucial for its transport activity in plants. CrRbcS TPs containing additional plant motifs remained functional in C. reinhardtii. These results suggest that TPs evolved by acquiring additional sequence motifs to support protein targeting to chloroplasts during evolution of land plants from algae.

Chlamydomonas reinhardtii

Chlamydomonas

Transit Peptide

Green algae

10.1038/s41598-017-09473-x

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Citations (22)

A case of Young Stroke due to Moyamoya Disease

Journal of Armed Forces Medical College Bangladesh (2020)

Md Abdur Razzak Ghulam Kawnayn Fateha Naznin Quazi Audry Arafat Rahman

Moyamoya disease is a disease in which certain arteries in the brain are constricted. Blood flow is blocked by the constriction, and also by blood clots (thrombosis). A collateral circulation develops around the blocked vessels to compensate for the blockage, but the collateral vessels are small, weak, and prone to bleeding, aneurysm and thrombosis which may result in TIA, recurrent ischemic or hemorrhagic stroke or seizure. The disease may manifest in pediatric age or young adults. In May 2019 we have diagnosed a young lady with Moyamoya disease who presented with right sided hemiplegia, motor aphasia and dysphagia. She was labeled as hypertensive 6 months prior to this event and used to take anti-hypertensive irregularly and gave past history of occasional headache. Her CT scan and MRI of brain revealed left sided ischemic infarct involving frontotemporoparietal region and cerebral angiogram revealed narrowing of left MCA and non-visualization of distal part. There is extensive fine collaterals (Moyamoya vessels) giving the appearance of puffed smoke. The right ACA and MCA were also narrowed with appearance of early collateral vessels. She was treated with aspirin, PPI, NG feeding, antihypertensive medication, physiotherapy, rehabilitation therapy and other supportive care. His condition gradually improved and discharged on 2.7.19. He was referred to Department of Neurosurgery for cerebral revascularization by STA-MCA (superficial temporal and middle cerebral arteries) bypass surgery after stabilization and MR perfusion study. Journal of Armed Forces Medical College Bangladesh Vol.15 (1) 2019: 110-113

Moyamoya Disease

Stroke

Collateral circulation

Perforating arteries

10.3329/jafmc.v15i1.48659

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Relationship between Thickness of Early Oral Tongue Carcinoma (T1, T2) with Cervical Lymph Node Metastasis

Bangladesh Journal of Otorhinolaryngology (2021)

Md Abdur Razzak Belayat Hossain Siddique Azharul Islam Md Hasanul Haque Md. Abdus Sattar

Background: Carcinoma of oral tongue is the most common oral cancer and because of its structure and function is prone for early local and regional spread of cancer. The final outcome of a primary tongue carcinoma patient depends upon various prognostic factors like thickness of tumor, depth of invasion, size of lesion and neck node 67metastasis. Risk of metastasis and spread to neck nodes increases with increase in tumor thickness Methods: This prospective observational study was carried out in the Department of Otolayngology- Head & Neck Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka for 18 months. Thirty patients with early oral tongue carcinoma i.e.T1 & T2 as per UICC and AJC criteria were included in this study by purposive non-randomized sampling technique. Result of the study were expressed as mean, standard deviation (+SD), frequency and percentages. Unpaired Student’s t-test and Pearson’s correlation co-efficient (r) test were performed. Results: Result of the study showed the mean (+SD) thickness of the tumor was 3.62 (+1.46) mm. Minimum thickness 1.1mm and maximum thickness 7.8mm. Only 21 (70%) subjects neck node were metastasized from tongue and mean (+SD) tumor thickness of the positive neck node metastasis was 5.54 (+1.07) mm and negative neck node metastasis was 2.87 (+0.75) mm. This indicated a significant difference between the groups. Pearson’s correlation co-efficient r (+0.981) which indicated tumor thickness was positively correlated with neck node metastasis. Conclusion: Tumor thickness of the early oral carcinoma positively correlated with neck node metastasis. Correlation between thickness and metastatic lymph node can help planning the treatment regimen and indicate the disease prognosis. Bangladesh J Otorhinolaryngol; April 2021; 27(1): 25-35

Primary tumor

10.3329/bjo.v27i1.53202

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Hypothyroidism with too Many Associations Case Report

Journal of Armed Forces Medical College Bangladesh (2022)

Md Abdur Razzak Fahd Bin Zia

Hypothyroidism is one of the common endocrine disorders. Amongst other causes, autoimmune hypothyroidism is clinically more important. It has got many adverse effects on metabolism, cardiovascular, musculoskeletal, fetomaternal and mental health. It's associated with obesity, dyslipidemia, IHD, inflammatory myopathy, depression etc. It is responsible for menorrhagia, subfertility, recurrent abortion, prematurity, fetomaternal morbidity and mortality. It may be associated with other organ specific or multisystem autoimmune diseases like SLE, vitiligo, alopecia, type-I DM, pernicious anemia and others. We have diagnosed a case of autoimmune hypothyroidism who had all the classic features of hypothyroidism. He had low FT4 and very high TSH. Autoimmunity was confirmed by high titer of anti TG and anti TPO antibody. In addition he had dimorphic anaemia, alopecia, diastolic hypertension, dyslipidemia, IHD, Vit D deficiency, myopathy, peripheral neuropathy, depression and dementia. His condition has been improved with Thyroxin replacement, lipid lowring drugs, anti anginal drugs, iron, calcium, folic acid, Vit-D supplementations, exercise, physiotherapy and other symptomatic and supportive measures. He was advised for consultation with dermatologist and periodic follow up. JAFMC Bangladesh. Vol 17, No 1 (June) 2021: 42-45

Dyslipidemia

Depression

Autoimmune thyroiditis

10.3329/jafmc.v17i1.56722

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Digital health interventions for cervical cancer care: A systematic review and future research opportunities

PLoS ONE (2023)

Md Abdur Razzak Muhammad Nazrul Islam Md Shadman Aadeeb Tasfia Tasnim

Cervical cancer is a malignancy among women worldwide, which is responsible for innumerable deaths every year. The primary objective of this review study is to offer a comprehensive and synthesized overview of the existing literature concerning digital interventions in cervical cancer care. As such, we aim to uncover prevalent research gaps and highlight prospective avenues for future investigations.This study adopted a Systematic Literature Review (SLR) methodology where a total of 26 articles were reviewed from an initial set of 1110 articles following an inclusion-exclusion criterion.The review highlights a deficiency in existing studies that address awareness dissemination, screening facilitation, and treatment provision for cervical cancer. The review also reveals future research opportunities like explore innovative approaches using emerging technologies to enhance awareness campaigns and treatment accessibility, consider diverse study contexts, develop sophisticated machine learning models for screening, incorporate additional features in machine learning research, investigate the impact of treatments across different stages of cervical cancer, and create more user-friendly applications for cervical cancer care.The findings of this study can contribute to mitigating the adverse effects of cervical cancer and improving patient outcomes. It also highlights the untapped potential of Artificial Intelligence and Machine Learning, which could significantly impact our society.

10.1371/journal.pone.0296015

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Citations (6)

HOG feature descriptor based PCA with SVM for efficient & accurate classification of objects in image

Md. Golam Sarowar Md Abdur Razzak Md Abdullah Al Fuad

In Computer vision, object recognition is a very important component and also very challenging. Intention of This paper is to exploit a high confidence object detection framework that boosts up the classification performance with less computational burden and cost efficient. Features are extracted from images by using Histograms of Oriented Gradients (HOG) technique and then for generating principle components as well as reducing dimensions Principal Component Analysis (PCA) has been applied on the extracted features. For classification of objects Support Vector Machine (SVM), Random Forest, Input mapped classifier, M5P classifier and Gaussian process classifier have been employed. A comparative study on performance of those approaches have been conducted. Moreover, for better clarification of the dataset, statistical and automated analysis have been considered. Overall findings demonstrates that, Principle Component Analysis (PCA)based Support Vector Machine (PSO) outperforms other approaches by depicting accuracy of 94.02% and highest F-Score measurement.

Contextual image classification

10.1109/iacc48062.2019.8971585

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Citations (2)

Delineating the interaction mechanism of glabridin and ovalbumin by spectroscopic and molecular docking techniques

Food Chemistry (2021)

Md Abdur Razzak Shin Sik Choi

Docking (animal)

Hydrophobic effect

Isoflavonoid

10.1016/j.foodchem.2020.128981

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